DEPARTMENT OF THE INTERIOR

BUREAU OF GOVERNMENT LABORATORIES

BIOLOGICAL LABORATORY

SOME QUESTIONS RELATING TO VIRULENCE
OF MICRO-ORGANISMS, WITH PARTICULAR
REFERENCE TO THEIR IMMU-
NIZING POWERS

BY

RICHARD P. STRONG, M. D.

MANILA
BUREAU OF PUBLIC PRINTING
1904

Prardined

49292.

PREVIOUS PUBLICATIONS OF THE BUREAU OF GOVERNMENT LABORATORIES.

No. 1, 1902, Biological Laboratory.-Preliminary Report of the Appearance in the Philippine
Islands of a Disease Clinically Resembling Glanders. By R. P. Strong, M. D.
No. 2, 1902, Chemical Laboratory.-The Preparation of Benzoyl-Acetyl Peroxide and Its Use
as an Intestinal Antiseptic in Cholera and Dysentery. Preliminary Notes. By Paul
C. Freer, M. D., Ph. D.

No. 3, 1903, Biological Laboratory.-A Preliminary Report on Trypanosomiasis of Horses in
the Philippine Islands. By W. E. Musgrave, M. D., Acting Director Biological
Laboratory, and Norman E. Williamson, Assistant Bacteriologist Bureau of Government
Laboratories.

No. 4, 1903, Serum Laboratory.-Preliminary Report on the Study of Rinderpest of Cattle and
Carabaos in the Philippine Islands. By James W. Jobling, M. D., Director of the
Serum Laboratory.

No. 5. 1903, Biological Laboratory.-Trypanosoma and Trypanosomiasis, with Special Refer-
ence to Surra in the Philippine Islands. By W. E. Musgrave, M. D., Acting Director
Biological Laboratory, and Moses T. Clegg, Assistant Bacteriologist Biological Labora-
tory.

No. 6, 1905.-I. New or Noteworthy Philippine Plants. II. The American Element in the
Philippine Flora. By Elmer D. Merrill, Botanist. (Issued January 20, 1904.)

No. 7, 1903, Chemical Laboratory.-The Gutta Percha and Rubber of the Philippine Islands.
By Penoyer L. Sherman, jr., Ph. D., Chemist, Chemical Laboratory.

No. 8, 1903.-A Dictionary of the Plant Names of the Philippine Islands. By Elmer D.
Merrill, Botanist.

No. 9, 1903, Biological Laboratory.-A Report on Hemorrhagic Septicemia in Animals in the
Philippine Islands. By Paul G. Woolley, M. D., and J. W. Jobling, M. D.

No. 10, 1903, Biological Laboratory.-Two cases of a Peculiar Form of Hand Infection (Due
to an Organism Resembling the Koch-Weeks Bacillus). By John R. McDill, M. D., and
Wm. B. Wherry, M. D.

No. 11, 1903, Biological Laboratory.-Entomological Division, Bulletin No. 1, Preliminary
Bulletin on Insects of the Cacao. (Prepared Especially for the Benefit of Farmers.)
By Charles S. Banks, Entomologist Bureau of Government Laboratories.

No. 12, 1903, Biological Laboratory.-Report on Some Pulmonary Lesions Produced by ·
the Bacillus of Hemorrhagic Septicemia of Carabaos. By Paul G. Woolley, M. D.
No. 13, 1904, Biological Laboratory.-A Fatal Infection by a Hitherto Undescribed Chromo-
genic Bacterium: Bacillus aureus fœtidus. By Maximilian Herzog, M. D.

No. 14, 1904, Serum Laboratory.-Texas Fever in the Philippine Islands and the Far East.
By J. W. Jobling, M. D., and Paul G. Woolley, M. D.

No. 15, 1904, Biological and Serum Laboratories.-Report on Bacillus Violaceus Manilæ: A
Pathogenic Micro-Organism. By Paul G. Woolley, M. D.

No. 16, 1904, Biological Laboratory.-Protective Inoculation Against Asiatic Cholera: An
Experimental Study. By Richard P. Strong, M. D.

No. 17, 1904.-New or Noteworthy Philippine Plants. By Elmer D. Merrill, Botanist.
No. 18, 1904, Biological Laboratory.-I. Amebas: Their Cultivation and Etiologic Signifi-
cance. By W. E. Musgrave, M. D., and Moses T. Clegg. II. The Treatment of Uncom-
plicated Intestinal Amebiasis (Amebic Dysentery) in the Tropics. By W. E. Musgrave,
M. D.

No. 19, 1904, Biological Laboratory.-Some Observations on the Biology of the Cholera
Spirillum. By Wm. B. Wherry, M. D.

(Continued on third page of cover.)

No. 21.-OCTOBER, 1904

DEPARTMENT OF THE INTERIOR

BUREAU OF GOVERNMENT LABORATORIES

BIOLOGICAL LABORATORY

SOME QUESTIONS RELATING TO VIRULENCE
OF MICRO-ORGANISMS, WITH PARTICULAR
REFERENCE TO THEIR IMMU-
NIZING POWERS

BY

RICHARD P. STRONG, M. D.

MANILA
BUREAU OF PUBLIC PRINTING
1904