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DILUTE PHOSPHORIC ACID.

The attention of the profession is respectfully invited to some points of difference between Horsford's Acid Phosphate and the dilute phos. phoric acid of the pharmacopoeia. Horsford's Acid Phosphate Is A SOLUTION OF THE PHOSPHATES OF LIME, MAGNESIA, POTASH, AND IRON IN SUCH FORM AS TO BE READILY ASSIMILATED BY THE SYSTEM, and It is containing no pyro or meta-phosphate of any base whatever. not made by compounding phosphoric acid, lime, potash, etc., in the laboratory, but is obtained in the form in which it exists in the animal system. Dilute Phosphoric Acid is simply phosphoric acid and water without any base. Experience has shown that while in certain cases dilute phosphoric acid interfered with digestion, Horsford's Acid Phosphate not only caused no trouble with the digestive organs, but promoted in a marked degree their healthful action. Practice has shown in a great variety of cases that it is A PHOSPHATE WITH AN EXCESS OF PHOSPHORIC ACID that will better meet the requirements of the system than either phosphoric acid or a simple phosphate. Phosphorus," as such, is not found in the human body, but phosphoric acid in combination with lime, iron, and other bases, i. e., the phosphates, is found in the bones, blood, brain, and muscle. It is the phosphates, and not the simple phosphoric acid, that is found in the urine after severe mental and physical exertions or during wasting diseases.

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We have received a very large number of letters from physicians of the highest standing, in all parts of the country, relating their experience with the Acid Phosphate, and speaking of it in high terms of commendation.

Physicians who have not used Horsford's Acid Phosphate, and who wish to test it, will be furnished a sample on application, without expense, except express charges.

RUMFORD CHEMICAL WORKS,

PROVIDENCE, R. I.

BEWARE OF IMITATIONS.

OF

CALISAYA BARK AND IRON.

Each dessertspoonful contains

Free Phosphorous, gr. 1-100.

Total Calisaya Alkaloids, gr. §.

Pyrophosphate of Iron, gr. i.

This is the only preparation containing in solution Free Phosphorous, Pyrophosphate of Iron, and Calisaya Alkaloids.

It is the only Elixir of Calisaya which contains an effective proportion of Alkaloids.

The proportion of these Alkaloids is invariable-of Quinia, Quinidia, Cinchonia, Cinchonidia, and Chiniodine. The exhibition of a given dose of these Alkaloids in solution with agreeable pungent aromatics, produces more emphatic and certain results than the same dose in the pill or powder form.

It is the only preparation extant containing Phosphorous in solution. A dessertspoonful actually forms a very effective dose of the combined remedies

for an adult.

It is a beautiful bright amber-colored elixir, acceptable alike to the taste and to the stomach.

As a tonic in convalescence from fevers and debilitating diseases; as a brain and nerve tonic and invigorant, these remedies have long enjoyed high repute. As combined in this "Phosphorized Elixir" (Fairchild), better results may be anticipated than from any other form in which they are prepared.

It is important to specify Fairchild's, owing to the great number of similarly named but valueless "Elixirs of Calisaya."

FAIRCHILD BROS. & FOSTER,

82 and 84 Fulton St., New York.

Reviews and Book Notices.

A TREATISE ON THE PRINCIPLES AND PRACTICE OF MEDICINE. De. signed for the Use of Practitioners and Students of Medicine. By AUSTIN FLINT, M.D., LL.D., late Professor of the Principles and Practice of Medicine and of Clinical Medicine in the Bellevue Hospital Medical College, New York. Sixth edition, revised and largely re-written by the author, assisted by William H. Welch, M.D., Professor of Pathology in Johns Hopkins University, Baltimore; and Austin Flint, M.D., LL.D., Professor of Physiology in the Bellevue Hospital Medical College, New York. Philadelphia:

Lea Brothers & Co. 1886.

The preface from the pen of the son of the author thus refers to the changes this edition embodies:

"The claim in the preface to the fifth edition that the eliminations, substitutions, and additions rendered it essentially a new work,' can with equal propriety be made for the present edition as compared with the edition issued in 1881. Among the entirely new articles, special attention may be called to the following: Infectious Tumors, Syphilitic Diseases of the Lungs, Cerebral Syphilis, General Considerations relating to Inflammatory and Structural Diseases of the Spinal Cord, Spastic Cerebral Paralysis of Children, Hereditary Ataxia, Myxedema, Multiple Neuritis, General Pathology of Fever, and Milk Sickness. In addition to these new features, many articles have been entirely rewritten; and in nearly every article changes and additions, some of them very important, have been made.

"As already stated, the sixth edition contains a full consideration of recent discoveries concerning the bacterial origin of various infectious diseases, as will be rendered evident by a consultation of the article on Vegetable Parasites in the chapter on Etiology, and articles in the chapter treating of Tuberculosis, Typhoid Fever, Cholera, etc."

We decline either to commend or to criticise, in a popular sense, any portion of this most complete work. The first would be to borrow high, confirmatory views; the last to run our own ways, and give liking to nothing but what is framed by ourselves and hammered on our anvil.

We fully concur in the statement that its influence on Englishspeaking physicians of the present generation is unsurpassed; and we think it would be hard to suggest a material improvement upon its present technical or literary aspect. It is worthy of consideration as a near attainment to a most exalted and glorious ambition.

HOW WE TREAT WOUNDS TO-DAY: A Treatise on the Subject of An- •
tiseptic Surgery which can be Understood by Beginners. By R.
T. MORRIS, M.D., late House Surgeon to Bellevue Hospital, New
Second edition. New York and London: G. P. Putnam's

York.

Sons.

1886.

It is painful to see such a high stage of the art presentative as this little book exhibits, employed to perpetuate such poverty of taste and such luxury of self-sufficiency.

It is true that from it may be learned one way of using corrosive sublimate solutions, iodoform, and animal ligatures and sutures, as well as articles which wide courtesy could hardly claim as antiseptic; and its practical character makes it have a present adaptation to general practitioners and to students. An attendant, but not an unimportant result, will be effected in an adverse influence upon superlatively bad styles of didactic writing and sophistical reasoning, of which it stands a prominent example.

To transform now our author into some such a traditional character as the Richard Roe of court fictions, and to consider his cause apart from his method of presenting it, if it be neither a pleasant nor an easy task, seems none the less a duty.

The immortality Sir Joseph Lister has won has its dependence upon the fact that sepsis makes unresisted advance only in unhealthy tissue. To use the words of this great man, "Healthy living tissues have the power of preventing the development of bacteria in their vicinity." The causal relation of the ubiquitous

bacterium is not yet made out; and this is all the more wonderful when we think how often the wish has fathered the thought.

With these important concessions in mind, rational wound treatment may be promoted, and Listerism may sooner be reduced to its proper sphere and accorded its merited triumph. OUTLINES OF THE PATHOLOGY AND TREATMENT OF SYPHILIS AND ALLIED VENEREAL DISEASES. By HERMANN VON ZEISSL, M.D., late Professor at the Imperial-Royal University of Vienna. Second edition. Revised by Maximilian Von Zeissl, M.D., PrivatDocent for Diseases of Skin and Syphilis at Imperial-Royal University of Vienna. Translated by H. Raphael, M.D., Attending Physician for Diseases of Genito Urinary Organs and Syphilis, Bellevue Hospital, Out-patient Department. 8vo., pp. 402. York: D. Appleton & Co. 1886.

New

It is a little curious to note the difference of the scope of this book from that of the preceding.

This is the outcome of a life devoted to a single subject. It is a good, practical work, full of German plainness, and painstaking. It is restricted to expounding the doctrines of its subject already proposed. It claims to contain very little that is

new.

A partial and a hurried examination of it has won a very favorable impression of its value from us.

THE SURGERY OF THE PANCREAS, AS BASED UPON EXPERIMENTS AND CLINICAL RESEARCHES. By N. SENN, M. D., of Milwaukee, Wis., Attending Surgeon to the Milwaukee Hospital; Professor of the Principles and Practice of Surgery and of Clinical Surgery in the College of Physicians and Surgeons, Chicago, Ill.

The above reprint of a paper read before the American Surgical Association, April 29, 1886, has appeared upon our table. We regard its appearance as most timely, as the surgery of the pancreas has heretofore been almost a terra incognita in the profession. The operations heretofore considered admissible have been for the cure of cysts and the formation of an external pancreatic fistula. Our author has based his conclusions upon quite a number of apparently careful and painstaking vivisections, and

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