ing at once, and continued to thrive as long as the food lasted. In the meantime I had ordered the food from both St. Paul and Milwankee, but could not obtain it in either city.

When the food I had left them was gone, and as no more of it was to be obtained, they were placed upon the use of another food, which is in very popular use for infants, but it failed to meet the requirements, and, though the greatest of care was used in its preparation, it was but two or three days before they commenced showing signs of inanition; but this time the one designated as No. 2 failed first, dying about a week after we had suspended the use of Carnrick's soluble food. The other died four days later.

In the case of these two infants the changes for better and for worse were so decidedly marked that there could be no question as to the effect of the foods, and the parents, as well as myself, are convinced that could we have had the soluble food to continue with both children would be alive to-day

About a month ago, C. S., case No. 1, commenced showing all of the evidences of a return of the old condition of inanition, though what caused it I could not learn. Not having yet obtained a supply of Carnrick's food, I prescribed the food that was substituted for it in the case of the other infants, but the child still failed.

In the meantime I had written a brother of mine in Chicago, who succeeded in obtaining some of Carnrick's food of Fuller & Fuller.

As soon as it arrived the child was fed with it, and the patient is now (two weeks later) nearly restored to its former plump, healthy condition.

If my fellow-practitioners will try this preparation, I can assure them that they will not only be pleased with it, but will save the life of many a little patient that would otherwise be sacrificed.-Theadore L. Hatch, M. D., in Northwestern Lancet.

THERAPEUTIC NOTES (J. J. Berry, m. d., in N. E. MED. MO.) The following items which are taken from my note book have been of such use to me that I am led to think they may furnish useful hints to others as well. Few of them are original, but have been derived from all possible sources and have been utilized by me to a greater or less extent.

Tonics should be administered with certain alteratives when given for long periods of time; for instance, quinine with mercury; cod-liver oil with iodide of potash; and iron with various salines.

Emetics are not given enough. Effects upon the liver and intestinal tract are often more obtainable in this way than by any other.

The diarrhea of phthisis is usually relieved by a pill of g. terebinth, cupri sulph. and opium.

The best treatment of engorgement of bronchial mucous membrane is to keep the bowels open.

The best respiratory stimulants are ammonia, atropia, strychnine, ipecac and squill.

Expectorant.-Eth. sulph., gutts. v-x every three or four hours. Pruritus (general).-Potass. brom., grs x, potass. liq. gutts. x, three or four times daily.

Lumbago.-Potass. cit., grs xx ter die with hypodermics of morphine

and atropia.

Salines act better after physiological doses of calomel.

The action of quinina is increased by half drachm doses of bitart. of potash.

Belladonna or bromide of potash often prevents the disagreeable effects of iodide of potash.

Alcohol helps the organism to tolerate large doses of quinine.

The addition of alcohol to croton oil renders the latter less powerful but none the less effective.

Chorea.—F. E. cimicifuga in gradually increased doses.

Columbo checks colliquative diarrhea and relieves irritability.

Senega for the bronchitis and emphysema old people. Balsams act best in chronic diseases of the bronchial mucous membrane.

The secretion of urea is increased by sod. salicyl., sod. benzoat, colchichum and hydrarg. bichlorid, as well as by the salts of potash.

Salines have an increased cathartic effect if given in a concentrated form, withholding all liquids.

Iodine is one of the best anti-suppurative remedies. It has been used with success in typhoid fever and pneumonia.

Calomel, one half grain, is said to relieve dryness of tongue in six

hours.

Tonsillitis.-Local applications of bicarbonate of soda.

The cough of phthisis is often relieved by remedies which act upon the liver.

Counter irritation of the neck, over course of pneumogastric nerves, will often relieve asthma.

Arsenic is one of the best tonics in chlorosis and the anemia of

women.

A saturated solution of sod. bicarb. best relieves pain of cautery burns.

Acids best relieve phthisical dyspepsia.

Chloroform increases the secretions.

Chloral hydrate or chloroform water in painful affections of the stomach.

Grain doses of ipecac act as an hepatic stimulant.

The pains of spinal irritation are often relieved by arsenic.

Vaseline is much used for conjunctivitis.

Caffeine slows the action of the heart, increases the amount of urea and decreases the amount of albumen excreted.

Salicin will often relieve dysmenorrhea. sillitis and muscular pain.

It is of great value in ton

Epilepsy.-A hypodermic of morphine will often abort a paroxysm. Sick-headache.-A hot foot bath with a fifteen grain dose of chloral. Hoarseness.—Tr. guaiac am. ten drops on sugar every half hour. Salicylate of soda.

Weak heart.-Tr. stramonium and tr. digitalis, of each ten drops, three times daily.

Lead paralysis.-Large doses of strychnia.

Diarrhea (in teething children).—Infus. camomile.—Columbo.
Regurgitation (of infants).-Calomel gr. j; aq Oj; teaspoonful every

15 min.

Eructation, Pyrosis and Fermentation.-Ac. carbol, gr. i-ii in mint

water.

Inhalations of steam impregnated with oil of peppermint is almost a specific in relieving painful affections of the throat.

Calomel is one of the very best remedies in many of the acute diseases of children; the latter are so very tolerant of the drug that it is almost impossible to salivate with laxative doses. Its antipyretic effects and its sedative action upon the intestinal tract is fully appreciated only by those who have used it.

The value of carbonate of ammonia in the respiratory diseases of children is not fully recognized. It should be given in large doses well diluted in milk.

Ovarian pain is best relieved by belladonna, arsenic, velerianate of zinc and carbonate of iron.

Muriate of ammonia relieves congestion of the pelvic viscera. Permanganate of potash in two grain doses is an excellent emmenagogue for strumous subjects.

TREATMENT OF ANGINA PECTORIS. -Huchard by his novel treatment, based upon his undoubtedly correct pathological views, records a greater number of cures of true angina than any other clinician has ever obtained previously (twenty cures). His treatment consists principally in the exhibition of iodides, which, as is well known, are alone able to cure the affections of the arterial system, even those of a non-s - syphilitic nature. The iodide of potassium, or better, of sodium, given without intermission for months, and even years, in a daily dose of 1 to 2 grammes (15 to 30 grs.), will with certainty at first diminish the frequency and intensity of the anginal paroxysms, and finally bring about their definite and complete disappearance.

The curative effects of the iodides of sodium and potassium in aneurism of the aorta and various other arterial affections show the powerful influence of the iodine treatment on pathological conditions of the vascular apparatus.

In aortitis, both of the acute and chronic type, we find most frequently dilatation of the aorta and elevation of the subclavian artery. Under the influence of the iodine treatment both symptoms can be relieved promptly and permanently.

The most refractory cases in regard to this treatment are those in which the aortitis and the arterio-sclerosis approach their termination, for the iodides, however powerful they are, cannot suppress an arterial atheroma. In general, it can be said with propriety that "the iodides are the digitalis of the arteries." Huchard's routine formula is :—

Sig. Two to four teaspoonfuls daily, to be taken in a cup of tea.Therap. Gazette.

SYMPTOMS AND PATHOLOGY OF POISONING BY PTOMAINES, or CaDAVERIC ALKALOIDS.-The attack occurs in the majority of cases in from eighteen to twenty-four hours after the introduction of the poison into the system. The symptoms, as collected from a large number of cases, are pain and a sense of weight in the stomach, vomiting and diarrhea, extreme prostration, dry condition of the mucous membranes of the mouth

and throat, irregular pyrexia, dysphagia, vertigo, aphonia and noises in the head. Double vision, ptosis, dilated pupils, scarlatiniform rash, muscular twitchings and tetanic spasms are of frequent occurrence. Rudolph Boehm says it is, after the acute symptoms have subsided, essentially a kind of typhus, continuing a tedious course for weeks, with symptoms that indicate morbid blood processes and changes in nerve centers not unlike those in diabetes mellitus. Weak pulse and cold skin characterize the latter stages of the poisoning. In the rapidly fatal cases, death results from paralysis of the respiratory muscles. Pneumonia, nephritis or some other complication may supervene. Patients often make very slow Death usually occurs on the fifth or sixth day after poisoning. In the acute stage death occurs in the majority of cases in from twelve to twenty-four hours. In forty-eight fatal cases reported by Boehm, six died on the first day, two on the second, four on the fourth, three on the fifth, two on the sixth, eight on the seventh, five on the eighth, three on the ninth, eight on the tenth, two on the thirteenth, one on the fourteenth, one in three weeks, and three died at still later dates.

recoveries.

The pathological conditions in man, so far as observed, are quite identical with those produced by the action of ptomaines on lower animals. The mucous membranes of the esophagus, mouth and stomach are either hyperemic or dry and parchment like. The liver, spleen and brain are more or less hyperemic; ecchymoses are sometimes found in the stomach. The kidneys are congested with some effusion of blood into the tubuli. The lungs are often congested, edematous and pneumonitic, with the tubes partially filled with a bronchial exudate.—J. U. Barnhill, M. D., in Cleveland Med. Gazette.

CHLORAL HYDRATE LOCALLY. The local application of chloral hydrate is very serviceable in many diseases, both on account of the relief of pain afforded and the cleansing of the parts. For cancerous ulceration of glands and of the uterus, phagadenic ulcerations, eczema, impetigo, ulcerated legs, herpes zoster, pleurodynia and neuralgia, local employment of chloral, half an ounce in a pint of water, with a little glycerine, has been productive of much benefit. Ulcerated surfaces become healthy by comparison, discharges less offensive and pain is reduced to a mimiThese results are probably due to direct action on the peripheral nerve terminations.-Med. World.

mum.