One of the most important acts of the U. S. Pharmacopeial Convention of 1900, which recently met in Washington, was the passage of resolutions or general principles, one of which was upon the subject of "Doses," instructing the committee on revision and pubi cation of 1900 that: "After each pharmacopeial article (drug, chemical or preparation), which is used or is likely to be used internally or hypodermically, the committee is instructed to state the average approximate (but neither a minimum nor a maximum), dose for adults and, where deemed advisable, also for children. It is to be distinctly understood that neither this convention nor the committee on revision created by it intends to have these doses regarded as obligatory on the physicians, or as forbidding them to exceed them whenever in their judgment this seems advisable. The committee is directed to make distinct declaration to this effect in some prominent place in the new pharmacopeia." It was further direct ed that doses should be expressed metrically followed by the older apothecaries weights and measures. This action is most important for the reason that it will place in the hands of the medical and pharmaceutical professions some authoritative information upon average approximate doses. As the case now stands, every therapeutist is, practically, a law unto himself regarding the dose of this or that product-no two of them agreeing in every instance-and it will be a source of satisfaction to know, approximately, just what dosage is proper. In line with this action, the enterprising firm of H. K. Mulford Co., of Philadelphia, has been the first, in the newly issued edition of its catalogue, to give under the list of fluid extracts, etc., the dose of the products in the older form of weights and measures, followed by the newer metric system. Such a list will be of great service to pharmacists and physicians. The catalogue, which is an unusually comprehensive one, embraces 234 pages of closely printed subject matter, and is unique in the fact that it contains a therapeutic index, this firm having been the first to add a therapeutic index in its price list. The therapeutic index classifies remedial agents according to the diseased conditions in which they are indicated and will be highly valuable and suggestive to physicians, as it embraces the latest teachings of therapeutics. The catalogue refers to tablets and triturates, lozenges, hypodermic tablets, fluid extracts, elixirs, syrups, wines, tinctures, spirits, liniments, ointments, effervescent salts, and a complete list of similar products, together with many special preparations, and last but not least, as the fame of the Mulford biological products has spread to all corners of the world, there is also given some very interesting information regarding diphtheria antitoxin, vaccine virus, and various other preparations of similar character. The book contains many other good things, pharmaceutical and medical, and we would suggest that our readers send to the H. K. Mulford Co. for a copy of their price list, which we learn will be sent upon request. FOR SALE-Home and good paying practice. Apply or write Lock Box No. 14, Blackburn, Mo. THE MEDICAL HERALD will be sent to new subscribers from now till January 1, 1902, for one dollar. Send in your name today. THE CROWN Surgical Chair possesses all the desirable features of the older chairs and a number of new ones,which will pay every one to investigate, especially those who want the best on the market. See card in this issue. PHYSICIANS' SUPPLIES-Attention is called to the advertisement of Mr. J. E. Long, in this issue, and those in need of supplies of any kind are advised to write Mr. Long for prices before buying elsewhere, as he is in a position to quote the lowest prices and best terms on standard goods. DOCTOR DO YOU WRITE?-We have on hand a limited number of finest $3.00 grade, gold fountain pens, which we will furnish to subscribers only at $1.00 each. If you are not a subscriber, remit $2.00 (in stamps or money order) and you will receive the Herald for a year and pen and filler by next mail. WORTHY OF ATTENTION.-We call the attention of our readers to the advertisement of the Robinson-Pettet Co., Louisville, Ky., which will be found on another page of this issue. This house was established fifty years ago, and enjoys a widespread reputation as manufacturers of high character. We do not hesitate to endorse their preparations as being all they claim for them. ACUTE ARTICULAR RHEUMATISM.-It is self-evident that in diseases where fever is present there is an insatiable thirst and taste for something sour, and when the sourness is combined in a product of Antipyretic and Antirheumatic qualities it is doubly beneficial. Very refreshing and at the same time efficacious are a few grains of Citrophen sprinkled on a small lump of cracked ice and inserted in the mouth of a feverish patient.-Dr. W. H. Vail. Med. Summary. The well known firm of Reed & Carnrick has again placed in physicians' hands a brochure, superior to any heretofore issued, on the different states and conditions of the blood in health and disease, embellished with many very fine colored illustrations. The great interest taken in blood examinations at the present time, the crystalization of our knowledge into concrete facts, and their adoption to clinical medicine makes this brocure an extremenly welcome one to many physicians, who do not care for the larger text-books on this subject. The plates, illustrating the condition of the reds and the whites in chlorosis, pernicious anemia, leukemia and the parasitic blood diseases are well executed and true to science. The reproduction of the triple stain is well rendered and the plates might well adorn some first class work on hematology. Those physicians who have not received a copy of this brochure may obtain one by addressing the publishers. MEDICAL HERALD COMPANY, PUBLISHING HOUSE, ST. JOSEPH, MISSOURI. CORNER SIXTH AND CHARLES STS. Editorial Telephone 327. Telephone Nos. 196 and 890 Subscription, $1.00 a year in advance. Single Copies, 10 cents. THE HERALD'S circulation being among a class of physicians who PAY THEIR SUBSCRIPTIONS (and consequently READ each issue), this journal naturally offers the best opportunity to those advertisers who desire to reach the thrifty and progressive practitioners of the "Middle West." Rates made known on application BLOOD TREATMENT OF DUO DENITIS. By T. J. Biggs, M. D., Stanford, Conn. John O'Connors, aged 32, Irish, admitted Jan. 1, 1900. Diagnosis: Duodenitis. The patient complained of having been suffering for some four weeks, and during that time had been under the care of one of my colleagues, who had exhausted all treatments he knew of to accomplish a relief for the patient, but without effect. He. therefore, brought the patient to me. He was suffering from a nausea and vomiting: stools were frequent, containing little faecal matter, greenishyellow in color, mixed with undigested food. He had no appetite, and suffered greatly from distress in the stomach when he did eat, and was so weak that he could hardly stand. He had a temperature of 103, and suffered considerably from paroxysmal colickly pains, situated above the umbilicus. There was also considerable localized tenderness above the duodenum. The patient was put in bed and the rectum as high up as the sigmoid flexure was washed out with cold Thiersch solution, followed by a bovinine-pure injection. He was put on a half teaspoonful of bovinine in lime water every half hour and one-eighth of a grain of codea every three hours. On January 7th the bovinine was given, a teaspoonful every hour, in lime water, alternating with peptonized milk. January 15th the patient's fever had subsided, the stools were less frequent and contained some faecal matter; vomiting and nausea had disappeared; paroxysms of colic were greatly reduced in severity, the patient was stronger, and the abdomen less tender. The bovinine was now increased to a wine-glassful every three hours. From this time on the patient made an uninterrupted recovery, and was discharged cured, January 27th, feeling as he expressed it, “splendid". THE NEW TREATMENT OF SYPHILIS WITH BIN-IODIZED OIL.-(By Dr. Chapelle, Paris.)The specific bin-iodized oil," _recommended by Panas, Dieulafoy, Lancereaux, Brissaud, Fournier and the leading specialists of the diseases of the skin, is a very dilute and unsatisfactory preparation, but a great improvement in the administration of mercury, has been recently made, by utilizing the solubility of nascent mercuric iodide in a strictly neutral aseptic oil, which keeps indefinitely. This "specific bin-iodized oil" which contains one per cent of BgI2, has been aptly called Cypridol, (a name which gives no clew to the patient to those around him as to the nature of the medicament), can be used either hypodermically or taken in capsules. or Cypridol is vastly superior to the usual soluble or insoluble mercurials, the assimilation and subsequent elimination of which is uncertain, while salivation, vomiting and diarrhea are amongst the least of their disadvantages. Since Ricord's time, insoluble mercurial treatment has been largely adopted on account of the severity of the soluble salts, but their assimilation is slow, irregular and gives rise to considérable trouble in the alimentary canal, even when given in combination with small doses of opium. All disadvantages of this nature, which are inevitable with soluble and insoluble mercural preparations, are avoided with cypridol, which does not affect the stomach or digestive organs and rarely produces salivation even in massive doses. It is conveniently exhibited in capsules of 20 centigrammes each of which represents exactly 1-32nd of a grain of mercuric iodide. One capsule should be taken with the two principal meals daily, and this dose may be increased to five capsules daily, but should not be exceeded, except under special conditions dependent on the susceptibility of the patient to the treatment. Our experience in the clinics, shows that it is advisable to commence the treatment of the capsules or injections of cypridol (or to alternate their administration) as soon as syphilis is recognized and to continue it for three consecutive years, even if there is an apparent cure after a short time. During the first three months, the treatment may be suspended eight days every month, during which interval small doses of iodide of potassium, sodium or strontium are given. For the following three months, the cypridol treatment should be administered every alternate fortnight, and after that, eight days of each succeeding month. This radical treatment with cypridol, will insure the patient's permanent cure; it is indispensable, however, to maintain the best hygienic conditions of life. Frequent, but not too prolonged hot baths; washing, to free the skin from irritation are useful, and care should be taken to keep the buccal cavity exceptionally clean by careful washing and gargling of the throat with boracic acid and chlorate of potassium. An ointment of the same should be used to anoint the genital and anal orifices. The great antiseptic and antizymotic value of cypridol can be utilized in a great number of cases. It constitutes an excellent specific for bacteriological affections or parasites of the alimentary canal, the skin and the scalp and is indicated in the treatment of serious affections, fistulas, cold abscesses, white tumors (in hip, knee, ankle), lupus, spina ventosa and other manifestations of tuberculosis. Suc cessful experiments have been made in the Paris hospitals on neoplasms anthrax. furunculosis. paludal intoxication and in the great majority of epidemic discases. USEFUL CHART-We are just in receipt of an excellent drawing from Messrs. Battle & Co., of St. Louis, illustrating "fracture of femur below trochanters." The muscles involved are beautifully and accurately defined, and we would suggest that physicians write Messrs. Battle for a copy, which will be sent free of charge. In addressing the company, kindly refer to the Herald. ERGOAPIOL-(Smith)— Ergoapiol is the par-excellence of combinations for the treatment of amenorrhoea, dysmenorrhoea and suppressed menstruation. It is a well tried, successful and most meritorious preparation. Its eificacy has been proved and verified by nearly every prominent physician of New York City and many others throughout the entire world. In therapeutic properties it is reliable and positive. Its efficacy is not only derived from this special combination, but particularly from the apiol used in its preparation, and which is a special active preparation that fully and entirely represents apium in the most active form. This apiol, the process and production of which is our exclusive property and discovered by us, is not to be confounded with the inert complex concentration found in the market under this name. NIRVANIN FOR COCAIN HABIT. -M. Axford, M. D., Buffalo, writes of his experience with Nirvanin as follows: "M. A. B., aged 20 years, good personal and family history, acquired the habit of using cocain locally applied to nostrils for the relief of 'hay fever.' When he came under my care he was using enough to keep him awake nights and to totally incapacitate him for work of any kind during the day. To furnish relief sought for by cocain I had him use as a substitute nirvanin in 4 per cent solution. On removal of a polypus, and use of the solution of nirvanin when needed for relief, he has been enabled to stop the use of cocain altogether, and is now using neither chemical. I fully believe that nirvanin tided him over the habit. From its use he reports no toxic effects whatever." UNIFORM PURITY. The revi sion of the United States Pharmacopoeia has called close attention to the adulterations and chemical inferiority of sulphate of quinia, and has emphasized the question of substitutes and succedanea. The worthlessness of so many so-called "substitutes" has prejudiced the profession against them as a whole, and the inadequacy of the average sucedaneum has decidedly vexed medical men. The question may as well be set aside, however, now that we have it more than answered by Pil. Quin. Dad, which is now available as a strictly pure two-grain pill-in which th equinine salt is redeemed rather than reformed. The quinine in these pills has the merit of uniform purity and strength, and the absence of the characteristic faults of the sulphate. It is quinine with uniform food value, with liberal antiseptic qualities, and unwasted in the stomach or intestines. The materia medica has a hearty wel come for these pills because of their purity, acceptability and utility. should be sufficient, I think, for me to say that in all my work I am employing Pil. Quin. Dad exclusively, as my experience has taught me to prefer it over the uncertain commercial products.-W. H. Morse, M. D., F. S. S., Westfield, N. J. It A very interesting discussion about the origin of gout took place at the International Medical Congress, in Paris, in which the most prominent authorities of Germany, France and England (Goettingen), the disease is caused by an intrusion of uric acid in the tissues. Epstein makes a distinction between two forms of gout. In the first, the disease only effects a few parts of the body, and the individual may attain high age. In the second, more seldom found, the uric acid reached right from the beginning all parts of the body, and is most likely caused by a serious disease of the kidneys. Prof. Le Gendre (Paris) after comparing the different theories about the origin of gout, expressed the opinion that the disease is caused by faulty metabolism. Prof. Duckworth (London) calls the gout a disturbed nutrition causing an imperfect metabolism in certain organs, most likely in the liver and also perhaps in the kidneys. The true indications of gout mnaifest themselves mainly in those joints and tissues which, in consequence of mal-nutrition, or of injuries, lost their force of resistance. The salt crystals deposited in the tissues can be dissolved and eliminated, but are liable to remain permanent in badly nourished parts of the body, causing the most vehement pains. While the authorities come to the conclusion, that the ultimate cause of the origin of uric acid has not as yet been sufficiently explored, they unanimously agreed that of all the uric acid eliminators, Kutnow's Improved Effervescent Powder, composed of the most valuable and curative elements of the most celebrated European Mineral Springs Waters, occupies the first place and is unequalled. AN INFALLIBLE GALACTOPOIETIC.-I have often wondered if physicians as a rule were fully aware of the inestimable value of Maltine with coca wine as a galactopoietic. I have proved over and over again that for this is a remedy par excellence mothers with babies at the breast. I have given this preparation a large and widespread- test and have never been disappointed. In several cases where mothers stated that they had been unable to nurse their babies at previous confinements, the use of Maltine with coca wine by the mothers at meal-time and bed-time resulted in an abundant supply of good rich milk and enabled them to nurse their babies as long as was necessary. The babies, as well as the mothers, were well-nourished, strong and robust. In fact, my patients and myself have been amazed at the prompt and permanent action of Maltine with coca wine, and words fail me when I attempt to express the satisfaction which I have derived from its use. I have also used Maltine with pepsin and pancreatin with most happy and gratifying results. Its benefits have been most pronounced in debilitated and rachite children where there was malnutrition and improper assimilation of food. Maltine with cascar sagrada is of great value as a regulator without debilitating. H. L. NEWELL, M. D. IN ANEMIA.-Cherokee, Ia., April 15, 1900-Waterbury Chemical Co., Des Moines, Iowa. Gentlemen:— I have given all the Cod Liver Oil preprations on the market an extended trial, but find after using Waterbury's Metabolized Cod Liver Oil with Creosote Carb. and Guaiacol for several months it acts much better in anemic cases with low vitality. Also find for reducing temperature in phthisis and as a nutrient tonic and builder it is superior to any preparation I have ever used. Very sincerely, Edw. Hornibrook, M. D. DE PUY'S ADJUSTABLE FIBER SPLINTS.-These splints are made of a fiber that has been saturated in a compound rendering them firm and non-pliable at ordinary temperature. Should the surgeon desire to change the shape in adjusting one of the splints, it can be done by holding it over a hot stove for a few minutes or by immersing in hot water, when it |