following report of three cases which I have successfully treated during the last few months with hydrozone and glycozone, which I consider not only harmless but the most powerful healing agents that I have ever used in my practice of thirty-five years. CASE I.-A man called on me on June 20th with gonorrhoea of four weeks duration, with profuse discharge, micturition painful and acute burning sensation along the entire urethral tract. Pus sacs had formed in the canal, the meatus was inflamed, and the gonococcus was active, as determined by microscopical examination. I prescribed injections of one part of hydrozone and ten parts of sterilized lukewarm water, an ounce for each injection, four times daily. After two days I reduced the proportion to one part of hydrozone and fifteen parts of lukewarm water, and I directed glycozone mixed with an equal amount of glycerine pure to be injected on his going to bed. The diet was not restricted, but no stimulents were permitted. In two days no gonococcus could be detected. The discharge was lessened, the pain and difficulty in micturition had ceased, and in twelve days the patient was well. Continence was imposed for two weeks. Doses of bromide of potassium and bicarbonate of sodium were administered from time to time in order to make the urine alkaline and quiet the patient. CASE II.-A married man contracted blennorhoea from a woman who had the whites. The same treatment was ordered, and with such satisfaction that the woman was also brought for examination and treatment. Result, a cure in each case within three weeks. CASE III.-A man 50 years oll, contracted gonorrhoea from a woman of the town. As the patient lived in the country, twenty miles out, no treatment was given until ten days after infection. Aggravated symptoms of gonorrhoea were present, and there was chordee every night; the patient, to use his own expression, was "plum wild." The hydrozone injections were ordered, one part to twenty, owing to the great sensitiveness of the urethra and the possibility of orchitis if a stronger injection was used, as there was a slight swelling of the testicles. The glycozone, diluted with equal parts of pure glycerin, was ordered at night. I also gave glycozone internally in medicinal doses, to allay a gastric disturbance due to nervousness. In this case the treatment was contined for twenty-five days. I sent my patient to his cattle ranch happy, WARREN E. DAY, M. D. A PLEASANT LETTER. Dr. F. M. Johnson, of No. 117 Beacon St., Boston, pays the following deserved compliment to The Maltine Company: "For more than fourteen years I have coustantly made use of a number of your preparations, and it gives me much pleasure to state that the results have been uniformly and eminently satisfactory. "By your courtesy, it has been my pleasure to inspect your plant, and to familiarize myself with the very interesting processes in operation, and I was particularly impressed with the extreme care, cleanliness and nicety that rules and pervades the entire atmosphere of your extensive establishment. "Maltine with Cod Liver Oil", I have prescribed very frequently. My patients take it readily, and it is easily assimilated. "Maltine with Cascara Sagrada" has proved in my hands to be the ideal tonic laxative. It has never disappointed me, and I have given it in hundreds of cases. "Malto-Yerbine" is of great value as an adjunct in the treatment of all bronchial difficulties,' HYPEREMESIS GRAVADARIUM. It is a satisfaction to the medical profession to know that Smith, Kline & French Co., Philadelphia, have at last placed in their hands a very effective means of overcoming this very stubborn and often serious symptom of the period of gesta We refer to the reported experience of Dr. A. J. Sauer, of Baltimore, who says: "Eskay's Food has proven serviceable to me in two cases of vomiting of pregnancy, being the only retained article where both food and medicine. were ejected.” A CONFOUNDING OF NAMES. There seems to have been a misunderstanding with regard to the appearance of the word "Gude" on many sign boards throughout the country. The word "Gude" refers to the maker of the signs, and not to Gude's Pepto Mangan, this statement in justice to the very ethical house of Messrs M. J. Brietenbach & Co., the sellers of Pepto Mangan in this country, who only advertise Pepto Mangan to the medical profession. IN CYSTITIS. J. L. Ridley, M. D., Huntsville, Ala., says: I have used S. H. Kennedy's Extract of Pinus Canadensis, both White and I can frequently cure gonorrhoea without any other remedy. I use either as an injection, and prescribe the Dark internally, where there is irritability about the mouth of the bladder. I have learned to regard it as a specific. In chronic cystitis I have derived great benefit from it, and in leucorrhea it relieves when many other remedies fail. It is a valuable remedy, and I have had marked success with it. AN INTERESTING RESUME. Abstract from an article entitled:-"Note on diastatic preparations," in the March, 1898. number of the Albany Medical Annals, by Dr. Willis G. Tucker, Professor of Chemistry, Albany Medical College. "Having recently completed a series of tests of some of the medicinal preparations of Malt and Cod Liver Oil, which is now so largely prescribed as digestive aids in certain forms of faulty digestion, with consequent imperfect food assimilation, no less than for their direct value as nutrients, it has seemed to me that the results obtained were of sufficient interest to warrant their publication with a brief statement of the method employed in determining the diastatic value of the articles examined. The samples were purchased by myself at drug stores in New York City, Troy and Albany early in January of the present year. The inquiry was restricted to a careful determination of the diastatic activity of the preparations since this is likely to vary, and upon this activity the remedial value of such articles largely depends. The methods employed in making this determination was one which I had previously employed in similar work, and which has been found to yield very satisfactory and concordant comparative results. Precisely the same method was employed in each determination, and the conditions were in all respects identical in all the tests. The results may be most readily understood if stated in parts by weight of maltose, or its equivalent, in reducing sugars, produced by one part of each of the preparations examined, and these were found to be as follows in the three tests which were made of each article: No. 1=4.42, 4.98, 4.24, the average being 4.54 It is, I think, fair to state that the first of these preparations was Maltzyme with Cod Liver Oil, and that these results plainly indicate its diastatic activity. A NEW ANESTHETIC. F. C. Wallis, M. D., F. R. C. S., in an article, entitled: Eucaine as a local Anesthetic when used Hypodermically, published in St. Bartholomew's Hospital Journal, August 1897, states having used Eucaine for some months past in St. Mark' and Charing Cross Hospital in nine removals of tumors, 44 rectal operations and two abdominal operations. The results of his experience with Eucaine are most satisfactory. He has used a solution of 4 pc. and he has never seen any signs of toxic effects, even when a considerable amount has been used. This percentage he found quite strong enough to produce absolute anasthesia for any small operation. He has in a large ischiorectal abscess, injected as much as 3 to 4 drachms subcutaneously without any ill eflects at all. The average amount required for a small operation was from 1 to 1 drachms of the 4 per cent. solution. One of the great boons this drug possesses is that the operator need not be at all nervous about using sufficient, and if the desired anesthetic effect is not produced by one drachm, the second or third can be used with every confi dence as to the safety of it. He frequently used it in the out-patient room for abscesses, and found it most useful, both in hospital and private work, for removing the redundant skin which is sometimes left after operations for hæmorroids. He has no after effects to record, and concludes that Eucaine has a great deal to recommend it. In the British Medical Journal of November 28th, 1897, Drs. W. Jobson Horne and Maclead Yearsley described their experience with Eucaine, which they have employed in 100 cases of diseases of the ear, nose and throat. They found that the pulse was not materially affected in either rate or character and they have not met with a case in which the drug per se influenced the cardiac action, It has been stated that Eucaine induces hyperæmia and on this account the drug is inferior to Cocaine, which produces an ischemia, so serviceable in investigating diseases of the nose. Upon the application of a 5 or 10 per cent. solution of Eucaine to the mucous membrane, hyperæmia will occur as an immediate result, this is in the majority of cases, but an initial blush rapidly passes off, and gives place to an ischemia, which as seen in the nose, is generally less marked than that produced by cocaine. Upon a further application there is no recurrence of hyperæmia, and the ischemia may be increased. In no case have we met with excessive or unexpected hæmorrhage following operations done under Encaine anesthesia, such is not uncommonly met with after the use of cocaine. This is no doubt accounted for by the action of Eucaine upon the peripheral vessels already alluded to. As regards the disturbances of sensation following the anesthetic action of the drug, more particularly in the case of the pharynx, these are not only less unpleasant and less marked than those produced by cocaine, but more transient, and, speaking generally, after the lapse of an hour from the time of application, the subjective sensations may be described as normal. Those who have experienced the effects of both drugs have expressed a decided preference for Eucaine. SANMETTO AN INVALUABLE ADDITION TO OUR MATERIA MEDICA. It gives me pleasure to state that Sanmetto at my hands has proven all that its manufacturers claim for it. I consider it an invaluable addition to our materia medica. Schuyler C. Graves, M. D., Grand Rapids, Mich. |