Uterus, malignant disease of, among colored women. Uterus. galvano caustic operations on. By Prof. Speigelberg. . 177 180 190 326 519 By SAMUEL 543 Uterus, malignant disease of, in various races. By Prof. J. J. CHI 544 SOLM. Uterus, introduction of sutures into the, after cæsarian section. By Vaccination, on success in. By FRANK P. FOSTER, M. D. " two cases of, relieved by operation. By Wood Smith, M. D. MAN, M. D. REVIEWS AND NOTICES OF BOOKS. Obstetric Operations, including the treatment of hemorrhage. By Archiv Für Gynaecologie. Von Profs. CREDÉ and SPEIGELBERG, Berlin.. 372 A Treatise on the Theory and Practice of Obstetrics. By Prof. WM. 376 A Practical Treatise on the diseases of children. By J. FORSYTH 554 Austrian Yearbook of Pædiatrics. Edited by Prof. RITTER VON RIT 555 Diseases and Injuries of the Eye. By GEORGE LAWSON, F. R. C. S. 558 558 559 749 Physical Exploration of the Rectum. By WM. BODENHAMER, M. D. On the Wasting Diseases of Infants and Children. By EUSTACE 750 750 751 Medical and Surgical Reports of the Boston City Hospital. 752 THE USE OF QUININE IN THE DISEASES OF CHILDHOOD. BY C. BINZ, M.D. Professor of Pharmacology in the University of Bonn, Germany. I HAVE once before published an article on the same subject,* and as my treating of it again may cause surprise, it will perhaps be well to state that since the publication of that first article nearly two years have elapsed, during which time much that was doubtful and uncertain has been cleared up and confirmed. There is no longer any doubt that quinia possesses superior antiseptic and antizymotic properties. Amongst all substances which, in moderate doses, are harmless to the system, and are not rapidly eliminated from and decomposed in it, quinine, and, perhaps, carbolic acid, stand at the head of the list. For external use, quinine * Jahrbuch für Kinderheilkunde, I. p. 233. Leipzig, 1868. is surpassed by many others, as, for instance, by chloride of mercury, which is, however, a violent corroding poison; or by alcohol, only the smallest part of which circulates through the blood in an undecomposed state. One of the first contributions of recent times on the therapeutic powers of quinine in septic affections was written by Gieseler.* A boy three years of age suffered from noma in a high degree. The gangrenous parts were removed, the sore cleansed, and covered several times daily with dressings dipped in a solution of the sulphate of quinine. The bad odor disappeared, and the formation of healthy granulations began as early as the second day, when the child sat up, was comfortable, amused himself, and partook of some fluid nutriment. The process of cicatrization went on rapidly to completion, and produced excellent healthy structure in a remarkably short time. Unfortunately, the strength of the solution employed is not stated. Gieseler also tried the local use of quinine with very good results in caries and necrosis, both of which are of very frequent occurrence in scrofulous children; but in addition to the local treatment he regards the condition of the system, and the improvement of the general health, to be of the greatest importance. Before quinine is exhibited in any of the internal diseases of infancy, with a view of obtaining its antiseptic or antizymotic effect, the question must be solved, whether the diseases are to be regarded as truly septic * Die Anwendung des Chinins in der Chirurgie: v. Langenbeck's Archiv, vol. iv. p. 550. The Use of Quinine in Surgery. |