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Department of Pharmacy.

WM. J. JACKSON, PH.G., M. D., Editor in Chief.

Professor of Pharmacy, College of Physicians and Surgeons, of San Francisco.

J. HENRY FLINT, Ph.G.

A. O. BOTHE, A. M., M. D.

A. F. WERNER, A. B., M. D.

T. W. CONNELLY, Ph.G.

COLLABORATORS.

J. J. KEEFE, Ph.G., M. D.
HAROLD COTTELL, Ph.G.
P. A. DUBOIS, Ph.G.

J. F. DILLON, A. M., M. D.

The Editor of this Department is not responsible for the views of contributors. All communications relating to the Editorial Department of Pharmacy should be addressed to DR. W. J. JACKSON, 44 Third Street, San Francisco, Calif.

TUBERCULOSIS.

An analysis of Moeller's work on "The Spread of Tubercle Bacilli," is given in the Progrés Médical. Flugge expressed the opinion that the dried sputum carried in the air and inhaled by healthy individuals was not a means of spreading contagion as common or as dangerous as mucus direct from the bronchi and very small particles of saliva containing the living bacilli; the phthisic when coughing, throwing out with each effort a large number of living organisms into his immediate surroundings. By a number of experiments on guinea-pigs, Moeller seems to have confirmed Flugge's theory; he placed the animals directly in front of coughing tubercular patients, the ultimate result being their tuberculization. Finally, the author shows that the bacillus is found in the nasal mucus of perfectly healthy individuals. P. A. D.

ANTISEPTIC INTERNAL MEDICATION.

Dr. Sluyts, in the Bulletin of the Anvers Medical Society, of January, gives the result of experiments made to determine the extent of the antiseptic properties communicated to urine by internal administration of certain supposed antiseptics. The bacterias used were aerobic and (as established by Morelle) are most frequently met with in cystitis: strepto- and staphylococci.

Dr. Sluyts endeavored to cultivate these microbes in urines voided by persons having taken oil of turpentine, Venice turpentine, copaiba, chlorate of potassium, boric acid, salicylate of soda, oil of sandalwood and salol. Of all these, only the last two were found to be really efficacious; the antiseptic action of

the others being almost nil. Sandal oil acts specifically on cocci and has but little action on bacilli, while salol destroys the two organisms and produces absclutely sterile urine.

The author took several daily 8-gramme doses of salol without experiencing any inconvenience; he, however, points out that he has had equally good results with 4 and 6-gramme doses. (This would prove the combination of oil of sandal and salol frequently prescribed by some of our genito-urinary specialists a good one, the further advantage being that any pharmacist can encapsulate it extemporaneously in the ordinary hard gelatin capsules.)-Translations from the French. P. A. DUBOIS, Ph. G.

HYGIENIC PROPHYLAXIS.

A suggestion which applies to our city of San Francisco has been made by Dr. L. Baret, of Paris, concerning open-air eatable shows, such as grocers, fruit dealers, butchers, etc., which usually encroach upon the sidewalks. He asserts that it has repeatedly been demonstrated that the number of bacteria, bacilli and particles of dirt of various nature accumulating on e wares are very numerous and constitute a danger to public health; the danger of course not being so great with articles boiled before consumption as with delicate fruits, such as raspberries, strawberies, cherries, etc.; these are apt to be brought to the table reeking with microbes, not to speak of likely contamination by handling and picking over. Dr. Baret would enact laws compelling all those dealers to keep their wares in the stores and covered. Some such ordinance would benefit us, but, like the expectoration law, it would be difficult of introduction and enforcement. P. A. D.

NEW PREPARATIONS.

Among the newer preparations published in the Annales de Policlinique of Lille are the following:

Syrup of benzoate of mercury.

R. Benzoate of mercury.
Iodide of potassium..

Syrup of anise...

5 decig.

50 grammes
q. s. for 1 litre

The benzoate of mercury and the iodide of potassium are

dissolved in a small quantity of water and the syrup added.

A tablespoonful (20 c.c.) contains 1 centig. of benzoate of me cury and 1 gramme of iodide of potassium.

Dose: 20 to 40 c.c. a day. Indications: syphilis.

Pills of phosphate of guaicol.

B. Guaicol phosphate.

Extract gentian..

.10 grammes

q.8.

Indications:

To be divided into 100 pills. Dose, 2 to 6 with meals. Each pill contains 1 decig. of guaicol phosphate. Tuberculosis, bronchitis, pulmonary antisepsis.

Unguentum domesticum (Monats. f. p. Dermat., 1899).

This is Unna's formula for a non-irritant, quick-drying appli

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Styrax, oil of cade, ichthyol, starch, sulphur, camphor, lime water, lead water, bichloride of mercury, acetate of lead may be incorporated with the above, according to indications; it is, however, incompatible with carbolic, salicylic and pyrogallic acids, with the oxides of zinc and mercury, with subnitrate of bismuth Unguentum domesticum is of great service in acne, eczema, etc. P. A. D.

HYPODERMIC SOLUTION OF SUPRARENAL CAPSULES. Langlois' Formula:

R. Suprarenal capsules...

Boiled water....

Chloride of sodium

80 centig.

10 grammes

Sulphate of sodium, ......each 7 centig.

Triturate the capsules with the solution of the salts, macerate 24 hours and filter. 2 to 5 c. c. are injected daily, or every other day. Indications: Addison's disease.

Arsonval's Formula:

B. Suprarenal capsules
Glycerine...

....each 10 grammes

The capsules are finely divided and macerated 24 hours, then the paste is triturated with: Boiled water containing 2.5:100 sodium chloride 5 c.c. This is allowed to stand half an hour filtered through sterilized paper, by pressure with carbonic oxide. 5 to 8 c. c. diluted with an equal quantity of water are injected.

P. A. D.

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of an egg, and added to a tumblerful of cold water.

4. R. Tartar emetic

Ext. licorice...

5 centig.

q. 8.

For 20 pills. Dɔse: 3 to 4 a day. Tartar emetic reduces the temperature and clears the lungs.

-From the formulary of the Union Medicale du Canada.

NEW STAINS FOR GONOCOCCUS.

Pick's stain for gonococcus consists of Ziehl's carbol-fuchsine, 15 drops; concentrated alcoholic solution of methyl blue, 8 drops; distilled water, 20 cc. Strain cold for ten seconds, wash, dry and mount. The gonococcus is stained deep blue, other bacteria light blue, cell nuclei lighter blue, protoplasm pink. Lanz's stain consists of saturated solution of fuchsine in 2 per cent aqueous phenol, 10 cc.; saturated solution of thicnin in 2 per cent aqueous phenol, 30 cc. to thirty seconds, and wash with water. by thionin, and nuclei take both colors. be freshly prepared.

Mix, stain for fifteen Gonococci are stained Both solutions should

LISTERINE INCOMPATIBLE WITH FERRIC SALTS.

Listerine and other preparations of similar composition owe their incompatibility with tincture of chloride of iron to the presence of benzoic acid, which is a constituent of listerine and nearly all of the imitations of that article. In contact with ferric salts in solution benzoic acid throws down a flesh color precipitate. If it is desired to add tincture of ferric chloride to one of these eucalypto!-thymol preparations, the benzoic acid and oil of wintergreen usually added to these solutions should be omitted.

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66

Why I Use Pepto-Mangan “Gude”; an Experimental

Demonstration.

By WM. KRAUSS, Ph. G., M. D., Memphis.

Director of the Microscopic Laboratories, Memphis Medical College; Pathologist and Visiting Physician to St. Joseph's Hospital, etc., etc.

(Read before the Memphis Medical Society.)

Some five years ago I wrote a paper for the Memphis Medical Monthly, giving a résumé of the evolution of the iron compounds, and appended a report of cases giving blood counts, etc. The manufacturers of the preparation I preferred saw fit to reproduce the case reports in the ir pamphlets, but said nothing about the reasons that induced me to prefer their product.

At a recent joint meeting of physicians and pharmacists I was criticized for opposing the use of ready-made compounds, while still advocating the use of Pepto-Mangan "Gude," which is a proprietary preparation. I hesitated considerably about bring

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