In all cases where the continued use of cod SCOTT & BOWNE, Chemists, 409 Pearl St., New York. TRI-IODIDES (HENRY'S) Colchicin 1-20 grain. 7 Liquor Sali-lodides. A powerful alterative and resolvent. glandular and hepatic stimulant, and succedaneum of the iodides. Indicated in all conditions dependent upon perverted tissue metabolism; in lymphatic engorgements and functional visceral disturbances, in lingering rheumatic pains which are "worse at night" Bone, periosteal and visceral symptoms of late syphilis; for the removal of all inflammatory, plastic and gouty deposits. A remedy in sciatica, megrim, neuralgias, lumbago and muscular pains; the gouty and rheumatic diathesis; acute and chronic rheumatism and gout; chronic eczema and psoriasis, and all dermic disorders in which there is underlying blood taint. An hepatic stimulant increasing the quantity and fluidity of the bile. Relieves hepatic and intestinal torpor; does not cause the unpleasant gastric symptoms of potassium iodide. THREE CHLORIDES (HENRY'S) Each drachm contains Proto-Chlor. Iron 1-3 gr.; Bi-Chlor. Mercury, 1-128 gr.; Chloride Arsenic, 1-280 gr.; CalisaCordial. Dose, 1 to 2 drachms. ya 12-oz. bottle $1.00 Liquor Ferrisenic. An oxygen-carrying ferruginous preparation, suitable for prolonged treatment of children, adults and the aged. Indicated in anemia and bodily weakness, convalescence from acute diseases and surgical operations; boys and girls at the age of puIn children with chorea, rickets, or who berty, and the climacteric period in women. are backward in development, or in whom there exists an aversion to meats and fats. Prolonged administration never causes iron headache." As an adjuvant for potassium iodide the undesirable manifestations known as iodism can be removed. Stimulant to the peptic and hydrochloric glandular system of the stomach, especially serviceable in the impaired appetite, nausea, vomiting and other gastric symptoms of alcoholic subjects. MAIZO-LITHIUM Liquor Lithium Maizenate. A genito-urinary sedative, and active diuretic; solvent and flush indicated for the relief and prevention of renal colic; a sedative in the acute stage of gonorrhea, cystitis and epididymitis; in dropsical effusions due to enfeebled heart or to renal diseases. As a solvent in the varied manifestations of gout, goutiness aand neurotic lithemia, periodical migrainous headache, epigastric oppression, cardiac palpitation, irregular, weak or intemittent pulse; irritability, moodiness, insomnia and other nervous symptoms of uric-acidemia. Decidedly better, more economical, extensive in action and definite in results than mineral waters. Those cases of irritable heart, irregular or intermittent pulse so frequently met with by insurance examiners and found to be due to excess of uric acid, are special indications for Maizo-Lithium. HENRY PHARMACAL CO., LOUISVILLE, KY. READ AT THE Original Papers SEMI-ANNUAL MEETING HELD IN KANSAS CITY, MARCH 23 AND 24, 1905. SURGICAL VERSUS X-RAY TREATMENT OF RODENT ULCERS AND EPITHELIOMATA OF THE FACE, WITH REPORT OF OPERATED CASES. C. O. Theinhaus, M. D., Milwaukee, Wis. N these days of general and universal therapeutic radioactivity in the field of malignant disease I thought it altogether timely to honor your kind invitation by bringing before you today as a subject for discussion a comparison of the surgical and X-ray treatment for cases of epitheliomata and so-called rodent ulcers of the face, which however in my opinion, considered from a pathologic anatomical standpoint, are nothing else but epitheliomata and do not originate from the endothelium, as some writers believe. I was prompted to write this paper by the observation of two cases within the last year, in both of which the use of the X-ray for about six months with intervals had no curative effect whatsoever; in fact both patients complained that they could observe considerable increase in size of the carcinoma during and after the treatment with the Roentgen ray. The cases in question give the following history: CASE I. Mr. D., 53 years of age from Stoughton, Wis., kindly transferred to me for operation by Dr. I., from Stoughton, complains that he was suffering for one year and a half from an ulcerative growth in the middle of his left cheek. Different caustics were applied for several months, and they were of no avail, the X-ray was used at interals for about six months without any effect whatsoever; in fact the patient believes that the ulcer was growing larger every month. When I saw him, the following status presented itself: In the middle of the left cheek a cauliflower growth of the size of a small apple, easily bleeding by touch, was discernable. The microscopical examination (Dr. Beffel) revealed an epithelioma. At the same time the region of the parotid gland was swollen to a large extent and at first appearance it seemed probable that this gland was involved in the malignant process. Since this probability would have necessitated the removal of the entire parotid gland, and with it the loss of the facialis nerve with its consequences of paralysis of the entire half of the face, I decided, before resorting to such a radical procedure, to first remove the entire growth and then to determine by microscopial examination the extent of the carcinoma in the region of the parotid gland and whether the swelling of the parotid Giant gland was produced by an inflammatory process or by malignant transformation. This examination performed by Dr. Beffel and myself revealed that in the line of excision near the parotid gland no malignant tissue was present. Quite a few giant cells as you can see on this microscopical drawing (plate No 1.) were found in the slides taken from this part. cells are found, as we know, wherever necrosed material is imbedded in the tissues and have nothing to do with a natural healing process of malignant neoplasms as one believed at one time. The entire wound was left open, packed with iodoform gauze and the X-ray applied to the wound daily for twenty sessions. On plate No. 2 is shown the wound four weeks after operation in a state of healthy granulation. Plate No. 3 shows the result as it is today (seven months since the operation). This case is interesting not only from the standpoint of X-ray treatment, which had no effect whatsoever on the epithelioma, but also from a microscopical standpoint, because by microscopical examination the boundaries of healthy and cancerous tissue were determined, and thereby a great part of the parotid gland together with the facialis nerve saved. CASE II. Mr. S., from Deerfield, Wis., was suffering for two and a half years from a rodent ulcer in the region of the left nasal bone extending to the inner canthus of the left eye. One year previous he saw a skin specialist in Chicago, who advised the use of the X-ray, and warned him decidedly against an operation. The use of the Roentgen ray, however, proved of no avail, the ulcer increasing instead of diminishing in size. I excised the ulcer, as shown in plate No. 8, and after applying the X-ray to the wound for twelve sessions, I covered the defect by a pedunculated flap taken from the forehead. Plate No. 4 shows the result eight weeks |