Transactions of the Section on Dermatology of the American Medical Association, Volume 67

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American Medical Association Press, 1916
 

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Page 254 - ... discharge must always and in all cases be present ; all that is implied is that exudation, either on the surface or into the deeper layers of the skin, is, has been, or will be a prominent feature in any given case. The definition of eczema here given excludes all forms of inflammation of the skin caused by chemical or mechanical irritants. The artificial dermatitis set up by such agents is identical anatomically with the eczematous process, and gives rise to lesions indistinguishable from those...
Page 122 - ... an aleukemic form, if the blood is normal, a subleukemic form if the number of the white blood cells is normal or very little increased, but the proportion of lymphocytes is augmented, and a leukemic form when there is an absolute, permanent, progressive increase of lymphocytes and the total number of leukocytes is augmented.
Page 254 - Inflammation of the skin of artificial origin is often similar in symptomatology to that of eczema and may, indeed, be considered identical." But many authorities are not willing to rest with this. They insist that it differs from an ordinary dermatitis of external origin by certain added factors, usually factors of personal equation in the patient. The position of Malcolm Morris 1 Fordyce, "The Modern Conception of Eczema,
Page 284 - The eruption not infrequently extends beyond the irritated areas, at times being observed on distant parts of the cutaneous surface and also generally in certain instances. The usual type of eruption noted is the vesicular or the erythematosquamous. The eruptions mentioned as occurring in the cases in this article have lasted for weeks, months and years, and showed a marked tendency to relapse. It is rather hard to explain the susceptibility of some persons to certain irritants, while others are...
Page 194 - After the oral-administration of salvarsan, arsenic is found in the bile and urine, at the end of twenty-four hours, but it disappears by the end of seventy-two hours. 3. Twenty-four hours after the oral administration of salvarsan to cats, the number of bacteria in the intestinal tract appears to be reduced, the reduction being most striking in the lower end of the ileum. 4. Salvarsan...
Page 284 - Microorganisms play only a secondary rdle in the causation of the disease. Practically every occupation and every irritant may produce an eczema. The portions of the skin exposed to the irritant determine the site of the outbreak. The eruption not infrequently extends beyond the irritated areas, at times being observed on distant parts of the cutaneous surface and also generally in certain instances. The usual type of eruption noted is the vesicular or the erythematosquamous. The eruptions...
Page 327 - List of Fellows of the American Medical Association who registered in this Section at one or more of the last five Annual Sessions, together with Fellows who have subscribed to the Transactions of the Section for 1918.
Page 208 - We do not advise the use of arsenobenzol (salvarsan) by mouth as a routine, inasmuch as there are much more efficient avenues of administration. Its use is to be reserved for patients who for some reason cannot take the drug by intravenous infusion or intramuscular injection.
Page 207 - CONCLUSIONS 1. Experiments on animals have demonstrated that arsenobenzol (salvarsan) can be administered by mouth in solution or in capsules and become absorbed into the blood. 2. The proof that absorption takes place is evidenced by the fact that a distinct destructive influence on trypanosomes in the blood of experimentally infected animals is exerted. 3. In a general way it may be stated that about one ninth or one tenth of the dose required in solution by mouth produces an equivalent effect...
Page 207 - Clinically, it has been found that the drug may be given in doses of 30 mg. (| grain) three times a day for many weeks without producing disturbing symptoms except mild digestive distress, and this only in a relatively small proportion of cases.

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