were given every ten minutes. The pulse immediately began to improve, and in a few hours could be counted readily. The râles remained for three days. The chill was undoubtedly malarial, as it was followed on the second day by the typical paroxysm.-RALPH I. LLOYD, M. D.

Asarum Europæum,30 in Dysmenorrhaa.-Julia W., age 27, married. Very nervous, fidgety woman. Menstruates regularly and profusely, but the first two days she suffers from intense headache, so severe that she cannot move. It often rises to the dorsal region, when it will almost take her breath away. Clinical Symptoms (Hering): At appearance of menses violent pain in small of back, which scarcely permits her to breathe. Remarks: Dose every evening. After next menses she reported: Free from pain, and felt better generally. She remained well.-DR. MARTIN DESCHERE.

Eucalyptus in Chronic Nasal Catarrh.-Palmyre H., age II years. Nose continually filled with profuse white and yellow discharge of mucus from anterior and posterior nares. Consequently she can only breathe through wide open mouth. Her teeth feel raw and sore; she has to bite something all the time. Child looks pale and is flat-chested. Feels tired and languid. Clinical Symptoms: Sore pain in upper incisors. Posterior nares inflamed and smarting. Thick, whitish discharge on hawking. (Hering) Chronic catarrh of nasal passages even when purulent and fetid (Allen). Cures chronic catarrh of nasal passages and acute coryzas. Remarks: Five drops in half a glass of water, dessertspoonful three times daily. From that time she gradually improved, and after a month had but an occasional watery discharge from nose, which had become entirely free so that her mouth breathing was a thing of the past. IBID.

Natrum Sulph. 30 in Panaritium.-Walpurga M., chambermain, age 21 years. Had a Panaritium on the first finger of her right hand about six months ago, which suppurated and caused much suffering at that time, making her unfit to do any work for ten days. Now the left index finger is affected in same way. Whole of second and third phalanges were swollen and deep red. Pain was severe, and she had passed a sleepless night with fever. There was no fluctuation, and I told her I would try and stop the trouble right there. Pathogenetic Sympttoms: Sticking, ulcerative pains under nail of right index finger and similar pains in the phalanges of various fingers. Pulsation in tip of little finger, etc. Clinical Symptoms (Allen): Panaritium, the pain is better out of doors. Remarks: In watery solution, a teaspoonful every two hours. After two days she came in smiling, the pain having ceased rapidly, and the swelling had commenced to decrease. After two more days the finger was well.-IBID.

30

Xanthoxylum fraxineum in Dysmenorrhea.-Elsa N., age 19. Menstrual pain before and after flow. The pains start in the hypogastrium and shoot down the thighs. Sick headache, with nausea and vomiting. The menses are profuse and always late, but pre

ceded and followed by a milky leucorrhoea. The blood is offensive. The patient is a very hysterical and hyperesthetic nature. Pathogenetic Symptoms: Menses profuse and too early. Cutting pains, sudden pains in right ovarian region, extending down thigh and passing over to left side. Leucorrhoea white, milky, after menses. Shooting from region of right ovary to hip, thigh and back, with gushing, milk-white leucorrhoea ceasing suddenly. During menses, which are too early and painful, cramp-like pain in head and abdomen; hungry, but food nauseated, when vomiting the stomach felt as if rising and falling. Clinical Symptoms: Neuralgic dysmenorrhoea, pains going down the anterior portion of the thigh, mostly left side. Neuralgic dysmenorrhoea, with neuralgic headaches. Remarks: A powder every night and morning, to begin two weeks before menstruation is expected. The next period set in prematurely, at the time when the leucorrhoea used to appear, but painless. There was still headache, but the blood was not offensive. The prescription was repeated. The following periods were normal. Headache only occasionally, but no more vomiting.-IBID.

Zinc Phosphid.x in Headache.-A lady in perfect health prepared a long report for a society and read it to a large audience without undue excitement. The next day she was distressed by the following Clinical Symptoms: Severe pressure in the back of the head, extending to the cervical spine, for four or five days. Feeling of fatigue, with a disinclination for any mental exertion. Remarks: A few doses relieved her completely and permanently.--DR. J. G. BALDWIN.

Phosphorus 200 plus in Chronic Diarrhea.-Over ten years ago I purchased a half-ounce vial of Boericke & Tafel's medicated globules, phos. 200. From these I have made successive potencies, as occasion required, and have since used no other preparation of this drug.

Mr. F.S. contracted chronic diarrhoea in Georgia; failed to obtain relief from a physician and two hospitals. He reached home September 2, 1896, extremely emaciated, very weak and scarcely able to speak above a whisper; was having, every twenty-four hours, twenty or twenty-five painless, copious, light-colored stools. He seemed to me to have intestinal tuberculosis.

I ordered an exclusive diet of boiled milk and gave phos. 200 plus a dose after each stool. This seeming to have no effect, I prescribed once calc. carb, 200; no change following, I again gave phosphorus, and improvement began at once. By September 12 he was having one or two normal stools a day.

In the latter part of September I sent him to his native air (Monmouth County, N. J.), where he promptly improved, gaining weight, a pound a day. Several months later he stated that he had fully recovered his health.-NATHAN NUTTING, M. D., Mt. Vernon, N. Y.

Berberis Vulgaris in Eczema Intertrigo.-In right groin; of over ten years standing. History showed cystic trouble at other periods. Pathogenetic Symptoms: Changing rheumatic pains in back, hips.

knees, ankles, wrists and tibia. Constant burning and itching in the eczematous spots. Clinical Symptoms: Cold knees.-DR. W. S. TALCOTT.

Duboisins in Hyperæmia of Optic Nerve.-Mrs. E. W., aged 21, applied for treatment at my clinic at the New York Ophthalmic Hospital on March 23, 1897. Examination revealed a low degree of hyperopic astigmia, which was corrected with a +0.25 D. cyl., axis 90°, and an hyperæmia of the right optic nerve. Pathogenetic Symptoms: Optic nerve red, and its outlines indistinct. Retinal veins tortuous and enlarged. Accommodative asthenopia. Clinical Symptoms: The appearance of a red object in the field of vision which moved with the movements of the eye. Remarks: Duboisin3 was prescribed every three hours, and the proper glasses ordered. On her next visit, April 8, she was completely cured, and the nerve appeared normal. Attention is called to the disappearance of the symptom, "the floating red spot.”—DR. C. H. HELFRICH.

Gelsimium sempervirens in Adenoiditis et Tonsilitis.-Boy, aged 10, had recurrent attacks of acute adenoiditis every two or three weeks. Inflammation would spread from the adenoid tissue in the pharyngeal vault down along the posterior pillars, culminating in an attack of tonsilitis follicularis. Tonsils not much swollen. Small white dots in openings of crypts, and mucous membrane bright red. Pathogenetic Symptoms: Deep flush on cheeks. Tongue coated yellowish white. Fetid breath. As the condition subsides there is a profuse flow of light-colored urine. Clinical Symptoms: Pain in throat relieved by cold drinks. Inflammation seems to be caused by nervous excitement more often than anything else. Remarks: A number of drugs were given without success. since then only one attack in three months.-DR. W. S. PEARSALL. Finally Gels., and

Ignatia in Chronic Diarrhea.—Mr. P., aged 54, had a diarrhoea during July and August. Aloes seemed to be indicaated, and would relieve for only a few days. Later it was discovered that the following pathogenetic symptoms were present: Pathogenetic Symptoms: Sticking pains in right temple. Dull pains, especially right side of head. Relaxed feeling in stomach and intestines. Rumbling in abdomen. Griping pains. with difficult passage of soft stool; the urging remains after stool. Ineffectual urging to stool. Urging, Aggravation A. M., and from coffee. Remarks: Complete relief of the symptoms in a few days.-Ibid.

Silica 30 in Otorrhoea.—A child, aged 4, had a discharge from ears from early infancy; first the right, but latterly the left. Pathogenetic Symptoms: Blephantis agglutinating eyelids in the morning. Clinical Symptoms: Discharge thick, white, profuse; at times yellow and watery, always bland. Temper irritable, but quiet.-DR. TALCOTT.

THE ACTIVE PRINCIPLE OF ERGOT.-Jacobi has determined the active principle of ergot of rye to be a resin which he names sphacelotoxine. It is in combination with a non-nitrogenous body not yet described, of golden yellow color and which is neither acid nor base, and termed ergochrysine.

Sphacelotoxine in the free state is readily decomposed, but is permanent when in combination with ergochrysine, such combination being named chrysotoxine. Arch. f. exp. Pathol. u. Pharmakologie, Bd. 29.

THE POISON OF THE HONEY-BEE.-Dr. Langer has examined the poison of the honey-bee in search for its active principle. He used in his investigations 25,000 bees.

The freshly discharged drop of poison is transparent and colorless, of acid re-action and bitter taste and has a fine aromatic odor well brought out by rubbing it between the fingers. When dried at 212° F. there is left gummy residue. The specific gravity is 1131. It is clearly soluble in water, but with alcohol it forms at first an emulsion, while continued action causes a granular precipitate.

Formic acid is readily shown to exist in the poison, but the real active principle is not this acid, but rather an organic base which in the free state is only soluble with difficulty in water and is held in solution in the poison by means of an acid. The composition of the active principle was not determined, owing to scarcity of the material. Ibid. Bd. 38. O.'C.

LOSS OF THE PHARYNGEAL REFLEX AND ITS RELATION TO HYSTERIA.—The majority of authors hold that the absence of the pharyngeal reflex so often seen in the hysterical is due to anæthesia of the pharyngeal mucous membrane, while Leube ascribes it to disturbance in the reflex arc without loss of sensibility. Kattwinkel has tested the matter in 100 cases of hysteria. In all the pharyngeal reflex was absent, but full sensibility of the mucous membrane was present in all but a few of the cascs. The absence of this reflex may

thus be considered one of the stigmata of hysteria. Neurolog. Centralbl., 21, 1897.

A RARELY SEEN COMPLICATION OF ACUTE ARTICULAR RHEUMATISM.-F. Steiner reports the appearance of thirty-five cases of articular rheumatism, of multiple neuritis or perineuritis of different nerve trunks. The neuritis ran parallel to the joint affection or else appeared most predominantly, the affected points being painful, but not swollen.

The affected nerve trunks were usually in the limb whose joints were affected, but at times were in limbs not thus diseased.

S. considers the process to be a perineuritis. The affection of the nerves was determined by the sensitiveness of the nerve trunks to pressure as well as by the subjective pain sensation.

This perineuritic complication of articular rheumatism was independent of the age or constitution of the patient, yet it seemed to be more frequently seen in women than in men. It occurred in slight as well as severe cases of articular rheumatism and in the beginning of the latter or at its height or during its disappearance. Deutsches Archiv. f. klin. Medicin, Bd. LVIII.

NEUROLOGY.

OPTIC NERVE ATROPHY FOLLOWING IODOFORM TREATMENT.Terson has reported to the Société de Biologie the case of a woman, aged 48, with burns on the thighs and arms. She was treated by the external application of iodoform. Three weeks later, without any of the symptoms of iodoform poisoning, there followed amblyopia. Ophthalomoscopic examination showing partial atrophy of both optic nerves with all the characters of toxic atrophy. Terson believes the atrophy to be chargeable to idodoform poisoning, although after burns marked changes in the eye-fundus, even atrophy, have occurred; in such cases, however, the changes are always inflammatory in character, which in the present case was wholly wanting. Berlin klin. Wochensch., 47, 1897.

UNUSUAL SYMPTOMS ACCOMPANYING ORGANIC CEREBRAL HEMIANESTHESIA. Dr. J. Chelchowski reports four cases of organic hemiplegia or hemiparesis in which with complete hemianæsthesia for ordinary sensorial and painful impressions of moderate intensity, as well as complete loss of the muscular sense there were present peculiar changes of sensibility to strong impressions. Very strong irritation as by deep puncture with a needle, hot water (107.6° -122°F.), ice, and even strong pressure causing pain upon the paralytic anaesthetic side.

The pain appeared a few seconds after the application, was very intense, lasted some minutes and during it later applications even when severe were not perceived on either side of the body. The pain was erroneously ascribed by the patient to some internal cause and was often erroneously located. Neurolog. Centralbl., 22, 1897.