Bastianelli's rule has been considered a good one-when para-sites are present quinin should be administered; when absent it should be withheld. This, I do not now feel inclined to accept. In a large majority of the cases of my series no parasites were present. This is in accord with the experience of Stephens and Christopher and of almost all observers who have studied the blood in this condition. These gentlemen think that the absence of the parasites may be accounted for by the usual administration of quinin before the attack. This is true, but I have seen the parasites disappear in cases which had no quinin previously. A case of double (spring) tertian, which had no quinin previously, developed hemoglobinuria which lasted about thirty hours. No antiperiodic was administered during attack. The parasites and fever disappeared after the sporulation of the second group of parasites. Here is a spread from the case in the practice of Dr. Gray (exhibiting). It contains estivo - autumnal parasites, spread taken about four hours after onset of black water. No antiperiodics were administered. Black water and fever subsided after about thirty hours.

Following Bastianelli's rule in two of my cases in which parasites were present, the administration of quinin was followed by a distinct exacerbation in the symptoms.

In closing, I must again express to you my appreciation of the honor you have conferred upon me in inviting me to address you, and thank you for the kind consideration which you have accorded my paper.

Owing to the late hour after the discussion of Dr. McElroy's paper, Dr. Jelks made a request of the president to allow him to postpone the reading of his paper to a later meeting, which was granted.

Dr. Ellett reported A Case of Papilloma of Nasal Septum, showing section of specimen removed, stating that Dr. Richmond McKinney had reported a similar case in the New York Medical Journal about three years ago, this being at the time about the fourteenth case on record.

Discussed by Dr. McKinney.

In the absence of Dr. J. L. Andrews, Dr. Barton made.

report of credential committee, reporting favorably upon the name of Dr. Cummings Harris, who was unanimously elected. Dr. Burns made report of special committee appointed at last meeting to revise constitution and by-laws.

Dr. Jelks moved that the Memphis and Shelby County Medical Society invite the Mississippi Valley Medical Association to hold its next annual meeting here in October, 1902. Discussed by Drs. Frank Jones, McKinney, Ellett and Burns. Carried.

Regular meeting, Tuesday evening, October 2, 1902.

The President, Dr. Alfred Moore, in the chair. Present were Drs. Barton, Battle Malone, Burns, Bell, A. B. Williams, Morrow, Black, Hall, Harris, Van Horn, Smythe, Frank Jones, Michie, Ellett, Rudisill, Turner, Ham, and McCown.

Visitors-Dr. J. L. McGehee and Dr. W. P. Yerger. The minutes of the last meeting were read and approved. Dr. Burns presented an interesting case of lichen planus, and it was discussed by Drs. Battle Malone and Smythe.

Dr. Barton read the names of J. L. McGehee and W. H. Baldwin as applicants for membership.

Dr. Burns, chairman of the committee appointed to revise the constition and by-laws so as to conform to the new coustitution and by-laws suggested by the American Medical Association, presented the report, which was adopted after some discussion.

BOOK REVIEWS.

THE DISEASES OF INFANCY AND CHILDHOOD, By L. Emmett Holt, A.M., M.D., Professor of Diseases of Children in the College of Physicians and Surgeons (Columbia University); Consulting Physician to the New York Infant Asylum, and to the Hospital for Ruptured and Crippled. Second edition, revised and enlarged, with 225 illustrations, including nine colored plates. Sold only by subscription. Prices, cloth, $6.00; half leather, $6.50. D. Appleton & Co., 436 Fifth Avenue, New York.

It is with genuine pleasure that we welcome the second edition of Holt's monumental work on the diseases of infancy and childhood. There is no contribution to the literature of this subject, be it foreign or domestic, which has done more toward placing this study on the plane of scientific accuracy.

It is the outcome of twenty odd years of experience in private and hospital practice to which this book may be ascribed, and the inherent capability of the

author is emphasized on every page of the book. In a clear and simple style, Dr. Holt has consecutively considered the various diseased conditions to which the child may fall a victim, and presents a thorough exposition of every feature of the diagnosis and care of these cases that the practitioner may desire enlightenment upon. Special attention is paid to the diseases of the newly born child, nutrition, its derangements and diseases, the acute diseases of the lungs and intestinal tract, and the specific infectious diseases. To this last section more than two hundred pages have been devoted, fifty of these being accorded the subject of diphtheria. Splendid illustrations, beautiful printing, and otherwise complete to the extreme of thoroughness, this work will continue to add to its host of friends in the profession.

A TEXT-BOOK ON DISEASES OF INFANCY AND CHILDHOOD. For the use of Students and Practitioners. By Henry Koplik, M.D., Attending Pediatrist to Mt. Sinai Hospital, New York; ex-President of American Pediatric Society, etc. Octavo, 675 pages, 169 engravings and 30 plates in colors and monochrome. Cloth, $5.00, net; leather, $6.00, net.

Since the name of Koplik is already more than well known for his contributions to the development of the study of the diseases of infancy and childhood, a textbook devoted to this subject from his pen will meet with a cordial welcome from the medical profession, and this welcome will be deserved, for in this book he has added to the supply of text-books on this subject a work that will not find oblivion on account of its lack of originality.

The author has availed himself of the luxuriant production of pediatric literature existing on both sides of the Atlantic in various languages, and has gathered and unified the world's best practice in a systematic and condensed volume. But in doing this, he does not lose his individuality, but inspires the reader with his own valuable experience and careful judgment in a comparison of the value of the work of other pediatrists.

Koplik has given exhaustive consideration to the methods of examination and physical diagnosis, the subject of infant feeding, the chapters on diseases of the lungs, stomach, intestines and heart. Every other detail connected with this field has similarly received full and attractive treatment, and the volume throughout maintains a clinical and practical tone. Illustrations abound.

We shall look to see Koplik's work attain importance among text-books on pediatrics.

A TEXT-BOOK OF HISTOLOGY, By Dr. Ladislaus Szymonowicz, Professor of Histology and Embryology in the University of Lemberg. Translated by John B. MacCallum, M.D., Johns Hopkins Medical School, Baltimore. Octavo, 437 pages, 277 illustrations, including 57 full-page plates in colors and monochrome. Cloth, $4.75, net. Lea Brothers & Co., Philadelphia and New York. 1902.

The development of the science of histology is due largely to the efforts of the Germans, for with their painstaking persistence they have succeeded in bringing out the minutiae of the microscopic construction of tissues that could hardly have been attained by a less laborious nation of investigators.

Among histologists in Germany, Szymonowicz is preeminent, and his work on histology is a monument to his efforts. It is beautifully illustrated, and very clear in its descriptions of technique. In preparing the book for the needs of American students, Dr. MacCallum has added many desirable points, and has also further enriched its series of engravings and colored plates.

I WOULD be remiss in my duty and callous to an innate sense of gratitude if I did not embrace this opportunity to express my appreciation of the distinguished honor which you have conferred upon me. Under the guidance of your efficient secretary, the Tri-State Medical Association of Mississippi, Arkansas and Tennessee shines as a star of the first magnitude in the galaxy of medical societies. You have acquired a reputation far and near for the high character and thoroughness of your work, which you well merit. In expressing the hope that this meeting shall be no exception to your past record, I bespeak your hearty coöperation in my endeavor to discharge, in an impartial manner, the executive duties incumbent upon me.

The time allotted to these remarks would not permit me to even sketch an outline of the history of medicine. I think we can get no clearer and more beautiful view of it than to behold the picture which Baas presents. He says: "Medical science on the whole as regards its various phases and epochs of development, may be likened to a large picture, whose

* President's Address, delivered before the Tri-State Medical Association of Mississippi, Arkansas and Tennessee, Nineteenth Annual Meeting, Memphis, November 11-13, 1902.

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atmosphere, tinted by unmeasured distance, displays only a few clearer cloud forms in somewhat definite outlines and masses, while the limited background exhibits in perspective lofty temples, about whose portals wander priests in ample mantles to guard them from the entrance of the uncalled. On either side appear mighty crags and groups of lofty trees, whose foliage is penetrated by the powerful rays of the noonday sun, while the foreground greets us in undimmed brilliancy and instinct with life. To the distant sky, with its cloudy forms, we may compare the mythical era of medicine with its storied gods and demigods of punishment and healing. To the background, the cognate priestly era, with its sacerdotal physicians and theurgic medicine, and its works hallowed by faith. The middle ground may be likened to the union of the terrestrial and celestial philosophy with medicine, the philosophic period; and finally, the clear foreground, to the scientific period with its practical principles and ideas."

At the risk of marring this picture, I would erect in the foreground a temple of science, and incidentally note the influence of the thought of the time upon its construction. It is true, as Dr. Holmes says: "Medicine is as sensitive to outside influences, political, religious, philosophical, imaginative, as is the barometer to the changes of atmospheric density." So it was while Columbus and other adventurers were exploring unknown seas and opening new continents; while Copernicus was exploring the heavens and discovering the true system of the universe; while Martin Luther was breaking through old traditions leading men out into the freedom of truth; Andreas Vesalus, refusing to believe that the narrow trousers of his contemporaries could overcome the strong curvature of the thigh bones which Galen described, was securing and promulgating facts which are the pillars upon which our temple rests.

Harvey, catching the spirit of the Elizabethan period, gave to the world the first fruits of the reformation. The field of inductive-experimental physiology lay fallow for almost a century after Harvey. Not until after Newton had discovered the law of gravitation and had given to the world his Principia, did Haller, in Germany, lay the foundation of modern experimen