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by J. C. Morse; Horsemanship, by H. C. Merwin; Rowing, by Benjamin Garno; Canoeing, by C. Bowyer Vaux; a collection of authoritative articles on healthful outdoor pleasures, illustrated by Copeland, Beals, Gallagher, Young, and Shute. This book, published by the Pope M'fg Co., of Boston, for the benefit of the Columbia bicycle, contains articles without any advertising in them. Sent by mail to anybody for five two-cent stamps.

THE INTERNATIONAL MEDICAL ANNUAL and Practitioner's Index for 1893. Edited by a corps of thirty-eight department editors-European and American-specialists in their several departments. P. W. Williams, M D., Secretary of Staff. 626 octavo pages. Illustrated. $2.75. E. B. Treat, Publisher, 5 Cooper Union, New York.

The eleventh yearly issue of this valuable one-volume reference work perpetuates the enviable reputation which its predecessors have made for selection of material, accuracy of statement, and great usefulness. The corps of department editors is representative in every respect. Numerous illustrationsmany of which are in colors-make the "Annual" more than ever welcome to the profession, as providing, at a reasonable outlay, the handiest and best resumé of medical progress yet offered. Part I comprises the New Remedies, together with an extended Review of the Therapeutic Progress of the Year; Part II, the major portion of the book, is given to the consideration of New Treatment, and is a retrospect of the year's work, with several original articles by eminent authorities; Part III is made up of miscellaneous articles of great interest to the profession. The work is alphabetical, although a complete Index is given. Such an "Annual" serves to keep the practitioner abreast of the times with reference to the medical literature of the world.

PAMPHLETS RECEIVED.

'Spondylitis of Second Cervical Vertebra.' By Reginald H. Sayre, M. D., New York. 'Trachomo.' By Jules Mutermilch, M. D. Translated by L. Webster Fox, M. D., Philadelphia.

'Annual Address before the State Board of Health of Pennsylvania.' By Samuel G. Dixon, M. D., Philadelphia.

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'Some Points in Reference to the Inflammations of Cartilage.' Address of the President, Benjamin Lee, M. D., Philadelphia.

'Descriptive Sketch and Drawings of two Cases of Symmetrically Placed Opacities of the Cornea, occurring in Mother and Son.' By Charles A. Oliver, M. D., Philadelphia.

'Laws and Regulations for the Maritime Quarantines of the United States.' Washington, 1893. 'Surgical Dressings, Aseptic and Antiseptic.' By Seward W. Williams, PH.C., F. C. S.

'Certificates of Death, their Significance, etc.' By P. C. Remondino, M. D., San Diego, Cal. 'Symphysiotomy versus its Substitute.' By Charles P. Noble, M. D., Philadelphia.

O Certain Problems in Abdominal Surgery, based on 100 Cœliotomies.' By Charles P. Noble, M.D. 'Points in Office Practice in the Treatment of the Diseases of Women.' By Charles P. Noble, M.D.

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day-is said to be efficacious even in the obstinate vomiting of pregnancy.

-For IRRITABLE COUGH, a writer in the
Practitioner suggests:-

B. Acidi hydrocyanici diluti, fz iss
Morphinæ acetatis,

Mucilaginis acacia,

Syrupi pruni virginianæ,
Aquam ad

Misce et fiat mistura.

gr. iss

fiv
3 vj.

A teaspoonful to be sipped every four or six hours.

-Rossolo (Annales d'Orthopédie, in The Therap. Gazette) warmly recommends chrysarobin in the form of suppository in the treatment of HEMORRHOIDS, made as follows:

R. Chrysarobin,

Ol. theobromæ,

Iodoform.,

Extract. belladonnæ,

gr. j
gr. xxx
gr.

gr. fo.

:

M.

-For MEMBRANOUS ENTERITIS, DujardinBeaumetz (Jour. de Méd., in Med. News,

April 29) suggests :

R. Salol,

Benzo-naphthol,

Sodii bicarb.,

Fiant cachets xxiv.

aa

3 ij.

M.

Sig. One after each meal.

A quart of a ten or twenty per cent. solution of naphthol in warm water is also injected daily.

For the NIGHT-SWEATS OF PULMONARY
TUBERCULOSIS Dr. Ewart (La Semaine Méd.
in Med. News,) suggests:-
R. Quininæ sulphat.,
Zinci sulphat,

Ext. hyoscyami,

Ext. nucis vomicæ,

Ft. pil. j.

ää gr. ij
gr.j

gr. }.

S.-Take at bedtime.

M.

cases of malarial intoxication of long dura-
tion, in which ANEMIA has been marked and
in which, after cessation of acute symptoms, a
course of arsenic has failed to bring about
marked improvement, rapid return of cor-
puscle and hemoglobin to an approximately
normal standard has followed the administra-
tion of a solution prepared as follows:-
B. Tincture of ferric chloride, fzij
Diluted phosphoric acid, f3 iij
Glycerin,
f3 vj

Solution of hydrogen diox

ide, enough to make f3iij.

SIG. Two teaspoonfuls in three ounces of water before meals thrice daily.

This is slightly modified from a formula of B. W. Richardson's. It will be practically, stable for the few days during which the three-ounce mixture lasts. It is useful in chlorosis and anæmias generally.

-Dr. Edward J. Bermingham (N. Y. M. Journal, Feb. 4th), Surgeon to the New York Throat and Nose Infirmary, describes a very ingenious apparatus which he has devised for controlling the Edison current so that it can be used direct for GALVANO CAUTERY OPERATIONS. The apparatus consists of a rheostat, made of coils of iron wire and a handle. The peculiarity of the handle consists of its having solid conductors, and the circuit is therefore always closed. It is under the control of the operator's thumb at all times during the operation, and the current can be cut off from, or allowed to pass to, the

For an EMULSION OF COD-LIVER OIL knife instantaneously and without producing

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an arc. The apparatus is simple and inexpensive, and, from the detailed description given, any electrician can construct it. Dr. Bermingham has been using it for two years. and a half for all his cautery operations.

-TREATMENT OF FOLLICULAR TONSILLITIS.-Dr. J. C. Hoag (Chicago Med. Recorder, April) recommends removing the exudate of the tonsils in cases of acute follicular tonsillitis. This he does with a small spoon, a probe wrapped in cotton, dipped in peroxide of hydrogen, and a small pair of forceps. He finds that the removal of the cheesy plugs from the lacunæ and follicles is uniformly followed by a very marked amelio

ration of all the symptoms of the disease, and believes that in this way the source of the constitutional disturbance is attacked. He uses a gargle of peroxide of hydrogen.

-A one to five per cent. solution of styrone (which is a compound of styrax and balsam

of Peru) in alcohol is recommended in CHRONIC INFLAMMATION OF THE MIDDLE EAR (Archives of Otology). Dr. Spalding recommends it as specially useful in perforations of Shrapnell's membrane. He applies it

on a small cotton swab after having had the ear thoroughly cleansed by syringing, and from results obtained he thinks that it merits a trial.

-Dr. W. E. Putnam, of Whiting, Ind., writes to Med. Record, April 15, as follows: "I wish to make known a plan of treatment in DIPHTHERIA which I have just carried out successfully in the case of my own children, aged two, four, and five years respectively. I used a spray of peroxide of hydrogen, full strength, to which I added one part per thousand of corrosive sublimate. I reasoned

has been giving remarkably good results. Losophan is a triiodocresol, very rich in iodine (about 80 per cent.) with which, on application to dermatic lesions, it slowly parts, thus avoiding toxic effects, while making the pathological field untenable for living organisms. For these reasons, Losophan is indicated in all cutaneous conditions due to the development of the trycophyton fungus, in mycosis, pityriasis, sycosis, prurigo, pediculosis, and in all of the large groups of skin diseases due to the presence of filamentous fungi or microspores. The clinical reports advise the use of Losophan in one to two per cent. ointments with lanolin or vaselin. Where a wash is needed, a solution should be made of one or two parts of Losophan in a mixture of 25 parts of water with 75 parts of alcohol. The mixture keeps well. Losophan has already been tested in the treatment of phimosis and chancre. The best results were gained from a one per cent. powder, dusted over the lesions.

-Shoemaker (Materia Medica and Therathat if others can give one-half grain of sub-peutics) recommends PAPAIN in DYSPEPSIA

limate a day internally, I can use a grain a day in my atomizer, knowing that the child will spit out nine-tenths of it. I also used a little oil stove, a tin tea-kettle, and a piece of hose three feet long. In the kettle I put turpentine and lime water, in the proportion of a tablespoonful to a pint, and then steamed the child, placing the end of the hose six or eight inches from his mouth."

-Prof. W. W. Keen corrects a statement in the Medical News, of April 22, in which Dr. Allen Starr mentioned that "craniotomy had apparently been undertaken without regard to age. Keen operated on a patient aged nineteen years," etc. He writes that the oldest patient he had ever operated on was six and one-half years of age, and that he had uniformly declined to operate on any child over seven years old. It had always seemed to him unwise to perform such operations on any patient except in early childhood. -In recent treatment of tinea tonsurans

as follows:

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-Drs. Biesenthal and Schmidt review (Berliner Klinische Wochenschrift in Thera. Gazette) the clinical reports on PIPERAZIN which have appeared recently. The reports LOSOPHAN, a new and very active mycotic, of Vogt, Ebstein, Heubach, Krakauer, and

A

PIPERAZIN

URIC ACID SOLVENT

BOUT two years ago the Chemische Fabrik auf Actien, vormals E. Schering, of Berlin, after long experimenting in its laboratory by its staff of chemists, produced a new chemical product, which at first seemed to be identical with spermine. Through clinical trials this supposition was quickly found to be erroneous, but further experiments developed the interesting fact that the new product was a uric acid solvent. This notable scientific discovery was achieved independently by the Schering laboratory, and it deserves the full credit for enriching materia medica with so valuable a new therapeutic agent.

The name "Piperazin" was adopted for the product, and Piperazin (Schering) has in two years become widely known to the medical profession throughout the world as the most powerful uric acid solvent known. Scores of clinical reports by the highest authorities, among them such names as BARDET, BISENTHAL, VON MERING, SCHWENNINGER, VOGT, EBSTEIN, D. D. STEWART, and J. H. BRADFORD (the last two of Philadelphia), have been published in the leading medical journals of the world; and all these reports were based solely on the use of the Piperazin made by Schering.

Now, recently, a German manufacturing firm which furnishes a number of other new remedies, has claimed to have discovered a new process yielding a product which they claim is identical with the Piperazin made by Schering; and without waiting to give their product thorough clinical trial they and their agents are making the attempt to sell the untried product. With reprehensible enterprise they appropriated all the literature based on Schering's Piperazin for their own advertising purposes, and with other questionable methods, such as tempting by lower price, they bolster up their claim and bid for preference for their product.

Aside from the fact that this firm has no moral right to appropriate for its own profit the legitimate property of the Schering laboratory, it exhibits superlative presumption in inviting the medical profession to use a product with which not a single clinical trial has been made or published as yet.

Caution:-To avoid the risk of failure with a substitute product of untried nature, and to ensure such favorable therapeutical effects as reported by all authorities to date, be sure to specify

"PIPERAZIN (SCHERING)."

Full descriptive pamphlet, giving chemical, physiological, and therapeutical data, together with authentic clinical reports

by authorities quoted above, will be mailed to physicians, free, on request.

Sole Agents in U. S.: LEHN & FINK, NEW YORK.

Definite Chemical Products

OF SUPERIOR THERAPEUTIC VALUE.

SALIPYRIN RIEDEL).

ANALGESIC, ANTI-RHEUMATIC, ANTIPYRETIC. A chemical combination of 57.7 per cent. anti-
pyrine, and 42.3 per cent. salicylic acid. Dose, to 2 grammes. Free from cardiac influence and other
unpleasant side and after effects. Used with marked success in Influenza, Neuralgia, and all Rheu

matic affections.

THIOL (RIEDEL).

A synthetically-produced body, chemically and therapeutically identical with ICHTHYOL, and superior
in being odorless and non-toxic. Supplied in powder and liquid form. Circular reprint of clinical
report sent on request.

LYSOL.

"THE IDEAL DISINFECTANT."

The latest and most perfect of the cresol-derivative antiseptic and

disinfectant agents. A 16-page monograph mailed on request.

PIPERAZIN (SCHERING).

URIC ACID SOLVENT. Will dissolve at least twelve times more uric acid than lithia. Dose, 15
grains per day, with continuous treatment. Pamphlet (32 pages) sent on request.

PHENOCOLL (SCHERING).

ANTIPYRETIC, ANTI-RHEUMATIC, ANALGESIC, NERVINE. "The superior of all conl-tar anti-
pyretics previously introduced. Dose, 7% to 15 grains. Descriptive pamphlet (40 pages) supplied on
request.

CHLORALAMID (SCHERING).

HYPNOTIC.-Dose, 15 to 45 Grains. A full descriptive pamphlet (64 pages) supplied on request. Physicians are invited to write us whenever desirous of obtaining information regarding any new remedies. We will promptly answer all such inquiries.

A Sample Copy of "NOTES ON NEW REMEDIES" malled on request.

LEHN & FINK,

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