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The Rigid Os. We all know how very trying it is to the physician, to say nothing of the unfortunate patient, who after some hours of suffering from labor pains finds herself tired and greatly exhausted, because of a rigid os. This condition is frequently encountered by all obstetricians, and unless relieved. prolongs labor and depletes the vitality of the patient. In these cases H. Marion Sims, M.D., used Hayden's Viburnum Compound with good success, and if this eminent practitioner so readily endorses H. V. C. we have no hesitancy in freely recommending its use in the above condition.

Always Has Cood Results." My first experience with Neurilla in a case of Nurasthenia, and I have since continued its use and always with good results."-William H. Hill, Baltimore, Md.

Pepto-Mangan. "Permit me to say that the supply of PeptoMangan (Gude) which you kindly sent to me has been employed in a case of chlorosis, in which I had previously administered a number of other iron preparations, without any material benefit. After the use of your preparation I was able to note a remarkable improvement."-Dr. Gustav Bondy, Vienna.

Tongaline:-In Tongaline & Quinine Tablets the laxative and cathartic effects of Tongaline, combined with the anti-malarial and anti-periodic action of quinine, give a most reliable and effective prescription for diseases that have periodicity as a prominent feature, accompanied by rheumatic or neuralgic conditions.

Gastralgia-Its Treatment.-Gastralgia is, for therapeutical purposes, divided into two groups by Professor Saundby (N. Y. Medical Journal). The first group comprises those cases in which pain occurs independently of eating, and the second group, those cases in which the pain occurs after food is taken. The treatment of the first class consists of change of scene, a voyage or mountain air, abundant food at regular intervals. The palliative treatment consists of iron, quinine, arsenic, nux vomica and the mineral acids. For the second class, the treatment is, rest in bed, milk and lime water in sufficient quantities—say an ounce every hour. A nutrient enema of one egg, beaten up in four ounces of milk, to be given. every four hours. The amount of milk should be increased with improvement, and if milk fails, from two to three ounces of lightly

cooked minced meat may be substituted. For the relief of the pain in both cases, Saundby gives morphia or heroin, but in a recent clinical report Professor Boone, College of Physicians and Surgeans, St. Louis, states that he finds one Antikamnia and Heroin Tablet (5 grains Antikamnia; 1-12th grain Heroin Hydrochloride) given as required, not only relieves the pain, but prevents its recurrence, much more satisfactorily than either heroin or morphine alone. In other respects he concurs with Professor Saundby in his method of treatment.

Chionia. I am not in the habit of writing promiscuously of the virtues of medicines, but when I have used a remedy for many years with uniform success I feel that it is not out of place to give that remedy my commendation. I have been engaged in the practice of medicine here for many years and the diseases which I am called upon to treat are mostly of malarial origin. Under such circumstances I am required to have a positive and efficient tonic for the hepatic organs. It is very difficulty for me to get along without that tried and true remedy for the above conditions, Chionia. I frequently use it alone and at other times in combination with other indicated remedies. I find it a real tonic for liver troubles and not a meres timulant, that its administration promotes digestion and supplies the exhausted and run-down liver with new energy. Another great advantage is that it has no depressing effects which ordinary purgatives possess."-L. Williams, M.D., Yorktown, Ark.

The Abuse of the Curette.-Dr V. P. Valentine, Professor of Diseases of Women in the Dallas University, presents in the April issue of the Texas News a most able and instructive article under the above caption. Among the many excellent suggestions he says: "Three very important pus-producing germs are frequently introduced into the genital tract; staphylococcus, streptococcus and gonococcus. Of these, the last being the least virulent and the first one containing the greatest danger, as long as a simple sapraemia exists, that is, as long as putrefactive action is contained within an envelope and has not yet invaded the living cells, it may be possible to get it without breaking down the breast works or fortifications that nature has thrown up. It is demonstrable that as soon as nature has any cause to fear an invasion by the foe, she calls out her standing army; the leucocytes begin preparing for war; they close up the fimbriated ends of the tubes, lymph is thrown out, plastic material is formed and nature rallies all her forces to repel the invaders. Now we go in with the curette and tear away these fortifications, and the hordes of bacteria over-run nature with their countless millions, so that we have instead of a mere intoxication, an invasion of lining tissue, and every current of the lody,

both lymph and blood, running bank full of pus-producing microorganisms with their toxins, and general sepsis is the result." these conditions he points out that medication is indicated to destroy the germs and not facilitate the migration by curetting. He also states: "Rather than curette in cases of doubt, it is infinftely better to employ medication." Experience and clinical investigation has demonstrated that in cases of inflammation, due to the presence of one or more of these pus-producing germs, Micajah's Medicated Uterine Wafers act most satisfactorily. The pronounced antiseptic and bactericidal properties of this remedy should induce its use in cases where a Curette might seem called for, and as a Medication it meets all of the requirements as suggested in the condition mentioned by Professor Valentine where a local application is indicated.

Success and Gratitude.-We beg to gracefully announte to the Medical Profession the removal of our office and laboratories to 105 Chambers St., New York, N. Y., where with greater space and more extensive facilities we shall be better enabled to take care of the increasing demand for Ergoapiol (Smith) and Glyco-Heroin (Smith). After having our personal statements as to the unusual efficacy of these preparations in their respective indications verified by hospital and clinical investigations, we sought to interest the physicians individually, and the satisfaction of those who have investigated either or both could not be more fully manifested than in the necessity of our new and more commodious quorters. Indeed, none the less is our gratitude to the DENVER MEDICAL TIMES, which has been so frequently mentioned in the communications requesting trial samples etc., therein showing the large and wide-spread circulation of so consummate and estimable a Journal. Martin H. Smith Co.

"Of Aletris Cordial I cannot speak too highly. Hardly a day. passes that I do not prescribe it. As a uterine tonic and female regulator, it surpasses everything in use. In prolapsus uteri, caused by weakness and relaxation, Aletris Cordial internally in conjunction with S. H. Kennedy's Extract of Pinus Canadensis, as a vaginal injection, has worked wonders in my hands. I will note one of many cases: August 19th, Mrs. H., age 45, married 20 years, no children. Procidentia of uterus, accompanied with offensive leucorrhea. We placed her in knee and chest position, and reduced the uterus. Applied a sponge pessary to retain it in place. Gave Aletris Cordial, a teaspoonful to be taken three times daily. S. H. Kennedy's Extract of Pinus Canadensis (Dark), a teaspoonful to be used in one-half pint of warm water, as a vaginal injection. Two injections were to be used daily, patient to assume a prone

position, and retain injections for five or ten minutes each time.

Ordered her to report in two weeks. September 23, she came back much improved in general health. Uterus has given no trouble since being reduced. Notwithstanding the fact that the sponge was removed, washed and replaced at the time of each injection, it had become very foul, consequently it was discarded, and one of Dr. Herricks silver stem pessaries adjusted in its place. This was to be removed by the patient. She was to continue treatment same as before, and report again in two weeks. September 19 she again. reported, and said she felt as well as she ever did in her life. Removed pessary; uterus reduced to normal size. She took in all about two bottles of Aletris Cordial, and used nearly one bottle of S. H. Kennedy's Extract of Pinus Canadensis. It has now benn over two years since I treated her for uterine trouble, and she remains perfectly well.”—A. S. Martin, M.D., Vicksburg, Mich.

Gastric Contents in Carcinoma.-Otto Reissner (quoted in Chicago Clinic) finds that the gastric contents in cases of cancer differ from cases of achylia and gastric atrophy by containing a large amount of the fixed chlorides. This indicates that the deficiency in hydrochloric acid in cancer cannot be due altogether to the atrophy of the mucous membrane produced by the new growth. Reissner claims that the neutralization of the acid is due to the action of an alkaline juice exuding from the cancer when in state of ulceration. The production of acid is also lessened in consequence of toxic action of this cancer juice.

Bacteriology of Acute Catarrhal Conjunctivitis:-In fifty normal conjunctivae examined by P. Chalmers Jameson (Brooklyn Medical Journal) the staphylococcus pyogenes aureus was found twice and the staphylococcus pyogenes albus or epidermis albus sixteen times. In a series of twenty-five cases of acute catarrhal conjunctivitis the staphylococcus albus was found in large quantity without exception as the predominating organism. The primary exciting cause of the disease, however, is conjunctival hyperemia, so common in large cities, from dust, smoke, strong wind, bright light, reflex ciliary strain and exposure to cold. The condition resulting from this vascular derangement is a change in the fluid constituent of the conjunctival sac by the outpouring of sanguineous exudate from its impaired vessels, so furnishing a suitable nidus for the rapid propagation of the organisms-staphylococcus epidermis albus principally-already existent in the sac.

We can't tell you

what drug to prescribe-it takes a doctor to know that.
The administration of medication falls within the province
of the physician-medical knowledge and professional ex-
perience are required for that.
But

We can tell you

that if your patient needs beef, iron, cinchona, and
brandy-each in its best and most assimilable form-then
"Colden's Liquid Beef Tonic" (Form. No. 1) is the
preparation to prescribe. If the ferruginous effect is not
desirable, we suggest that you employ "Ext. Carnis F1.
Comp. (Colden)" Prep. No. 2, without iron. We feel jus-
tified in assuring satisfaction and success because of the
results it has been giving for over a quarter of a century.

The CHARLES N. CRITTENTON CO.,
Sole Agents for the United States.

Laboratory: 115 and 117 Fulton Street, New York.
Samples sent free on application, to physicians.

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