zeese forbidden fruit.' Iv, she make one courtesy-ze snake, he fill her parasol wiz ze appel. He says: 'Eritis sicut Deus: Monsieur Adam, he vill eat ze appel, he vill become like one Dieu; know ze good and ze evil-but you, Madame Iv, can not become more of a goddess than you are now.' An' zat feenish Madame Iv."-The Railway Surgeon.

PILOCARPINE AS A PROPHYLACTIC.-C. Sziklai (Wien. med. Presse, 1895,) cites a few cases in support of his statement (see page 205 of the current volume of the "Bulletin ") that pilocarpine acts both as a specific and prophylactic in epidemic croup and in laryngitis, whether croupous or diphtheritic in its nature. In families with numerous children where one child took sick with croup or diphtheria he always succeeded in limiting the disease to that one child by administering this remedy to all the children, sick and well, and this, very often, in spite of very bad hygienic surroundings, with practically no isolation of the person infected.

When, however, the disease is once contracted, the remedy does not prevent its spreading in the person infected, although it much shortens the course of the disease.

In three cases of diphtheria the children were completely cured in from one to two weeks. In the case of laryngeal croup cited, the child was considered cured on the second day, but on the fourth day a second attack occurred, this time bronchial croup, which again was cured in two days by the administration of two 0.02-gram (one third grain) doses of pilocarpine; thirty-six hours after this second cure the symptoms of croupous pneumonia developed, which, however, were suppressed by the same treatment in less than three days.

The author employs pilocarpine hydrochlorate as a prophylactic in rather large doses. He prescribes it in a one-per-cent solution, of which he gives 10 minims (0.6 c. c.) three times daily to children a few years old, and only half that quantity to children of less than one year.

Dr. S. further states that pilocarpine hydrochlorate is employed by Dr. Kovacs in pneumonia, and that the disease is much shortened by the treatment.

THE TREATMENT OF ECTOPIC PREGNANCY WITH INJECTIONS OF MORPHINE. In the Section for Obstetrics and Gynecology of the recent Congress of German Naturalists and Physicians, Prochownick (Deutsche medicin. Wochenschr., 1895, No. 40, Suppl. No. 25, p. 170,) advocated the treatment of ectopic pregnancy during the first months by means of injections of morphine instead of by operation. He reported four cases successfully treated by a single injection through the vagina of from gr. 1⁄2 to gr. 34 of morphine into the intact gestation sac without aspiration. In three of the cases the pregnancy had not passed the twelfth week; in the remaining one, which was complicated by gonorrhea, this period had been passed, and in this case also an abscess formed that discharged through the rectum. In a

fifth case the injection was made through the anterior abdominal wall, and the sac was infected by the needle passing through an adherent loop of bowel; septicemia developed and celiotomy was required, but recovery ensued. It is important to refrain from aspiration and to make but a single injection. The operation is contra-indicated if the twelfth week has passed, if abortion is in process of occurrence, and if chronic gonorrhea or acute perimetritis exist. The vaginal is the only safe route of injection.-Medical New's.

NEW AND SPEEDY METHOD OF DILATING A RIGID OS IN PARTURITION. At a meeting of the Obstetrical Society of London, Dr. Farrar (Gainsborough) gave the details of two cases in which he had used a ten-per-cent solution of cocaine as an application to the rigid os. In one case he had applied the cocaine after endeavoring vainly to relax the cervix by means of chloral, bromide of potassium, and morphia, and the most persistent attempts at digital and mechanical dilatation, with and without chloroform. He decided upon incising the os, and used the cocaine to this end. After five minutes he introduced the finger as a guide to the scissors, and, to his surprise, found the os widely dilated. In the second case, a primipara, forty-eight years of age, he used every effort, as before, to produce relaxation, and waited three days before making the application of cocaine, which was immediately successful. In four minutes the os had yielded. He considered the dilatation to be due to the cocaine in both cases. Dr. Armand Routh said that Dr. Dibbs, of Shankin, had recommended cocaine as relieving the pains of the first stage of labor, and that Mr. Head Moore advised cocaine and boric acid pessaries in cases of rigid os. He himself had found it useful. The president, Dr. G. E. Herman, said that two cases were rather a slender foundation upon which to base a conclusion, but if Dr. Farrar's results were confirmed by further experience, he would have made a valuable addition to our obstetric resources.-The Lancet.

THE MICROBE OF SCURVY.-Testi and Beri (Gazz. degli Osped, August 10, 1895,) have succeeded in isolating from a piece of scorbutic gum a micro-organism which they believe to be the cause of scurvy. The microbe stains in all the aniline dyes resists Gram's stain, is perfectly round, and generally united with one or more of its kind. Its culture renders gelatine fluid, and gives rise to a sawdust like deposit. Inoculation of these cultures into guinea-pigs and rabbits gave rise to fever, and the necropsy showed hemorrhage stains in various parts of the body, and nodules of connective tissue, new formation. Experiments were made in four cases, and in three out of the four the above mentioned results were obtained; in the fourth case the authors attribute their negative results to the fact that the patient had improved considerably under treatment. The diplococci found by the authors differ considerably from any that are usually present in the oral cavity of man.-British Medical Journal.

THE LATEST ACHIEVEMENT IN PLASTIC SURGERY.-At the Charing Cross Hospital, London, Mr. J. Astley Bloxam, the senior surgeon, recently performed one of the most remarkable operations on record. It appears that a few months since a young man without a nose asked the authorities whether they could oubtain a real nose for him. To oblige the applicant an amputated finger of another patient was grafted onto his face, but it was found that the amputation had caused the finger to die. The noseless man, nothing daunted, then agreed to the surgeon's suggestions that one of his own (the patient's) fingers should be cut off to furnish the nasal organ. But in order that the finger should not be wasted in the event of the operation being unsuccessful, the patient's arm was encased in plaster, and for four weeks he had to hold his finger to his face in the hope of it taking root. This it did. The finger was then taken off the hand and now remains fixed as a nose. It has been manipulated so that it is no longer to be recognized as a finger, and the process of shaping it is being proceded with.

EMPYEMA IN CHILDREN.-I. When pus is found to be present in the pleural cavity, the proper treatment is to remove it. 2. The best method is simple incision and drainage. 3. The best site for the operation is the fifth space in the mid-axillary line. 4. Irrigation is unadvisable, and is indicated only in cases of fetid effusion. 5. Exploration and scraping of the cavity are not necessary. 6. Resection of the rib is practically never necessary in children as a primary procedure to procure efficient drainage, but may be required to secure the closure of the sinus, subsequently, by allowing the chest wall to fall in. 7. Collapse of the chest wall is not a result to be desired in the early stages of the treatment. 8. Rapid and complete expansion of the lung is the great object of treatment. 9. The tube must be removed early.-Cautlex; Medical Record.

ANTISTREPTOCOCCIN.-The New Remedies, September, gives a brief reference, from its foreign correspondence, to a new remedial serum bearing the name in the caption. It is the latest of the antitoxic serums. It has been developed and brought into the therapeutic field by Prof. Marmorek. "It is said to destroy the pathogenic streptococcus absolutely, and will therefore prove of inestimable value in conditions which are now usually abandoned as hopeless. The serum is injected in routine style and does not produce side or after effects." Marmorek is conducting clinical experiments which will be published as rapidly as consistent with reliability. Early reports thereon have been promised.

SEPTICEMIA.-The latest treatment for general septicemia is hypodermic injections of creosote. The creosote is mixed with equal parts of camphorated oil, and twenty minims of the solution are injected three times a day. Journal of Practical Medicine, October, 1895.

Special Notices.

SEXUAL NEURÆSTHENIA. In the course of an able paper, which appears in the November issue of the Medical Sentinel, Dr. David H. Rand, of Portland, Oregon, late secretary of the Genito-Urinary Section of the American Medical Association, etc., says: "In many of these sexual troubles, particularly where there is a nervous phase, the strictest attention must be given to the general condition of the patient. The bowels must be kept open and toned up, and good nutritious food administered. Some one of the artificial foods may be used with advantage, and I am specially well pleased with the new product, Paskola. It has given me great satisfaction where used in many cases." We earnestly recommend that physicians who have not tried this article take advantage of the manufacturers' liberal offer which appears elsewhere in our pages.

CHRONIC CYSTITIS WITH STRICTURE.-My experience with Sanmetto is quite extensive. I could give special cases in which its action was simply astonishing, but in this report I wish to summarize my experience by saying I have given Sanmetto a long and thorough trial in a case of chronic cystitis, accompanied with stricture, the result of which warrants me in saying Sanmetto is unsurpassed by any other preparation with which I am acquainted. Its effects are prompt and positive.

RACHAEL J. KEMBALL, M. D., Buffalo, N. Y.

FREQUENT AND SCALDING MICTURITION-Renol afforded complete relief within twenty-four hours in the case of a lady suffering from excessive micturition with great scalding. My experience with Renol in this case confirmed the opinion I had formed of Renol from its formula, that physicians can prescribe this remedy with entire confidence in disorders of the kidneys and bladder.

WOODSTOCK, KY.

W. H. BENTLEY, M. D.

I CAN say that Peacock's Bromides will do all that is claimed for it, it is much more active and certain than the commercial salts.

G. H. CHAPPELL, M. D., Grand Rapids, Mich.

LABOR SAVING: The American Medical Publishers' Association is prepared to furnish carefully revised lists, set by the Mergenthaler Linotype Machine, and printed upon either plain or adhesive paper, for use in addressing wrappers, envelopes, postal cards, etc., as follows:

List No. I contains the name and address of all reputable advertisers in the United States who use medical and pharmaceutical publications, including many new customers just entering the field. Price, $1.25 per dozen sheets.

List No. 2 contains the address of all publications devoted to Medicine, Surgery, Pharmacy, Microscopy, and allied sciences, throughout the United States and Canada, revised and corrected to date. Price, $1.25 per dozen sheets.

The above lists are furnished gummed, in strip form, for use on the "Plymouth Rock" mailer, and will be found a great convenience in sending out advertising matter, sample copies, and your exchanges. If you do not use a mailing machine, these lists can readily be cut apart and applied as quickly as postage stamps, insuring accuracy in delivery and saving your office help valuable time.

Send for copy of By-laws and Monthly Bulletin. These lists will be furnished free of charge to members of the Association. See "Association Notes" in The Medical Herald. CHARLES WOOD FASSETT, Secretary, corner Sixth and Charles streets St. Joseph, Missouri.

Certainly it is excellent discipline for an author to feel that he must say all he has to say in the fewest possible words, or his reader is sure to skip them; and in the plainest possible words, or his reader will certainly misunderstand them. Generally, also, a downright fact may be told in a plain way; and we want downright facts at present more than any thing else.-RUSKIN.

Original Articles.

CONCERNING A GENERATION OF KENTUCKY PHYSICIANS.*

BY LYMAN BEECHER TODD, M. D.

It is esteemed a pleasure and an honor to greet you, my Fellows, upon this the fortieth anniversary of our beloved Society, of whose history we may justly be proud, and of whose present and future usefulness we confidently feel assured.

Nor is this place of meeting unworthy of this occasion-Harrodsburg, whose honored guests we are, time-honored, historic old town of Harrodsburg, whose official seal bears a hero's name. The Kentucky State Medical Society, now within her hospitable gates, gladly claims the privilege of doing homage to the name and memory of Jaines Harrod, brave and knightly Harrod, and to his chivalrous co-patriot pioneers-men and women-noble fathers and noble mothers, they were of a noble race; and with sacred reverence we now think and speak of those mothers whose hands molded the bullets for the trusty Kentucky rifles with which their heroic husbands, fathers, and brothers defended their homes and firesides from the torch, tomahawk, and scalping-knife of the lurking and bloodthirsty savage. The narrative of self-sacrifice, hardships, heroism, and achievements of the grand and noble men and women, whose impress is stamped upon the Christian civilization of our day, as recorded by the faithful historian of those early and stirring. times, proudly challenges comparison with aught in classic history that Roman ardor ever knew or Spartan valor ever dared.

*An address delivered before the Kentucky State Medical Society at Harrodsburg, Ky., June 13, 1895.