was of the size of half a walnut, with a prolongation on one side, which reached the neck of the bladder and penetrated the prostatic urethra.Annales des Maladies des Organes Génito-urinaires, Paris; Edinburgh Medical Journal.

ANARCOTINE.-Dr. William Roberts, in the British Medical Journal, calls attention to this alkaloid of opium, which he believes has been neglected. This drug, which is generally known as narcotine, having been so named by its discoverer, Derosne, has been renamed by Palmer because it has been shown to be quite devoid of narcotic properties. Smyrna opium contains one fourth as much of this alkaloid (2 per cent) as it does of morphine (8 per cent), while in Bengal opium, which is popularly used in India, it is present in larger quantity (morphine 4, against narcotine 6 per cent). This drug came into notice in India about fifty years ago, when quinine was very scarce and expensive. The important investigations of Palmer show incontestably that it is scarcely inferior, and in some classes of cases is superior, to quinine as an antiperiodic. From the observations of nearly one thousand cases he concludes that in 70 per cent the fever was arrested at the second paroxysm after the medicine was administered; in 20 per cent the arrest was equally sure, but not so quick; and in 10 per cent it did not appear to have any curative effect. When there is an intolerance of quinine it was decidedly more efficacious. Garden, a few years later, believed that it was next in value as an antiperiodic to quinine. The doses range from one to three grains, and it is perfectly insoluble and tasteless. The chloride is very soluble and of an intensely bitter taste.-American Journal of Medical Sciences.

A CASE OF SEXTUPLETS. -Vassali (British Gynecological Journal, August, 1895,) has recorded the birth of six children at one birth. The patient, who was thirty-six years old, grew anemic and weak in the early months of her pregnancy, and complained of chilly feelings. She did not feel motion. In the fourth month the abdomen was as large as that of a normal pregnancy at term, and the woman daily expected confinement. On the one hundred and fifteenth day of gestation the membranes ruptured while straining at stool, and a foot prolapsed. Before this she had experienced no pain. A fetus was delivered. The next morning pains. began, with chills, flowing, rise of temperature, and vomiting, and it was decided to terminate her pregnancy. The membranes were ruptured, a foot brought down, and a second fetus was delivered. A third bag of membranes presented, and a third fetus delivered, and so on till the fifth, The process lasted two hours, when an endeavor was made to hasten what was thought to be the third stage of labor, but the attempt to remove the placenta revealed a sixth amniotic sac and fetus. All the fetuses were born alive and moved vigorously. The sexual organs were differentiated, four being males and two females. The large single placenta bearing the

six amniotic sacs was unfortunately so lacetated that further investigation was useless. The specimen is preserved in the museum of the Obstetrical School at Milan.

OPERATION FOR PERFORATED GASTRIC ULcer; RecoveRY.-Dr. Kirkpatrick (Montreal) reports the case of a woman, aged twenty-four, chlorotic, and suffering from severe gastric pain for two years. Two days before admission to hospital she had severe epigastric pain, and vomited "darkcolored" matter. On admission, temperature was 104.5°, pulse 120, respiration 44. There was tenderness, but no marked abdominal distension. The following day the abdomen was opened, the anterior stomach wall was found adherent to the parietes to a slight extent, and in breaking the adhesions the perforated ulcer was discovered in the anterior wall, a little to the right of the esophageal line. No stomach contents escaped. The aperture was closed carefully, a rubber tube inserted into the right flank, and the abdomen closed. The tube was taken away after twenty hours; on the third day small quantities of milk were given by the mouth. The wound healed by first intention, and a good recovery was made.-Montreal Medical Journal.

CATHETERIZATION OF THE URETERS.-Nitze regards the difficulty experienced in this procedure as being due to the fact that the sound commonly used with the cystoscope forms an angle with the ureter as it traverses the bladder wall. He has therefore adapted to the cystoscope a metallic sound of variable curve, of which the beak is covered by that of the cystoscope. When the latter reaches the bladder this hollow sound is directed toward the side of the opening of the ureter, and a flexible sound passed along it readily enters the orifice.—Centralblatt f. Chirurgie; Edinburgh Medical Journal.

GRAMMAR CLASS.-Teacher: Compare liar.

Student: Positive, prevaricator; comparative, liar; superlative, writer of medical testimonials.-Transactions Antiseptic Club.

Special Notices.

A prominent physician writes as follows:

MESSRS. MCKESSON & ROBBINS, I have three cases in which I have been experimenting with Tartarlithine, and the same in combination with Sulphur. I am surprised to find what appears to be the pronounced value of the sulphur combination. All of the cases present arthritic symptoms, and have been markedly benefited by the tartarlithine treatment after the failure of other treatment extending over long periods. One case, a man who had for eighteen months suffered from a lumbago which nearly disabled him, is now so much improved, after using 100 tablets of tartarlithine with sulphur, that he considers himself well. Certainly his disorder is under thorough control.

I saw somewhere in a medical journal a rather romantic description of a preparation which had become very popular in England under the name of the Chelsea Pensioner. It was a secret preparation for a time, but achieved such notoriety for its value in the treatment of gouty joint affections that some charitably disposed person paid a large sum for the formula and then made it public for the benefit of suffering humanity. The preparation was composed of cream of tartar, sulphur, and powdered ginger. If the efficacy of Chelsea Pensioner was as stated, then the combination of tartarlithine and sulphur should be much more potent in the same lines. The foregoing may be quite familiar to you, but I send it in any event, and regret that I did not make a note of the journal in which the account appeared. I shall be glad if you will send me another supply of both the tartarlithine and its sulphur combination, as I have used all I had and desire to continue my experimental treatment of the cases to which I have alluded.

EXTREME PAIN OVER BOTH KIDNEYS.-My son-in-law suffered extreme pain over both kidneys and a scanty secretion of urine. He took eight Renol tablets, one every four hours, and was greatly relieved. I am very favorably impressed with Renol and will certainly prescribe it. W. S. O'NEAL, M. D.

LANCASTER, Ky.

IN reporting the case of a woman suffering from neoplasm in the stomach, Dr. Ernesto Costa, of Alagna, Italy, says:

"One can easily imagine the intense pain which entirely prevented her sleeping. I tried chloral and sulphonal, and although the latter answered fairly well for a time, it soon became necessary to discontinue it. I then administered Bromidia with the following results:

"I. It produced refreshing sleep.

2. It soothed the pain, and thus rendered alimentation possible.

"3. Although given in frequent, and sometimes in tablespoonful, doses, it never produced any nervous or cardiac disturbance."

PERMANENT AND RELIABLE.--A letter from Dr. Policarpo Diaz, of Guanaxuato, Mexico, to Scott & Brown says that, in 1889, he purchased twenty bottles of Scott's Emulsion. At that time he was "suffering from a terrible attack of tuberculosis." He says he does not now have the slightest symptom of that disease, and is in the best of health. He adds that, at the time of writing, April, 1895, he has one of these twenty bottles on hand; and "although enough time has certainly elapsed for the Emulsion to separate, yet it is in perfect and unchanged condition."

PRE-SENILITY-OVARIAN PAINS; CHRONIC ENDOMETRITIS.; I have been using Sanmetto for the past two years with surprisingly good success. As a remedy for declining virility there is no equal, in fact it is a sine qua non. Have also given it with

success in ovarian pains, and in that troublesome and painful condition due to chronic endometritis. Sanmetto is an important addition to our therapeutical means. Its beneficial effects are simply marvelous. J. D. BENNETT, M. D., Crystal River, Fla.

INCIPIENT DIABETES.-Renol has given me good results in a case of Incipient Diabetes. In a case of retention of urine with the presence of a large amount of uric acid, the patient was given Renol tablets and was all right in a few days.

D. MCCURDY, M. D., 1072 Lorain St., Cleveland, O.

My success with Peacock's Chionia has been more than I expected; the patient, a lady, received more help from it than she had from all the medicine she had taken from different doctors in five or six years. I have placed great faith in Peacock's Chionia and I can not speak in too high terms of its efficacy.

DES MOINES, IA.

S. J. WESTON, M. D.

ULCERATION OF THE BLADDER.-I have just treated the worst case of ulceration of the bladder that I have seen for fifty years with Renol sodii lithia comp. with absolute success. My patient is perfectly well. I found Renol a perfect god-send in this case, and would recommend it to every doctor.

A. PIERONNET, M. D., Cape Girardeau, Mo.

I HAVE used Cactina Pillets for several years past, with the most satisfactory results, in such cases wherein they are indicated.

ST. LOUIS.

A. H. OHMANN-DUMESNIL, A. M., M. D.

STARVATION.—If your patient is suffering from impaired digestion, or, in other words, starving, not from lack of food, but from lack of digestion, then prescribe Seng, two teaspoonfuls before each meal.

INTERSTITIAL Nephritis, Urethritis, and CYSTITIS.-During a practice of fortythree years I have never seen any thing equal to Renol in the treatment of Cystitis, Urethritis, and Interstitial Nephritis. It has worked wonders with my patients.

DAVID E. SMITH, M. D., Rooms 140 & 141 Times Building, New York, N. Y.

LABOR SAVING: The American Medical Publishers' Association is prepared to furnish carefully revised lists, set by the Mergenthaler Linotype Machine, and printed upon either plain or adhesive paper, for use in addressing wrappers, envelopes, postal cards, etc., as follows:

List No. I contains the name and address of all reputable advertisers in the United States who use medical and pharmaceutical publications, including many new customers just entering the field. Price, $1.25 per dozen sheets.

List No. 2 contains the address of all publications devoted to Medicine, Surgery, Pharmacy, Microscopy, and allied sciences, throughout the United States and Canada, revised and corrected to date. Price, $1.25 per dozen sheets.

The above lists are furnished gummed, in strip form, for use on the "Plymouth Rock" mailer, and will be found a great convenience in sending out advertising matter, sample copies, and your exchanges. If you do not use a mailing machine, these lists can readily be cut apart and applied as quickly as postage stamps, insuring accuracy in delivery and saving your office help valuable time.

Send for copy of By-laws and Monthly Bulletin. These lists will be furnished free of charge to members of the Association. See "Association Notes" in The Medical Herald. CHARLES WOOD FASSETT, Secretary, corner Sixth and Charles streets St. Joseph, Missouri.