From time to time re-examine the blood and observe the rapid and progressive increase in the red cells coincidently with an obvious improvement in the child's color and appearance. One such case will convince you that PEPTO-MANGAN ("GUDE") is a true "BLOOD-BUILDER." Samples and literature upon application to LABORATORY, M. J. BREITENBACH COMPANY, LEIPZIG, GERMANY. Agents for American Continent, 100 WARREN ST., (TARRANT BLDG.) VIII MARCHAND'S EYE BALSAM (C. P. Vegetable Glycerine combined with Ozone.) THE MOST POWERFUL AND AT THE SAME TIME HARMLESS Cures Quickly all Suppurative and Inflammatory Diseases of the Eye: Catarrhal Conjunctivitis or Ophthalmia, Purulent Conjunctivitis, Ophthalmia in Children, Inflamed and Granular Eye Lids, Etc. Send for free 300-page book "Rational Treatment of Diseases caused by Germs," containing reprints of 140 scientific articles by leading contributors to medical literature. Physicians remitting 50 cents will receive one complimentary sample of each, "Hydrozone" and "Eye Balsam." Marchand's Eye Balsam is put up only in one size bottle. Package sealed with my signature. Hydrozone is put up only in extra small, small, medium ari large size bottles bearing a red label, white letters, gold and blue border with my signature. Glycozone is put up only in 4-oz., 8-oz. and 16-oz. bottles bearing a yellow label, white and black letters red and blue border with my sig nature. DISTRIBUTING AGENTS: Thomas Christy & Co., 25 Lime St., London, England. John W. Lehman. 428 Camp St.. New Orleans, La. PREPARED ONLY BY Charles Marchand Chemist and Graduate of the Ecole Centrale des Sold by leading Druggists Avoid Imitations Mention this Publication. 57-59 Prince St., New York. "The best antiseptic is undoubtedly that which is the least harmful to man in LISTERINE a safe, trustworthy, non-toxic antiseptic, answering every An interesting little brochure, entitled: "The TREATMENT of DISEASES of the RESPIRATORY SYSTEM," LAMBERT'S LITHIATED HYDRANGEA A remedy of acknowledged value in the treatment of all dis- LAMBERT PHARMACAL CO., ST. LOUIS IX FOR SANMETTO GENITO-URINARY DISEASES. A Scientific Blending of True Santal and Saw Palmetto in a Pleasant Aromatic Vehicle. A Vitalizing Tonic to the Reproductive System. SPECIALLY VALUABI É IN PROSTATIC TROUBLES OF OLD MEN-IRRITABLE BLADDERCYSTITIS-URETHRITIS-PRE-SENILITY. PAPINE IS THE PAIN RELIEVING PRINCIPLE OF OPIUM. ONE CAN DISPENSE WITH OPIUM THE NARCOTIC; ONE CANNOT DISPENSE WITH OPIUM OPIUM THE PAIN-RELIEVER. PAPINE PRODUCES NO TISSUE CHANGES, NO CEREBRAL EXCITEMENT, NO INTERFERENCE WITH DIGESTION. Sample (12 oz.) Bottle Ecthol Sent Free on Receipt of 25 Cts. to Prepay Express. FORMULA:--One fluid drachm is equal in anodyne power to 1-8 gr. Morphine. BROMIDIA IODIA BATTLE & CO., CORPORATION, ST. LOUIS, MO., U. S. A. Literary and Publishers' Department. THE OFFICIAL GUIDE.-Among the many monthly periodical publications of this country, most of which are devoted to articles of a literary character, it is interesting to note one that is primarily devoted to the dissemination of public information. We refer to "The Official Guide of the Railway and Steam Navigation Lines of the United States, Canada, Mexico, Cuba and Porto Rico," so large a portion of the contents of which consists of information as to the most recent railway and steamboat schedules, which embraces the latest news as to all changes in such schedules. Those of us who have suffered the inconvenience of missing a train for the want of this latest information (and who has not done so at some time?) will not need to have its importance impressed upon us. The latest information as to such changes appears in each monthly issue of "The Officail Guide," and the extent to which this important news affects people generally may be realized from the following extract from the leading editorial in its December issue: "We publish in our December issue not merely the current figures for all railway lines, but also information conveyed to us by mail and by telegraph respecting changes on 619 time-tables, affecting not less than 15,846 trains and giving the latest current news as to the time of the arrival and departure of trains at not less than 28,000 stations. The number of people who are affected by these changes may be counted by millions. While the extent of this news printed in the December 'Guide' is greater than usual, nevertheless the smallest number of new time-tables respecting which current information was published in 'The Guide' for any month in 1901 was 226." A REMEDY PROPOSED FOR THE EVIL OF SUBSTITUTION— By J. D. Williams, M. D., New York.-There can be no subject of more importance to physicians than the violation of their confidence on the part of a dishonest dispensing druggist. Law will not make a dishonest man honest, but the right law properly executed will prevent a criminal's further infliction of injury upon society. The requirement of a license to all druggists who dispense drugs or medicines, revokable upon the licensee's being convicted of substituting any ingredient drug or medicine other than, and in lieu or instead of, that specified in the prescription, order or request in writing, of any physician, would go a long way to aid in the matter of honestly filling prescriptions. Let the medical societies induce their respective State legislatures to enact a law requiring such a license, with a simple and practical procedure for establishing the guilt and enforcing the penalty against infraction, and the practice of substitution would soon cease. Let proceedings for revocation of license be before the court, board, or officer, empowered to issue the license, and be set in motion at the relation of either the Board of Health, a local medical society, or the purchaser upon whom the fraud and imposition had been done, or of the physician by whom the prescription or order was issued or given, or of any person, firm or corporation for whose brand or make of drug or medicine the |