February; the same magazine treats of Russia's internal troubles, which led up to the massacre of citizens by soldiers in the streets of St. Petersburg on January 22. There is also an article by Prof. Amos S. Hershey, entitled "What Justifies Intervention in War?" and a brief sketch of the career of General Stoessel, the Russian defender of Port Arthur.

If you contemplate a trip to San Francisco, the pleasure seeker's great city, the Hotel Del Monte, nestling in scenes of beauty, or Southern California with its lovely seaside resorts, orange groves, beautiful gardens, and quaint old missions, the only way to reach these magical scenes without suffering any of the inconveniences of winter travel is over the Union Pacific and Southern Pacific fast trains. Smooth roadbed. Superb equipment. Inquire of H. G. Kaill, A. G. P. A., 901 Walnut street, Kansas City, Mo.

Yellow journalism has given Dr. William Osler an unenviable notoriety by purposely printing misleading statements from late addresses. Dr. Osler's unpopular remarks are here correctly quoted: "My second fixed idea is the uselessness of men above sixty years of age, and the incalculable benefit it would be in commercial, political and in professional life if, as a matter of course, men stopped work at this age." The daily papers throughout the land make Dr. Osler put his age limit at 40, and treat as a serious statement his jovial recommendation to a youthful audience in Canada that the Canadian governmen impose an export duty on its girls.

Dr. Joseph MacDonald, Jr., who for many years has been connected with the International Journal of Surgery as manager and managing editor, has severed his connection with that journal and has purchased the American Journal of Surgery and Gynecology, formerly owned and published by Dr. Emory Lanphear of St. Louis. Dr. MacDonald will publish the latter journal in New York under the name of the American

Journal of Surgery. Several of the most prominent surgeons in New York will be contributors to it. In view of Dr. MacDonald's long and successful career as a medical editor, we predict a prosperous life for this new journal under such an efficient gentleman.

This institution graduated its first class, consisting of two students, in 1870. It has been in continuous and successful operation since that time, graduating classes every year. The number steadily increased until a few years ago, when the general high-water mark in attendance of medical colleges in America was reached. With the longer and mcre difficult courses and the tendency to over-crowding in the professions, the classes have diminished again. As the quality was never so good, this result is regarded as satisfactory to the profession at large.

The commencement exercises will be held in the Central High School Anditorium on the evening of April 11th, at 8 p. m.

The graduating class numbers thirtyfive men.

The semi-annual meeting of the Alumni Association will convene at the college building at 2 p. m. of commencement day.. A literary and clinical program will be presented and regular business transacted. Clinics will be held for the special benefit of members and guests at St. Joseph's hospital at 9:30

a. m.

After the commencement exercises a banquet will be held at the Coates house for the alumni, graduates and faculty.

ON TO PORTLAND.

The Bourlington Route has been named by the Missouri Valley Medical Association as the official line to the next meeting of the American Medical Association at Portland, Ore., in July.

The trip planned is by way of Lincoln, Neb., and Butte, Mont., with stop-over at Livingston to visit the Yellow Stone Park. Thence through Butte, Mont., Spokane, Wash., and Tacoma, Wash.,

with free side trip to Seattle, Wash., thence to Portland, Ore.

The Burlington has a fast train over this route leaving Kansas City daily at 6:10 p. m., Leavenworth at 6:42 p. m., Atchison at 7:15 p. m., St. Joseph at 8:25 p. m., Omaha at 11:10 p. m., and Lincoln at 12:55 a. m., reaching Yellow Stone Park at noon the second day. A very low round trip of $45.00 will be made for this meeting. Tickets being

on sale June 27th, 28th, 29th and 30th, and July 1st, 2nd, 3rd, 6th, 7th and 8th, bearing final return limit of 90 days.

A variety of return routes is offered. For instance, return is allowed the same way or through Salt Lake City, Ogden and Colorado. For $7.50 higher passengers may return, Northern Pacific, Great Northern or Canadian Pacific, through St. Paul, thence back through Omaha to Kansas City, this arbitrary amount being less to Omaha and St. Joseph; for $11.00 additional, passengers may return through San Francisco and Los Angeles. They can then come back through Salt Lake City and Denver, or by way of the Santa Fe, or the Southern Pacific through Texas. From Portland there will be a number of side trips around Puget Sound and up to Alaska. You had better make your arrangements right away. For full particulars address the MEDICAL INDEXLANCET.

THERAPEUTIC AND MEDICAL NOTES.

THE ZERODONE.

Demonstration of the Zerodone by Dr. John F. Beurman, who gave a full description of the construction of the apparatus. By request of Dr. Beureman, Dr. Achilles Rose spoke on his experience with dry cold or hot application by means of contrivances constructed on principles on which the Zerodone is a great improvement.

Twenty years ago I happened to consult a book on genito-urinary diseases, by Furbringer, which I considered the

mbest treatise on the subject at that time. The therapy of acute prostatitis as recommended by Furbringer, consisted in absolute rest, application of leeches, warm fomentations, Sitz baths, regulation of the bowels, under certain circumstances narcotics, and as a last resort operation. Not a word was said of the most rational and the most reliable remedy in this affection; the cooling apparatus was not mentioned. At that time I had already had experience with the method of applying dry cold to the inflamed prostata by means of a contrivanve constructed on the principle of Arzberger's instrument. I used Mattison's rect cone. I wrote to Furbringer, and had the satisfaction to receive his letter of approval. Rectal cones connected with a contrivance as convenient and simple as the Zerodone, are of great benefit in case of acute or chronic prostatitis; in acute, by relieving pain and reducing inflammation; here the lower temperatures of the water running through the cone are indicated; in chronic, by aiding absorption and stimu lating circulation; here warm water is required, instead of cold as in acute prostattis.

THE USE OF GLYCOZONE IN GYNECOLOGY.

BY C, H, POWELL, A. M., M. D.,

It is surprising how physicians fall into habits regarding the use of certain agents in their practice, and how loth they are to resort to something new. No doubt this fact exemplifies the maxim: "Be not the first by whom the new is tried, nor yet the last to lay the old aside." This saying, were it put into active practice, would interdict the use of any new drug or remedy, as from the very nature of things a leader must be acknowledged, and that leader would himself violatae the above maxim. In the treatment of uterine and ovarian diseases the well-known glycerole of tannin tampon, or the use of glycerine and Goulard's solution, or glycerine with other astringents, has been for years recognized and appreciated by gynecolo

TO PHYSICIANS, SURGEONS and

DENTISTS:

ANTIGERMOL, ROBINSON'S Antiseptic, Germicide, Prophylactic and Disinfectant.

Antigermol represents the active constituents of the following drugs, all of which from long usage by the medical profession have become popular as Antiseptics:

Eucalyptus, Wintergreen, Thyme, Wild Indigo and Peppermint, in combination with chemically pure Bo racic and Benzoic Acids.

Dose-Internally-A teaspoonful to a dessert spoonful in a little water, 3 or 4 times daily. ExternallyIt may be used pure or diluted with warm or cold water as the case may indicate.

Antigermol as an internal remedy is efficient in disorders of the digestive tract, particularly where there is fermentation present, also in Dysentery, Diarrhoea, Typhoid and other fevers.

As a local application it is invaluable to the Surgeon as a prophylacLic Wash preceding an operation, una as an injection and wash in Abscesses, Uulcers, etc. ParticularI 18 Antigermol adapted to the use of the Dentist, in whose practice there is such a wide application for so pleasant an Antiseptic and Deoderant.

IN PINTS, PER BOTTLE, 75c.
Please specify ROBINSON'S.

tions.

This valuable remedy is the result of much careful study, and is a scientif combination of the following ingredients:

Phosphoric Acid, Tinet. Hydrastis, Albuminate of Iron, and Calisaya Bark, in a vehicle composed of Glycerine, Sherry Wine and Aromatics.

No physician can fail to recognize in this combination the Ideal Tonic and Reconstructive. Each ingredient is the type of its class. Phosphoric Acid -Tissue builder and Nerve restorer. HydrastisTonic to Mucuous Membranes. Albuminate of Iron -Regenerator of Red Blood Cell. Calisaya-Antimalarial, Tonic and Febrifuge. Glycerine-Antiferment and Emolient. Sherry Wine-Stimulant and Tonic. The whole combined to form a delicate, appetizing cordial, which agrees with even the weakest and most delicate stomachs.

Calisaya, Phospho, Ferro-Albuminate, has proven itself of great value in the following cases:

In NEURASTHENIA, in DYSPEPSIA, in COUGHS promotes expectoration and furnishes food to the wasting tissue.

In convalescence from disease such as Malaria, Typhoid, Diphtheria, etc., all of which cause a depletion or diminution of the Red Blood Cell, this Tonic acts like a charm.

The Iron in an organic form is readily absorbed all Malarial Fevers, and other ingredients give tone and forms rich, red blood, the Calisaya eliminates and strength to the weakened system. producing in a short time a perfect state of vigorous health. 16 OZ. BOTTLE $1.00.

WE ALSO MAKE

FLEXNER'S

Pints $1.00

For sale by Druggists.

gists over the entire world. In the clinics solutions of these agents are ever at hand, and habitually are ensconced into. the vaginal canal with very little regard as to the scientific results that will accrue. It has often occurred to the writer that many of the solutions used by gynecologists favored the development of bacilli, and no doubt contributed in no small degree to the lighting up of attacks of pelvic peritonitis so frequently enountered by gynecologists. Glycerine no doubt is without a peer in successfully treating a long range of diseases that afflict women, as the wellknown hygroscopic qualities of the remedy bring about a local blood-letting from the hyperæmic structures which, when followed by hot douching, is usually relied upon to reduce many inflammatory complications of the uterus and its adnexa. Not being satisfied, for the reasons above given, with the usual formulæ of glycerine in gynecology, a sample bottle of glycozone which came to my desk several months ago, although not referred to in the treatment of diseases of women, appealed to me. Accordingly, in view of the highly oxygenated properties of the remedy, which I believed would necessarily possess bactericidal properties, I was induced to try glycozone in my gynecological practice; the results were so pronounecd, and the beneficial influence of the remedy so decided and permanent, that I have for several months past persistently resorted to glycozone in preference to anything else in my local work. I will outline the following clinical case as indicating its usefulness in the conditions stated, six others having been cured by the same treatment:

Case 1.

Subinvoution Uteri Consequent to Miscarriage.

Mrs. Ella McL., aged 28, suffered a miscarriage at the end of the fourth month, following a severe fall from her carriage. The bleeding was severe until the placenta was entirely removed, when it ceased. Ergot was used regularly to check a tendency to recurrent and con

tinuous hemorrhage which necessitated the employment of local treatment. Curettage was first employed, the uterus thoroughly washed out with carbolic solution, and then a cotton wool tampon of glycozone pure pushed up to the cervix uteri. The uterus at the time of the first application measured five and a half inches in depth, subinvolution of the organ being most marked. On the second day, the tampon was removed, and the uterus found to have become reduced in size at least one inch, its depth measuring four and a half inches, very much to my surprise. In the next twenty-four hours following the glycozone tampon there was but little evidence of further reduction-the depth remaining about the same. Twenty-four hours later, however, the uterus showed a decline in depth of a half inch, and this beneficial influence of the glycozone continued unremittingly thereafter until at the end of eight days the uterus measured but two and a half inches, and the cure of the patient was complete.

In 1894, Lantz treated two exopthalmic-goitre patients with milk from thyreoidectomized goats. The results were so favorable that the treatment was ap

plied to four other patients, all of whom as a consequence showed marked improvement and gain in weight.

In 1894 Drs. Ballet and Enriquez took the blood of thyreoidectomized dogs that hadf lived long enough to experience the blood changes which loss of thyreoid function is sure to entail-and injected that blood into patients suffering from exophthalmic goitre. The results were so enicouraging that other practitioners soon adopted the method, or a modification of it. The Deutsche Medicinische Wochenschrift, No. 38, 1899, contained a report of three cases of exopthalmic oitre, in the practice of Dr. Burghart, that improved under the treatment, two of them decidedly. Dr. Burghart did not confine himself to the use of injections, but administered a dried alcoholic extract of the blood.

Later, a Darmstadt chemical house