it is therefore Resolved, That all physicians having knowledge of the existence of cholera, measles, malarial fever, rubella, typhoid fever (enteric fever), whooping-cough, typhus fever (spotted fever), tuberculosis (in any of its manifestations), pneumonia, scarlet fever, erysipelas, smallpox, variola, or varioloid, puerperal fever, plague, chickenpox (varicella), trachoma, diphtheria, leprosy, diphtheric croup, tetanus, cerebrospinal meningitis, hydrophobia, anthrax, shall forward the same to this board on cards prepared for the purpose at the earliest moment after the establishment of the diagnosis; and be it further Resolved, That all practitioners of veterinary medicine having knowledge of the existence of glanders (farcy), anthrax, tuberculosis, tetanus, or rabies in animals or in man, shall likewise report the same, etc.-Amer. Med. Anti-typhoid Inoculation has, according to a recent report, been introduced into the German army. The troops proceeding to Southwest Africa have been made the subject of treatment.-Amer. Med. No More Deformed Feet in China.-The Dowager Empress of China is making some progress in her old age. One of her late commendable acts was the issuance of a decree against deforming the feet of women to make them small. That cruelty has long been a custom among the women of rank in China, and if it is abolished it will be highly creditable to the Empire.-Amer. Med. Chinese Medicines.-Though the pill habit is said by medical journals to cause more dyspepsia than it cures, it has at any rate the sanction of antiquity. In an article which Dr. H. L. Norris, a British naval surgeon on the China station, contributes to one of the medical journals he remarks that doses in the Chinese pharmacopeia are invariably large and the pills are "taken by the hundreds." The Chinese, he adds, possess an enormous veneration for antiquity, and beside powdered deers' horns to promote longevity, and tigers' bones to promote bravery, dose themselves with fossil ivory, fossil crabs and shells, ancient soot and water in which a few copper coins of an early dynasty have been boiled. Other imaginative remedies are scorpions, dried silkworms, baked toads, wasps' nests and cockroaches. At the end of a considerable catalogue of similar prophylactics Dr. Norris observes that, though his list is far from complete, it will show through what a varied range of thought Chinese ideas have moved in attempts to relieve the diseases common to humanity. Perhaps the most curious of all preventive medicines is a soup made from a black cat which is drunk by blacksmiths in Canton to prevent burns from hot metals. If the remedies are in themselves nauseating the nomenclature of the drugs is almost literary. "The arrow of the hundred medicines," "thunderpills," "water dragon bones," "the king of the field boundaries," "thousand tales, worth seed" are some of the names.-Am. Med. MATERIA MEDICA AND THERAPEUTICS. Under charge of EMIL WESCHCKE, Ph. G., M. D., Coal-Tar Products In Fever.-In an excellent and exhaustive article on "The Physiological Action and Morbid effects of Antipyrin and Other Coal-Tar Products in Fever," in The Monthly Cyclopædia of Practical Medicine, CHARLES E. DE M. SAJOUS, M. D., draws attention to the following observations: I. Antipyrin promptly causes marked vasoconstriction. II. The vasoconstriction, both of the arteries and veins, may be sufficiently marked to obstruct the circulation in, and cause engorgement of, the capillaries. III. Very large doses, small doses too, frequently repeated, or small doses in subjects whose adrenal system is abnormally sensitive, may cause sufficient vasoconstriction of the arteries and veins to greatly reduce. their calibre. The arterial blood in the capillaries is then exposed to the reducing action of the surrounding tissues sufficiently long to become transformed into venous blood, thus causing cyanosis. IV. When the adrenal system is unable, owing to congenital, acquired or temporal susceptibility, or an organic lesion of either of its component parts, to withstand the violent stimulation to which antipyrin subjects it, the functions of the adrenals may suddenly cease under the influence of even small doses of the drug, and the symptoms of adrenal failure appear. V. Antipyrin, in the stage of depression, reduces the temperature by causing adrenal insufficiency. The result ing dilatation of the great central vascular trunks causes depletion of the peripheral capillaries, and the internal temperature is thus raised, while that of the surface is lowered. VI. Antipyrin should not be used during toxemias, especially when fever is present. It only acts as an antipyretic by causing excessive hyperemia of the adrenals-a condition exposing the patient to general collapse, even when small doses are administered. Consideration of the above leads the editor back to the time when he prescribed his first dose of antipyrin, being luckily at the bedside. It was a case of lumbago in an otherwise healthy young female. The urine being highcolored and the lumbar paint increasing and severe and pelvic congestion probably general, hot fomentations of pilocarpus with digitalis leaves were ordered as a cushion to lie upon. The pain continuing I administered .5 gr. antipyrin, dissolved in water. It may have been about five minutes when the patient began to cry in fright, calling that she was getting blind. All at once the face assumed a dusky, cyanosed hue, the eyes became expression less, nostrils dilated, and the lips swollen to three times their size. I felt the pulse fast and weak, the upper breast, neck and arms were discolored as if by measles, the patient trembled, and then suddenly after a hurried stimulant of whiskey and external mustard over the heart, and heat to feet with massage, broke into a profuse sweat, began to vomit and involuntarily passed urine and fæces. After an hour's rest, she felt strong and reported all pain completely gone. Nature had through explosive violence thrown off the shackles of both drug and disease. Antipyretic Medication. - SOLOMON SOLOS-COHN, M. D., speaks of the danger of unskillful antipyretic medication, with the incidental conclusion: "Indeed, many persons die of pneumonia because their hearts have been weakened by coal-tar products given in previous illnesses or self-administered for headache." Often after the subsidence of acute gonorrheal symptoms a subacute cystitis with intense burning of the urethral inflammatory spots occurs, especially when the urine is concentrated, In such cases the liquid extracts or tinctures, being strongly alcoholic, are not of direct or soothing service. I have found the following better: B Rhizoma tritici, Seminis lini, Fol. buchu, Fol. uvæ ursi aa. partesæquale, s. t. s. 3ss to 8 oz. boiling water, strain and drink ad libitum. Formaldehyde and Urotropin.-Since the former is employed to preserve specimens of urine, we must remember that it gives a test similar to that of present albumen and also to interfere somewhat with the character of the precipitate when the latter is present. During administration of urotropin, which liberates the formaldehyde to act as a renal and vesical antiseptic, this fact should be borne in mind. GENITO-URINARY DISEASES. Under charge of LOUIS GROSS, M.D., Clinical Lecturer on Genito-Urinary Diseases, College of Physicians and Surgeons of San Francisco. Gonorrhea. Abortive Treatment of Acute (Munchener Med. Woch., July 12, 1904.)-BETTMANN calls attention to the advantages which would attend such a plan of treatment, although the results thus far obtained have led most practitioners to regard any procedures of this kind with suspicion. As it is acknowledged that the gonococci penetrate the deeper epithelial layers very quickly, the author has endeavored to find a remedy which in addition to its bactericidal power would also bring about increased transudation and cause the cocci to come to the surface. He has had excellent results with a solution of protargol, in glycerin and water, in the following proportions: 10 gms. of protargol are dissolved in 45 c. c. of cold water, without shaking the vessel, and then enough glycerin added to make up 100 c. c. The best effects were obtained by applying the solution to the interior of the urethra with a specially devised hair brush. This is done daily, or every second day, until from six to eight applications have been made. In 42 cases treated, positive results were found in 20, 15 were negative, and 7 doubtful. The best results were obtained in those instances in which the treatment was begun three days or less after infection had taken place. The procedure is attended with very little discomfort on the part of the patient. A mucopurulent secretion may be present for several days, but after that the gonococci disappeared. Even in those cases which he considers negative because the secretion containing the cocci persisted there were no complications, not even a posterior urethritis. Acute Necrosis of the Lining Membrane of the Bladder. — DEAN reports (Practitioner, June, 1904) a remarkable case not only on account of the rarity of such a pathological condition, but also because the necrosed membrane was removed and the patient is now in good health. In boyhood, his water used to stop, and he passed urine frequently during the night. Present illness was ushered in with complete retention. Catheter could only be passed two inches, and calculus was diagnosed. The urethra was opened and a phosphatic calculus was removed. Later the temperature began to rise and as the urine dropped to three ounces in 24 hours, and, on opening the bladder suprapubically, the cast was removed. The pathological report showed it to be a portion of the membrane from the bladder consisting of necrosed vesical mucosa, submucosa and musculature. Almost the entire thickness of the bladder had sloughed away. The writer thinks that the necrotic action began prior to the removal of the calculus, and that the bacillus coli was the "foci et arigo" of the condition. Functional Diagnosis of the Kidneys.—(Weiner Klin. Woch., No. 28.)-KAPSAMMER places little value on cryoscopy of the urine, except that of a hint that something may be wrong when the freezing point is much below normal. He cites many cases which prove how fallacious it may be. In one case there was bilateral, gonorrheal pyelitis and stones in the right kidney, yet the freezing point of the blood was 0.56 (normal). He finds the Voelcker-Joseph indigo-carmine test valuable, firstly, to reveal the ureteral mouths; secondly, for the study of the type of the secretion; and, thirdly, with catheterization it is a valuable diagnostic measure much superior to the methylene blue test. He has modified the phloridzin test and has applied it in 70 cases. He makes a subcutaneous injection of .01 gm. phloridzin in an aqueous solution, just boiled, so that it is still warm. Sugar appears after 12 to 15 minutes in normal subjects. If it does not appear until |