Saline Laxative (Abbott) is obtainable in air-tight tin containers, also in bottles, and comes in three sizes: small, medium and large, so that any desired amount may be prescribed with the assurance that it will reach the patient in first-class condition. ESSENTIAL FACTS ABOUT DR. R. B. WAITE'S Antiseptic Local Anaesthetic 1st. IT IS ABSOLUTELY PURE. Each and every ingredient that enters into its composition must meet the requirements of our chemist, being subjected to a rigid chem. ical test before it is accepted from the man. ufacturer. 2nd. IT IS UNIFORM. Owing to the great care and scientific methods employed in combining the ingredients, it does not vary and you get the same results to-day, to-mor row or a year hence. 3d. IT IS SAFE AND RELIABLE. No impurities are being injected when using Dr. R. B. Waite's 'Antiseptic Local Anæs thetic. Our guarantee of absolute PURITY is your protection. 4th. IT WILL NOT DETERIORATE, but will keep for years, consequently you always have ready to your hand not only a perfect Anæsthetic, but Antiseptic as well. Dr. I. N. Cohen, of LaCrosse, Wis., under date of March 19, 1908, writes: "Last December a patient presented herself to me for examination of a wound on the right side of her face. I found that she was suffering from Carcinoma which had been operated on some two years previously. As the patient was 72 years of age and feeble, I doubted very much if she were able to stand chloroform, consequently decided to use your Anæsthetic. The operation lasted one hour and twenty minutes, during which time the patient cracked a joke once in a while, and claimed that she felt no pain whatever. The cancer was completely removed, and the best of it all is, it has not reappeared. I shall never feel that my dispensary is complete without your preparation." We want you to know our Anaesthetic as we know it, to be convinced of its unquestionable value in surgical operations, consequently we will send you for trial ONE DOLLAR BOTTLE FREE upon receipt of 25 cents to pay for packing and postage. PRICE-1 oz., $1.00; 6 ozs., $5.00; 12 ozs., $10.00; 20 ozs., $15.00. The Antidolar Mfg. Co. 68 Main St., Springville, N. Y. BRANCH: 498 Argyle Ave., Montreal, Quebec. SALICYLATES AS ANTIPYRETICS. "In the Calcutta Medical Journal for February, 1908, Ghosh makes a few observations on the salicylates as antipyretics and hepatic stimulants. He asserts there are few drugs in the Pharmacopoeia which can excel sodium salicylate in its action on the liver. It stimulates the latter to increased activity, causing an increase in the flow of bile, which is rendered more watery, and is, at the same time. excreted under a higher pressure. In ordinary fever, with some hepatic derangement and congestion, it has invariably been used with the customary diaphoretic mixture, with good results. Moreover, the general discomfort and the indefinite sort of pain over the whole body, so often complained of by such patients, are, as a rule, relieved by this drug. "When using the drug in large doses, as in acute rheumatic fever, one should always use the salt prepared from the oil of gaultheria. This has the advantage of not being depressant, and gives better results. as it does not contain any of the impurities of the artificial preparations." -Therapeutic Gazette, July, 1908. Physicians should bear in mind that all the salicylic acid in Tongaline is made from natural sources, and it is on this account that the results are so uniformly beneficial. Furthermore. as an hepatic stimulant and for chronic constipation Tongaline can not be equalled. THE LOCAL TREATMENT OF CATARRHAL CONDITIONS AFFECTING THE UPPER AIR PASSAGES. By E. C. Roemele, M. D., Frankfort, Ky.-E. J., aged 24. Diagnosis: Chronic nasal, catarrh. Duration, three years. Patient complained of a feeling of fullness in the nares and increase of the secretions, the character being thick and greenish, which dropped posteriorly into the pharynx, causing paroxysms of "hawking," which were more marked in the morning just after arising. The voice had a peculiar nasal intonation; the sense of smell was abolished almost entirely, and hearing was impaired, due to the extension of the inflammation into the eustachian tubes. The patient also complained of a constant dull headache. I at once prescribed Glyco-Thymoline, Local Anesthesia for Less Than Two Cents. NO INJECTION OF A DRUG, HENCE NO SYSTEMIC EFFECT. Chloride of Ethyl application by a new method. By this method there is no waste of material, whereas by other methods over 90% is wasted. This does the work with one-tenth the material of other methods. This produces a fine spray, instead of a stream, and can be held close to the part to be affected. Anesthesia produced in 30 seconds or less, by reason of the vaporized spray and the guaranteed absolute purity of the Chloride of Ethyl. No leakage or other waste. No blocking. No fine capillaries to clog. The Gebauer Chemical Co. are the pioneer manufacturers of this drug and are, therefore, in a position not only to furnish an absolutely pure product, but also put up in a neat and durable container that will keep the liquid in a pure state indefinitely. The tube is made of metal, handsomely nickeled and can be refilled at a greatly reduced cost. All glass tubes are more or less dangerous, since sunlight has a tendency to deteriorate the liquid. Chloride of Ethyl is useful in all minor surgery and as a preliminary to hypodermic and antitoxin injections. Try it, Doctor, in opening boils, carbuncles and abscesses; in treating felons, fistulas and fissures; in amputating fingers and toes; in removing small tumors; and in all minor surgery, or wherever a brief harmless local anesthetic is desired. Mailed anywhere in the United States or Canada, prepaid, upon receipt of the price. 100 c. c. tube, $1.60; 40 grm. tube, $1.00. THE GEBAUER CHEMICAL CO. Sole Manufacturers, and had him use the K. & O. Nasal Douche every four hours, using the GlycoThymoline in 25% solution. I directed him to spray his throat with an atomizer, using undiluted Glyco-Thymoline every four hours, and also gave him one teaspoonful of Glyco-Thymoline four times a day, internally. This was done on account of the catarrhal condition of his stomach. After two weeks the hawking had ceased, his voice took on a more natural tone, and hearing and smelling senses were improved. He continued to improve, when, after fifteen weeks he was entirely cured. There has been no return during the past ten months. HAMAMELIS VIRGINICA, In an address, delivered April 26, 1905, before the Danbury Medical Society on "The Practical Value of Old Remedies," John V. Shoemaker, M. D.. LL. D., of the Medico-Chirurgical College, Philadelphia, Pa., spoke of Hamamelis in the following terms: "Hamamelis Virginica, an excellent old-time remedy, has a well-defined range of usefulness within which it is without a rival. Externally and internally, it is sedative and astringent. It is used as lotion and ointment in many diseases and injuries of the skin, in legulcer and varicose veins. It is serviceable in acute and chronic diarrhea, internal hemorrhages, bronchorrhea, epistaxis (nose-bleed), and varicose ulcers, etc." Another prominent author says: "The distilled extract of Hamamelis is a valuable application to sprains and bruises. Hamamelis is very useful in checking epistaxis, bleeding sockets after the extraction of teeth, bleeding hemorrhoids, and many other forms of hemorrhage. An ointment containing Hamamelis is of service in burns, eczema, erysipelas, sunburn, seborrhea, acne, etc. When given internally, this remedy exerts an astringent and sedative action. It is also highly valued in the treatment of acute and chronic diarrhea, dysentery, hemorrhage from internal organs, purpura hemorrhagica, varicose veins and ulcers." These statements from reputable men concerning the usefulness of Hamamelis are well borne out in general clinical experience, provided, always, that a uniform, acive product, such as is only found in Pond's Extract, be employe Bronze Bust to Dr. Byron Robinson. The students of Dr. Byron Robinson are erecting a bronze bust to him. The affair is in the hands of Dr. Benjamin Orndoff, 2277 Wilcox avenue, Chicago, Illinois. A Monthly Journal of Practical Medicine. VOL. XXXVI. ST. LOUIS, Mo., December, 1908. No. 12. FILARIAL DISEASES. BY WILLIAM F. THORNTON, M. D., Bluefields, Nicaragua, Central America. [Written for the MEDICAL BRIEF.] In tropical and sub-tropical countries there occurs a group of endemic diseases comprehended under the term Filarial Diseases. These diseases occur in the lymphatic system and are attributable to the presence of a parasite, Filaria bancrofti. Under this head hemato-chyluria, elephantiasis (Arabum), lymph scrotum, varicose glands, lymphatic varix, and other forms of lymph-angiectasis are included; in other words, with a series of diseases connected with inflammation or obstruction of some part of the lymphatic system. There are five species of filarial worms (Filaria bancrofti (nocturna), F. loa (diurna), F. perstans, F. demarquayi, F. ozzardi), the embryos of which, very much alike in size and appearance, appear in the peripheral human blood. According as to whether they can be found in the peripheral blood during the night or day, or at any time, they have received distinguishing names: Filaria sanguinis hominis nocturna, f. s. h. diurna and f. s. h. perstans. HISTORY. These parasites of man were for a long time known only in their larval state. In 1863, Demarquay, in Paris, discovered that the fluid from the hydrocele of a Havanese, emptied by puncture, contained microscopic round worms, the embryos of a nematode. Three years later Wücherer, in Bahia, observed them in the urine of twenty-eight cases of tropical chyluria, and in one case of hematuria. Salisbury also observed them in a case of chyluria, and gave them the name of Trichina cystica. The next discoveries in Calcutta, Guadeloupe and Port Natal related to chyluria patients; until in 1868 Lewis, without having had any knowledge of these discoveries, discovered the embryos in the blood of man, and also in the lymphatic secretions of persons afflicted with elephantiasis scroti, and in the blood of hematuric people. He also, in exceptional cases, found them in apparently healthy persons. He concluded that these were not accidental coincidences, but that the different diseases were related, and were dependent on the presence of this hematozoon, to which he gave the name of Filaria sanguinaris hominis. The adult female of this species was discovered in Queensland by Bancroft, and soon after Lewis found it in Calcutta; it was described by Cobbold as Filaria bancrofti. The male was first seen by Bourne in 1888. Sir Patrick Manson has advanced the hypothesis that the adult of Filaria sanguinis hominis diurna is the Filaria loa. The embryo resembles that of Filaria bancrofti, but appears in the blood during the day only. Filaria perstans, in its embryo form, was discovered by Sir Patrick Manson in 1891, in the blood of a West African negro suffering from sleeping sickness. Later he found it in the blood films from natives of the Congo and Old Calabar. In 1897 he examined the blood of Carib Indians sent by Dr. Ozzard from British Guiana, and found larval filariæ closely resembling those of F. perstans, together with other sharp-tailed larvæ slightly larger in size, but equally deprived of a sheath (the sheath being characteristic of f. s. h. nocturna and diurna). He provisionally gave to these filariæ the name F. ozzardi. In 1898, at the post-mortem examination of two Demarara Indians, Dr. Daniels found the adult forms, both male and female, of the blunttailed embryos (F. perstans), and soon after the adult forms of the sharp-tailed embryos. This showed that the differently shaped embryos belonged to two different specimens, one of which was undoubtedly a new species, and retained the name, F. ozzardi, suggested by Manson. Adult forms of the African blunt-tailed embryo were next found by Dr. O'Neil at the post-mortem of a Congolese patient who died from sleeping sickness, and Manson, after a comparison between these and the British Guiana specimens, came to the conclusion that they were identical. Filaria demarquayi was discovered by Sir Patrick Manson in 1895, in blood films from natives of St. Vincent, West Indies. Identical embryos have been seen by Manson, Galgey, Low and St. George Gray in the blood of natives of St. Lucia, and Low found them also in the blood of natives of Dominica and Trinidad. The adult female form of F. demarquayi was found by Dr. Galgey in the body of a native of St. Lucia, in whose blood the embryos had been found during life. The male has still to be found. GEOGRAPHICAL DISTRIBUTION. Filarial diseases only occur in tropical and sub-tropical countries, and it exists for the most part endemically along sea coasts and on the shores of large rivers. Within these regions there are small, narrowly circumscribed centers to which the disease is confined, while the whole vicinity, notwithstanding similar climatic conditions, the presence of the intermediate host of these parasites, and the presence of abundant chance of the further introduction of the specific parasite, are quite or almost entirely exempt. |