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The Sequelae of La Grippe. Among all of the various acute and exhausting illnesses that afflict mankind, there is none that so generally results in distinct prostration as epidemic influenza -or la grippe. Even the grippal infections which are uncomplicated or unaccompanied by serious organic changes are more than apt to leave the patient in a thoroughly devitalized condition after the acute febrile symptoms have subsided. It is for this reason that the treatment of la grippe convalescence is of special importance. The anemic, debilitated, depressed patient requires a systemic "booster" that will not only stimulate but revivify and reconstruct. It is distinctly wise, in such cases, to commence vigorous tonic treatment as early as possible, preferably by means of Pepto-Mangan (Gude), the hemic builder and general reconstituent. This standard hematinic increases the vital elements of the circulating blood and, by increasing the appetite and improving the absorptive and assimilative functions, quickly restores both hemic and general vitality.

Constipation.-A prominent physician, in addressing a graduating class in medicine, once said: "Gentlemen, you will find the secret of success in keeping your patients' bowels open."

Most cases of constipation begin with some intestinal disturbance, and we must seek a rational treatment, beginning at the very seat of the trouble, i. e., intestinal indigestion. In very many cases of ill health, associated with intestinal indigestion, the bile is found to be deficient in both quality and quantity. This is also truc of the pancreatic secretion. The normal stimulants to the intestines are found in the pancreatic juice and in the bile; hence it is to these that we

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Bile is one of the most important secretions of the body, and as Nature's antiseptic serves to free the intestinal tract of those bacteria which cause disease. Further than this, it is of great service in relieving constipation. The enzymes of the pancreas are well understood to be indicated wherever the tone of the intestinal mcuous membrane is such that it is unable to perform its normal functions, either in digesting or assimilating fats and starches.

These two needful secretions can best be replaced temporarily and their natural flow stimulated by means of Pancrobilin.

The War Revenue Tax.-On another page of this issue the Dios Chemical Company announce that the price of Neurosine, the Safe Soporific, will not be affected by the war revenue tax. All druggists will continue to supply Neurosine in 2 oz., 4 oz. and 8 oz. bottles at 25c, 50c and $1.00. The maintenance of these low prices in the face of a steadily advancing drug market is commendable. For the sake of economy, if for no other reason, every physician should acquaint himself with the usefulness of Neurosine, which has long been considered one of our most dependable hypnoticsedative-antispasmodic remedies.

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The principal carbohydrate in Mellin's Food is maltose, which seems to be particularly well adapted in the feeding of poorly nourished infants. Marked benefit may be expected by beginning with the above formula and gradually increasing the Mellin's Food until a gain in weight is observed. Relatively large amounts of Mellin's Food may be given, as maltose is immediately available nutrition. The limit of assimilation for maltose is much higher than other sugars, and the reason for increasing this energy-giving carbohydrate is the minimum amount of fat in the diet made necessary from the wellknown inability of marasmic infants to digest enough fat to satisfy their nutritive needs.

MELLIN'S FOOD COMPANY,

BOSTON, MASS.

WHEN A TONIC IS NEEDED

the best obtainable is called for-in its composition, in its quality and character, and above all, in its capacity to promote bodily vitality and strength. In

Gray's Glycerine Tonic Comp.

FORMULA DR. JOHN P. GRAY

the practitioner has at his command a restorative and reconstructive that justifies every confidence. Of the highest quality and constant uniformity-in spite of the drug market-and exceptional therapeutic efficiency, the use of "Grays" is a guarantee that the best possible results will be obtained in each and every case.

For over a quarter of a century “Grays" has been one of the most widelyand successfully-used remedies in atonic and debilitated conditions.

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chial inflammations so common during the winter. Cord. Ext. Ol. Morhuae Comp. (Hagee) is of exceptional palatability, a feature that makes it of unusual value in women and children. Its use should be continued throughout the winter in those susceptible to bronchial and pulmonary disease.

Persistent Coughs and Colds.-Colds that linger invariably owe their persistence to inability of the body to exert sufficient resistance to overcome germ activity. Recovery, in consequence, is always largely a question of raising the general vitality and increasing bodily resisting power. To accomplish this, no remedy at the command of the profession is SO promptly effective as Gray's Glycerine Tonic Comp. Under the use of this dependable restorative and reconstructive, the appetite is increased, the digestion improved, the nutritional balance restored, and the vital resistance so raised that the body can control infectious processes, and establish a safe and satisfactory convalescence.

In the treatment of colds, therefore, "Gray's" can be relied upon to raise the defensive forces of the organism and fortify it against germ attack.

Post-Operative Quiet. For the purpose of relieving nervous irritability and bringing about rest following a serious operation, the surgeon has at his command in Pasadyne (Daniel) a sedative agent of the greatest usefulness and one free from evil effects. Pasadyne (Daniel) is merely a distinctive name for a pure concentrated tincture of passiflora incarnate and is a product that has stood the test of nearly forty years. The advantages possessed by Pasadyne (Daniel) lie in its therapeutic potency and freedom from the properties that cause depression. Surgeons may depend upon it to secure for their patients the rest needed. A sample bottle of Pasadyne

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Pneumonia-

Prognosis-

Osler regards a slight or complete absence of leucocytosis as a very unfavorable sign in pneumonia.

Heart weakness due to the specific action of the poison, to the prolonged fever or to the overextension of the right chambers, is the important prognostic feature of the disease.

Antiphlogistine

increases leucocytosis; it relieves the heart by increasing the capillary circulation; it hastens the elimination of toxins, reduces the fever and relieves the dyspnoea and cyanosis. The use of Antiphlogistine in pneumonia is a most rational procedure; it is logical; it is reasonable, and it is scientific.

MAIN OFFICE AND LABORATORIES

THE DENVER CHEMICAL MFG. COMPANY NEW YORK, U. S. A.

Branches:

London, Sydney, Berlin, Paris, Buenos Aires, Barcelona, Montreal

MEDICAL SENTINEL

FEDERAL ANTI-NARCOTIC LAW

AND

GLYCO-HEROIN (SMITH)

The composition of Glyco-Heroin (Smith) is not being changed to meet any of the exemptions or privileges allowed under the so-called "Harrison Anti-Narcotic Law," and whereby it might be sold to the public.

Glyco-Heroin (Smith) will remain just what it always has been, and just what it was always intended to be, viz: a stable, un form and dependable product for the convenience and use of physicians only, in the treatment of Cough, Bronchitis, Whooping Cough, etc.

In prescribing Glyco-Heroin (Smith) use ordinary prescription blanks. Give the name and address of patient, your own name and address in full, your registry number and date when

written (no copy or other record required.)

PRESCRIPTIONS CANNOT BE

REFILLED

MARTIN H. SMITH CO., New York

The Most Effective Therapeutic Remedy for Nervous Diseases

In the treatment of many nervous diseases it not infrequently happens that the after-effects, or sequelae of the remedy are worse than the disease. This statement applies in particular to the bromides in the forms commonly employed. Valuable and effective as they are whenever a sedative or anti-spasmodic is needed, they must be prescribed with the utmost care and discretion, else the results, to put it mildly, may be unfortunate in the extreme.

The physician therefore, cannot be too critical and cautious in selecting the preparation of the bromides he uses, especially if it must be given for any considerable period. Many men know the advantages of Peacock's Bromides, but to those who do not, it should be pointed out that this high grade product easily stands

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and thorough elimination. I order 4 ounces of Tongaline, directing that two teaspoonfuls be taken in a half glass of water, preferably hot, every two hours for three or four doses, or until the patient is thoroughly under the influence of the medicine; then one teaspoonful every three hours, until the attack has been aborted or the patient has recovered. I have personally derived great benefit from Tongaline for 'colds,' taking it on the first appearance of any of the symptoms, and in nearly every instance abort the disease, and I use several bottles of Tongaline myself during the winter months in that way."

"Malt sugar is the most easily assimilated of all the sugars."

"Milk sugar and cane sugar require somewhat longer time for absorption than does malt sugar."

"Maltose may pass directly into the blood stream, and there be split up into its constituent dextrose molecules; maltase, the maltose-splitting enzyme, being present in the blood. Since lactase does not occur in the blood, any unsplit lactose introduced into the circulation as such is incapable of being utilized."

Maltose is the predominating carbohydrate in Mellin's Food.

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