FIRST INCEPTION OF COCA WINE - Coincident with the earliest scientific presentation in Europe, about 1859, of the physiological properties of coca by Dr. Mantegazza, and of the investigation of its chemical constituents by Professors Wochler and Niemann, and before the alkaloid cocaine had been described, Mr. Angelo Mariani, a pharmaceutical chemist, of Paris, France, prepared a wine from coca leaves which represented their full restorative qualities as employed in the Andes. This tonic-wine has ever since borne his name, and is known throughout the world by the proprietary title Vin Mariani. During nearly half a century this preparation of coca has been maintained of uniform excellence, with a distinctive quality that its numerous imitators have failed to approach. The reason of this must be obvious to the thoughtful. With the advance in improvements in various pharmaceutical processes, Mr. Mariani has adapted to his extensive manufacturing plant every means that might tend to keep the details of his product near to the high standard of his first ideal. This was the more earnestly desired because of the accumulated encouragement of thousands of practitioners who have endorsed Vin Mariani as a tonic of sterling worth.- The Coca Leaf, November, 1902.

DR. WALTER LINDLEY, the editor of the Southern California Practitioner, has recently been elected Dean of the Medical College of the University of Southern California. This Los Angeles school is now entering its twentieth session. Dr. Lindley was one of the organizers of the school and is Professor of Gynecology in that institution.

ENTEROCOLITIS AND CHOLERA INFANTUM Cleanse the intestinal tract with calomel and a saline, or with castor oil. Prescribe a suitable diet, easily digested and non-irritating. Irrigate the rectum and colon at suitable intervals with normal salt solution or some mild antiseptic, using for the purpose a soft rubber catheter or colon tube.

Instead of the opiates, which lock up the secretions and thereby favor auto-intoxication, relieve the muscular rigidity, and the excruciating pain which is such a drain upon the vital forces, by the use of antiphlogistine as hot as can be borne to the entire abdominal walls and covered with absorbent cotton and a compress. If the patient is not too far gone, the effect will be astonishing. The little sufferer, who until now has been tossing in agony and restlessness, with drawn features, will in most cases quickly become quiet; the drawn look will leave the face and a restful slumber will often supervene and start him upon the road to recovery. The explanation of this, in part, is not far to seek. The heat and moisture combined with antiphlogistine's well-known hygroscopic properties, directly soothe the inflamed parts, reflexly contracting the visceral bloodvessels and relieving their engorgement. The tension of the mus

cular and nervous systems is further relieved by the action of antiphlogistine through the solar plexus, thus adding to and emphasizing its local effects upon the inflamed intestines.

Beviews and Book Notices.

IMMUNE SERA, HAEMOLYSINS, CYTOTOXINS, AND PRECIPITINS, by A. Wasserman, M. D., of the University of Berlin; Translated by Charles Bolduan, M. D. 12mo. cloth, pp. 85. Price, $1.00. John Wiley & Sons, 43-45 E. 19th, St., New York, Publishers, 1904.

Those interested in Serum Diagnosis and Therapy will find in this translation of Prof. Wasserman's lectures some very interesting and valuable suggestions. He claims that it is but an introduction to the essentials of the subject. The book will be sent to any address postpaid, on receipt of the price.

THE MOTHER'S MANUAL, A Month by Month Guide for Young Mothers, by Emelyn L. Coolidge, M. D., Visiting Physician to the Out-Patient's Babies Hospital, New York; formerly House Physician to the Babies' Hospital, New York, etc., 12 mo., cloth, illustrated, pp. 263. Price $1.00, net. A. S. Barnes & Co., Publishers, New York, 1904.

This book presents with clearness and brevity precisely the information which every young mother asks.

It is a practical manual, indispensable in emergency, immediately helpful, and in touch with the most recent developments of modern science. It is absolutely trustworthy. Facts, rather than theories, are so lucidly arranged that they make it a handbook of permanent value.

A MANUAL OF CLINICAL DIAGNOSIS, by means of Microscopical and Chemical methods, for Students, Hospital Physicians, and Practitioners, by Charles E. Simon, M. D., of Baltimore. Fifth edition, thoroughly revised and enlarged. Illustrated with 150 engravings and 22 plates in colors. 8vo., cloth, pp. 695. Lea Bros. & Co., Publishers, Philadelphia, and New York, 1904.

The demand for a new edition has been considered by the author not only as an expression of professional approval, but also

as giving an opportunity of keeping his work up with the advances in this most important department of medical knowledge. His effort has been to give the best methods plainly and practically, in accordance with all needed instructions, and to render the work as modern and practical as possible. Besides a thorough and careful revision, this edition embodies much new matter that has been brought out in the literature of the past two years.

The blood, technique, methods of staining, leucocytosis, kryoscopy, with sections on paratyphoid fever, gonococcus septicemia, bubonic plague, trypanosomiasis, spotted fever, and other special features have claimed proper attention. Illustrations have been added whenever necessary to fully elucidate the text.

The book is dedicated to his wife, to whom the author expresses his acknowledgement for material aid, especially in the preparation of some very excellent plates.

A MANUAL OF FEVER NURSING, by Reynold Webb Wilcox, M. A., M. D., LL. D., Professor of Medicine in the New York Post-Graduate Medical School and Hospital; Consulting Physician to the Nassau Hospital; Fellow of the American Academy of Medicine, etc., etc. 8vo. cloth, pp. 236, price $1.00. P. Blakiston's Son & Co., Publishers, 1012 Walnut St., Philadelphia, Pa. 1904.

This little volume consists of the lectures on fever nursing which were delivered to the nurses of St. Mark's Hospital during the winter of 1903-4. The subject has been comprehensively and practically treated, and in accordance with the latest accepted views. Far more is to be accomplished by proper nursing than therapeutics in the management of most fevers, and we very consistently commend this little book.

CLINICAL TREATISE ON THE PATHOLOGY AND THERAPY OF DISORDERS OF METABOLISM AND NUTRITION. By Prof. Dr. Carl von Noorden, Senior Physician of the City Hospital in Frankfurt, a.M. Authorized American edition, translated under the direction of Boardman Reed, M. D. Part I., "Obesity: The Indications for Reduction Cures." 50 cents. New York: E. B. Treat & Company.

The first part of this book is devoted to simple obesity in persons otherwise healthy, considered in regard to its various degrees or stages. In the second part he takes up the compli

cations of obesity with other diseases, notably with diseases of the Circulatory System, Diseases of the Kidneys, Chronic Pulmonary Disease, Chronic Articular Rheumatism and Gout, Diseases of the Nervous System, Diabetes, and Pulmonary Tuberculosis. Nowhere else can the physician find so much thoroughly up-to-date information upon this important subject contained in so small a space.

A TEXT-BOOK OF MECHANO-THERAPY (massage and medical gymnastics). For Medical Students, Trained Nurses, and Medical Gymnasts. By Axel. V. Grafstrom, B. Sc., M. D., Attending Physician to the Gustavus Adolphus Orphanage, Jamestown, N. Y. Second edition, revised, enlarged, and entirely reset. 12m0 of 200 pages, fully illustrated. Philadelphia, New York, London: W. B. Saunders & Company, 1904. Cloth, $1.25 net.

The second edition of this useful little work has been entirely rewritten, reset, and very much enlarged. Two chapters have been added one on massage of the eye, ear nose, and throat, and the other on pelvic massage. Seventeen new illustrations have also been added. The author states that his object has been to present a work that would be useful as a text-book to students, trained nurses, and medical gymnasts, and as a reference book for the general practitioner, and in our opinion he has fully accomplished his purpose. It is certainly a practical and clear consideration of the subjects of massage and medical gymnastics, and it is with pleasure that we recommend it to our readers. The mechanical get-up is all that could be desired.

DISEASES OF THE Nose and THROAT, by D. Braden Kyle,, M. D., Professor of Laryngology and Rhinology, Jefferson Medical College, Philadelphia; Consulting Laryngologist and Rhinologist, and Otologist, St. Agnes' Hospital. Third edition, thoroughly revised and enlarged. Octavo volume of 669 pages, with 175 illustrations, and 6 chromo-lithographic plates. Cloth, $4.00 net; Sheep or Half Morrocco, $5.00 net. W. B. Saunders & Company, 1904, Philadelphia, New York, and London. In presenting to the profession the third edition of this work the general plan of the previous editions has not been materially altered. The entire book has been carefully revised and such. additions have been made as were rendered necessary by recent medical progress. The most important alterations and additions

have been made in the chapters on keratosis, epidemic influenza, Gersuny's paraffine method for the correction of nasal deformities, and in the one on the X-rays in the treatment of carcinoma. The etiology and treatment of hay fever have been partially rewritten and much enlarged, as has also the operative treatment of deformities of the nasal septum. In the chapter devoted to general considerations of mucous membranes and hay fever the author records the results of his experience in the chemistry of the saliva and nasal secretions in relation to diagnosis and treatment. The literature has been carefully reviewed, and a number of new illustrations added, thus bringing the work absolutely down to date.

OBSTETRIC AND GYNECOLOGIC NURSING, by Edward P. Davis, A. M., M. D.. Professor of Obstetrics in the Jefferson Medical College, and in the Philadelphia Polyclinic. 12mo volume of 402 pages, fully illustrated. Second edition, thoroughly revised. Polished Buckram, $1.75 net. W. B. Saunders & Company, 1904, Philadelphia, New York, and London.

The usefulness of this book to the nursing profession is manifest by the fact that a second edition has been called for. It is necessary for an obstetric nurse to possess some knowledge of natural pregnancy and its consequent diseases; and as gynecologic nursing is really a branch of surgical nursing, special training and instruction are required to meet the conditions arising. This book just fills the need, everything that the obstetric and gynecologic nurse should know being included. The second edition shows evidence of having been carefully revised throughout, and considerable new matter has been added. It would be well if every trained nurse possessed a copy of this book, for it certainly is of inestimable value.

EPILEPSY AND ITS TREATMENT, by William P. Spratling, M. D., Superintendent of the Craig Colony for Epileptics at Sonyea, N. Y. Handsome octavo volume of 522 pages, illustrated. Cloth, $4.00 net. W. B. Saunders & Company, 1904, Philadelphia, New York, and London. This work by Dr. Spratling is of unusual interest for many reasons: It is the first complete treatise on epilepsy since the apearance of Echeverria's work published over thirty-three years