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book will be found useful to many practitioners of medicine who may wish to keep themselves in touch with the development of modern physiology. For this class of readers references to literature are not only valuable, but frequently essential, since the limits of a text-book forbid an exhaustive discussion of many points of interest concerning which fuller information may be desired.
The numerous additions which are constantly being made to the literature of physiology and the closely related sciences make it a matter of difficulty to escape errors of statement in any elementary treatment of the subject. It cannot be hoped that this book will be found entirely free from defects of this character, but an earnest effort has been made to render it a reliable repository of the important facts and principles of physiology, and, moreover, to embody in it, so far as possible, the recent discoveries and tendencies which have so characterized the history of this science within the last few years.
CONTENTS OF VOLUME I.
trolling the flow of lymph, 75, 145— Pressure in lymph-vessels, 146– Effect of thoracic
General changes in the heart and arteries, 112— The heart and vessels in the open
nerves, 145—The nerve theory of the heart-beat. 149–The muscular theory of the
pensatory pause, 136.
Anatomical arrangement of the heart nerves, 159—The inhibitory nerves, 161-
Effect of inhibition on the ventricles 162– Effect of inhibition on the auricle and
sinus, 161-Effect of inhibition on the bulbus arterio-us, 165— Effect of inhibition on
the irritability of the heart. 16.5 - Relation of inhibition to rate and strength of stim-
ulus, 105– Arrest of the heart in spatole. 105-Comparative inhibitory power of the
two vagi, 166– Effect of the sptal nerves on the inhibition, 166— Theories of the
11 ture of vagus inhibition, 166--- Relation of age, temperature, and intracardiac press-
to inhibition. 167 - The augmentor or accelerator nerves of the heart, 167--- Effect
ulating the augmentor nerves. 169 -- Simultaneous stimulation of the accelerator
hibitors fibres, 170-Classification of the inhibitory and augmentor fibres. 171-
centripetal nerves of the heart, 17!-- Existence of sensory nerves in the heart,
Spongy structure of frog's heart, 179—The coronary arteries in the dog, 179—The
terminal nature of coronary arteries, 180—The effect of closure of the coronary arte-
ries, 181–The cause of the arrest of the heart after closure of the coronary arteries,
182—Fibrillary contractions and recovery from, 183—Closure of the coronary veins,
184–The volume of the coronary circulation, 184- The effect of the heart-contractions
on the coronary circulation, 185--The vessels of Thebesius and the coronary veins,
186—Blood-supply and heart-beat, 186--Lymuphatics of the heart, 186.
C. SOLUTIONS WHICH MAINTAIN THE BEAT OF THE HEART
Methods of nourishing the heart with solutions, 187--The composition and action of
nutrient solutions, 189--The effect of CO2, organic substances, and physical character-
istics of nutrient solutions, 191-Nourishment of tbe isolated mammalian heart, 191.
Part IV.-THE INNERVATION OF THE BLOOD-VESSELS (By W. T. Porter). .
Historical account of the discovery of vaso-inotor nerves, 192—Methods of demon-
strating vaso-motor phenomena, 195—Experimental distinctions between vaso-constric-
tor and vaso-dilator nerve-fibres, 196— Anatomical course of vaso-motor fibres, 197–
Vaso-motor centre in the medulla, 198–Vaso-motor centres in the spiual cord, 199
Sympathetic vaso-motor centres-peripheral tone, 200-Rhythmical changes in vascular
tone, 201— l'aso-motor retlexes, 201, 202, Relation of cerebrum to vaso-motor centres,
202—Pressor and depressor fibres, 202— Vaso-motor fibres to the brain, 203—Vaso-motor
fibres to the head, 204-Vaso-motor fibres to the lungs, 205--Vaso-motor fibres to the
heart, 206—Vaso-motor fibres to the intestines, 206—Vaso-motor fibres to the liver, 206
– Vaso-motor nerves of the kidney, 207– Vaso-motor nerves of the spleen, 207-- Vaso-
motor nerves of the pancreas, 207– Vaso-motor nerves of the external generative organs,
207---Vaso-motor nerves of the internal generative organs, 208—Vaso-motor nerves of
the portal system, 209–Vaso-motor nerves of the limbs, muscles, and tail, 209.
SECRETION (By W. H. HOWELL)
A. GENERAL CONSIDERATIONS
Definition of gland and secretion, 211–Types of glandular structure, 212–Older
views of secretion and excretion, 213-General proofs that gland cells take an active
part in secretion, 214--Filtration through living and dead tissues, 215.
B. MucOUS AND ALBUMIXOUS GLANDS-SALIVARY GLANDS
Distinction between mucous and albuminous glands, 215-Goblet cells as unicellular
mucous glands, 216– Anatomical relations of salivary glands, 217--Nerve-supply to
salivary glands, 218-Histology of salivary glands, 219-Composition of the saliva,
220-Siguificance of the potassium sulphocyanide in saliva, 221-Discovery of secre-
tory nerve-tibres to the salivary glands, 221-Distinction between “chorda" and
"sympathetic " saliva, 22:2—Effect of varying the strength of the stimulus upon the
composition of the saliva, 223--Theory of trophic and secretory fibres, 224 – Vacuoles
in gland cells during secretion, 2:26 — Histological changes in glands as a result of func-
tional activity, 226 - Action of atropin, pilocarpin, and nicotin on secretory fibres, 229
- The normal mechanism of salivary secretion, 230-Electrical changes in the salivary
glands during secretion, 231.
C. THE PANCREAS-GLANDS OF THE STOMACH AND INTESTINES .
Anatomical relations of the pancreas, 231-Histological characters of the pancreas,
231-Composition of the pancreatic secretion, 232-Secretory nerves of the pancreas,
232—Histological changes in pancreatic cells during secretion, 233—Distinction
between enzymes and zy mogens, 235 – The normal mechanism of the pancreatic secre-
tion, 235-The histological characteristics of the gastric glands, 237--Composition of
the gastric secretion, 238--Secretory nerves of the gastric glands, 239—The normal
mechanism of the gastric secretiou, 240-Histological changes in the gastric glands
during secretion, 242-The secretion of the intestinal glands, 243.
D. LIVER AND KIDNEY .
Histology of liver in relation to the bile-ducts, 244–Composition of the bile, 21.5—
The quantity of bile secreted, 246— Relation of the blood-flow to the secretion of bile,