In in A Text-Book of Materia Medica: cluding Laboratory Exercises the Histologic and Chemic Examinations f Drugs. For Pharmaceutic and Medical Schools, and for Home Study. By Robert A. Hatcher, Ph. G., M. D., Instructor in Pharmacology in Cornell University Medical School of New York City; and Torald Sollmann, M. D., Assistant Professor in Pharmacology and Materia Medica in the Medical Department of the Western Reserve University of Cleveland. 12mo volume of about 400 pages, illustrated. Philadelphia, New York, London: W. B. Saunders & Co., 1904. Flexible leather, $2.00, net. Students of medicine, as well as pharmacy students, will undoubtedly welcome this work. The authors are teachers of much experience, and in this forelying book present a work on the subject of Materia Medica in an entirely new way, teaching by actual experimental demonstration. Part I comprises a guide to the study of crude drugs, both official and unofficial; while in Parts II and III the histologic and chemic examinations of drugs are considered in a scientific, year clear and scientific manner. All the histologic descriptions are supplemented by laboratory exercises of important drugs, so that the student becomes insensibly acquainted with their construction. Throughout the entire work stress is laid on the recognition of adulterations. We can strongly recommend this work as reliable, practical, and excellent in every way. A Text-Book of Diseases of Women. By Charles B. Penrose, M. D., Ph. D., formerly Professor of Gynecology in the University of Pennsylvania. Fifth edition, thoroughly revised. Octavo volume of 539 pages, with 221 fine original illustrations. Philadelphia, New York, London: W. B. Saunders & Company, 1904. Cloth, $3.75, net. With astonishing regularity a new edition of this excellent text-book is called for, and it appears to be in as great favor with physicians as with students. Indeed, this book has taken its place as the ideal work for the general practitioner. The author presents the best teaching of modern gynecology, untrammelled by antiquated ideas and methods. In most instances only one plan of treatment is described. The new edition has been carefully revised, much new matter has been added, and a number of new original illustrations have been introduced. In its revised form this volume continues to be an admirable exposition of modern gynecology. The Youth's Companion in 1905. It is impossible even to summarize in a singe paragraph the many and varied attractions which The Youth's Companion announces for the coming year. A series of articles planned to interest especially the forty-five millions of Americans who look directly to the soil for their subsistence will treat of "New Fields for Young Farmers," "The Sanitation of the Farm," "The Future of American Cotton," "How Women Make Money on the Farm," etc. Seven serial stories and 250 short stories by the most talented and popular American writers of fiction will form part of the contents of the new volume for 1905. Full illustrated announcement describing the principal features of The Companion's new volume for 1905 will be sent with sample copies of the paper to any address free. The new subscriber who sends $1.75 now for a year's subscription to The Companion receives free all issues or The Companion for the remaining weeks of 1904, also The Companion "Carnations" Calender for 1905, lithographed in 12 colors and gold. THE YOUTH'S COMPANION, 144 Berkeley Street, Boston, Mass. Diseases of the Stomach and Intes- In presenting to the profession the third edition of this work the general plan of the previous editions has not been materially altered. The entire book has been carefully revised and such additions have been made as were rendered necessary by recent medical progress. The most important alterations and additions have been made in the chapters on Kera. tosis, Epidemic Influenza, Gersuny's Paraffine Method for the Correction Climatology in lof Nasal Deformities, and in the one on the X-rays in the Treatment of Carcinoma. The etiology and treat This octavo volume of 1024 pages Chent lo day Fever have been par its eighty-two lectures in covers com prehensively the Etiology, Pathology, Symptomatology, Diagnosis and Treatment of the various diseases in question, and presents the subject matter in a plain and attractive manner that renders the work so much more desirable. Such diseases as appendicitis, intestinal catarrh, dysentery and movable kidney are dealt with in the clear and simple way that gratifies the busy practitioner. The book has all the most modern methods of investigation and diagnosis, and is well worthy of commendation. Diseases of the Nose and Throat. By D. Braden Kyle, M. D., Professor of Laryngology and Rhinology, Jefferson Medical College, Philadelphia; Consulting Laryngologist, Rhinologist and Otologist, St. Agnes' Hospital. Third edition, thoroughly revised and enlarged. Octavo volume of 669 pages, with 175 illustrations, and six chromɔlithographic plates. Philadelphia, New York, London: W. B. Saunders & Company, 1904. Cloth, $4.00, net; Sheep or Half Morocco, $5.00, net. tially rewritten and much enlarged, as has also the operative treatment BOR Deformities of the Nasal Septum. In the chapter devoted to general considerations of Mucous Membranes and Hay Fever the author records the results of his experience in the chemistry of the saliva and nasal secretions in relation to diagnosis and treatment. The literature has been carefully reviewed, and a number of new illustrations added, thus bringing the work absolutely down to date. The Spectator counts Herbert Paul's tribute in The Contemporary to Sir William Harcourt by far the best appreciation yet written of the late leader of the Opposition, and particularly praises its judicial temperinsg of eulogy and criticism. The Living Age for December 3 reprints Mr. Paul's article entire. One of the most notable articles in The Quarterly Review bears the daring title, "The Advocatus Diaboli on the Divina Commedia." Dante-students will find it reprinted in The Living Age for December 3. Extracts The Efficacy of Antiseptics in the Treatment of Certain Conditions With Special Reference to the Merit of Glyco-Thymoline. By C. H. Powell, A. M., M. D., Profes- Ever since the introduction of Lord Lister's principles to the medical profession physicians have studiously and patiently investigated the many antiseptic agents introduced to their notice from time to time by different pharmaceutical establishments of recognized repute. Some of these preparations have not stood the test, and as a result "have fallen by the wayside." Others in proportion to their merit are filling an appropriate place in the prescription book. Of these there are but a very few indeed, and at the head of them all my experience induces me to place Glyco-Thymoline. This remedy, aside from possessing properties of a most positive nature, is handled by the Kress & Owen Company in a most ethical manner. The Medical Press is selected by this firm to the exclusion of all other mediums in order to keep the GlycoThymoline conspicuously before the profession. Not only that, but as a further evidence of the sincerity of the firm in believing their product all that is claimed, a liberal sample is sent to any physician who may desire to test Glyco-Thymoline. Without going further into the merits of this solution as an antiseptic possessing decided therapeutic properties, I desire to report two cases wherein by careful and persistent use this alka line, alterative solution has given me most excellent results. Case 1. Mrs. M. W., widowed, age 42, consulted me for nasal difficulty of several months' standing. An examination of the nasal fossae revealed several very interesting conditions. There were grouped together possibly seven or eight foci of ulceration, some of these spots ran together, presenting more or less of a serpiginous ulceration. Each ulcer was covered with a dirty gray ash colored exudate which adhered firmly to the underlying schneiderian membrane. I first applied on absorbent cotton a 50 per cent, solution of peroxide of hydrogen, and having removed the purulent secretion, sprayed the nose thoroughly with a 25 per cent. solution of Glyco-Thymoline in distilled water. I instructed the patient to report the day following for a renewal of the treatment, and to my surprise found a healthy-looking surface in place of a suppurating wound. I repeated the spraying of the nasal fossae some three or four times more, and complete healing took place, the nose returning to its normal condition within a week's time from the first application. Case 2. Mrs. F. K., maried, age 30, was brought to me for a disturbance of the throat, which, owing to the fact of a member of the lady's family having recently died of tubercular disease, was a source of much worry and mental anxiety to both the lady and her husband. The tonsils were somewhat congested, and showed upon their surfaces several little points of deposit dipping down into the tonsillar crypts. I immediately sprayed the tonsils with a full strength solution of Glyco-Thymoline, and at the same time gave the lady a six-ounce bottle 50 per cent. strength to use as a gargle. In three days' time she called to get some more of the solution, which she stated was very prompt in relieving her of her troublesome tickling sensation. Upon inspection I found the throat entirely cleansed of all exudates and the hyperaemic appearance of the tonsils was entirely removed, the gland assuming an almost normal hue. I again sprayed the tonsils with full strength Glyco-Thymoline, and instructed her to procure an original pound bottle from the drug store. She called again to see me in a few days, and stated she was entirely relieved of all unpleasant symptoms, and did not think further treatment was necessary. I accordingly dismissed her as cured. HYDROGEN PEROXIDE. How Breakage of Bottles Can Be Reduced to a Minimum. (Abstract from the National Druggist of St. Louis, Mo., October, 1904.) The greatest obstacle that lies in the way of producing a sound container for liquids occluding gases under high pressure, as, for instance, solutions of hydrogen peroxide, is the fact that no process for making unbreakable glass has yet been discovered. Up to the present, the ordinary amber glass bottles have been found totally inadequate and untrustworthy though a device patented by Mr. Charles Marchand goes far towards overcoming this delinquency. This device practically reduces the danger of bursting of the bottles to a minimum. As long as the bottles, having this device, are kept in stock standing up, the pressure resultin from shaking, high temperature in course of transit, etc., will not rise much above four or five pounds to the square inch; and, therefore, though occasionally a bottle may crack or burst, it is not due to pressure, but to the inherent imperfection of the glass, arising either from the lack of homogeneity, or else imperfect annealing, or both, to which we have already referred. The worst feature of this unreliability in the bottle is, that there is no accurate way of detecting it. A bottle may be submitted to a pressure of a hundred pounds to the square inch, without betraying signs of weakness, yet even with nothing in it, it may burst or crack within an hour. The only remedy in these conditions as to bottles, and that is not absolute, is in changing the material from which the containers are made, and substituting, for the unreliable amber glass, a good article of flint glass. While, as we have intimated, this does not absolutely remove the danger of loss by explosion or cracking, it greatly reduces it, and when the flint glass container is closed by Marchand's Safety Valve Stopper, danger is reduced to a minimum, beyond which, in the present condition of the technics of bottle-making, it is impossible to go. This is exactly what Mr. Charles Marchand, the manufacturer of hydrozone, glycozone, peroxide of hydrogen, etc., intends to do. Just as soon as his present stock of amber glass containers is exhausted, he will use exclusively flint glass, every bottle being corked with an automatic safety valve stopper. By adopting these expedients, Mr. Marchand, having done all in his power to prevent breakage, can go only one step further-to make good any losses from that directionreplace the bottles that get broken from this cause. Beyond this, it would be unreasonable to expect him actual danger to life or limb from the bursting of a bottle of hydrogen peroxide, or any of Mr. Marchand's preparations, is trivial, as compared with those arising from the explosion of bottles of beer, ginger ale, champagnes, and other sparkling wines, or even Apolinaris or other heavily aerated waters. When any of these rupture, the fragments are driven, not only with all the force and energy of the already liberated gases, but with the augmented energy of the residual gas suddenly set free, and SO may inflict severe, sometimes irreparable damage. The safety-valve arrangement in the stopper of bottles of hydrozone, prevents the sudden disengagement of a great volume of gas. Assuming that through some imperfection of the stopper, the puncture should close as soon as the pressure from within rose to a point far within that required for the rupture of the bottle, the stopper, not being wired, but merely tied down, will be forced out. But glass is a proverbially brittle and treacherous substance, and it is liable to break in the hands of anybody, at any moment, and without any discoverable or apparent cause, and that whether filled or not. As a consequence, there must always be some risk attached to the handling of glass containers. The best that can be done, as we have suggested elsewhere, is to reduce the risk of rupture or fracture to a minimum, and this Mr. Marchand has done, not only by his safety stopper device, but also by the promised substitution of the stronger flint glass. The retail trade will, we are sure, welcome this latter change most heartily, since it completes and supplements the efforts made in the mechanical direction, and thus removes, as far as it lies in human efforts, all danger arising from handling Marchand's goods. "GLUTEN GRITS." Farwell & Rhines' Latest, Unique, Sanitary Cereal. Through twenty years' experience in the manufacture and marketing of our "Gluten Flour," "Special Diabetic Food," "K. C. Whole Wheat Flour, and "Health Flour," for bread, biscuit, gems, griddle cakes, etc., we have realized the urgent demand for a thoroughly reliable, palatable and satisfactory Breakfast and Desert Cereal, for general use, which could be confidently and safely accepted and enjoyed by all who appreciate the Best and Purest in Cereal Foods. In our "Gluten Grits" we aim to answer this call. Incomparable in nutritive and dietetic worth. Invaluable as a Children's Food. Put up in 2-b cartoons, price 15 cents each. Directions for use on each package. Unlike all other goods. Trial proves their marked superiority. Saccharin Tablets may be used for sweetening in cases of Diabetes, Dyspepsia, Rheumatism, Obesity, etc., where sugar disagrees. One hundred and fifty times sweeter than sugar. Non-fermenting. Economical. In bottles, containing 100 tablets, 27c, or 500, $1.04, postage paid. We sell them. If not sold in your town, please write to Farwell & Rhines, Watertown, N. Y., U. S. A., for sample, and send name and address of your dealer, that we may supply him. A New Therapeutic Agent of Value in the Treatment of Epilepsy, With the Report of a Case. Hugo Erichsen, M. D., L. R. C. P. and S., reports an interesting case in |