and muscle pains without redness and very little swelling, remissions during the course of the attack, with eruptions, swelling of the glands, and profound prostration.

Differential Diagnosis.-Differential diagnosis must be made between dengue, influenza, and yellow fever.

Rheumatic fever may resemble dengue, the acid sweats, cardiac complications, the less severe onset, the symmetric involvement of the joints, with redness and swelling, all pointing to acute rheumatic fever.

Prognosis. The disease is rarely fatal.

Treatment. No specific treatment. A purge should be given at the onset and opium and its derivatives to relieve pain. Antipyretics may be of use. Administration of quinin is without avail. During convalescence the patient should have an abundant supply of nutritious food and tonics.

PERIODIC FEVERS.

MALARIA.

Definition.-Malaria is an infectious disease, characterized by periodicity of symptoms; anatomically, by enlargement of the spleen, and in the blood by the presence of the specific parasite.