Drug Discovery Strategies and Methods

Front Cover
CRC Press, 2003 M11 4 - 348 pages
Navigate the complex and multidisciplinary path of drug discovery procedures with Drug Discovery Strategies and Methods-a well-organized and timely reference that analyzes methods in target identification and validation, lead detection, compound optimization, and biological testing. This volume addresses challenges encountered during the discovery
 

Selected pages

Contents

Section 1
Section 2
Section 3
Section 4
Section 5
Section 6
iii
Section 7
ix
Section 8
ix
Section 18
12
Section 19
1
Section 20
38
Section 21
85
Section 22
8
Section 23
47
Section 24
25
Section 25
2

Section 9
ix
Section 10
xi
Section 11
xvii
Section 12
xxvii
Section 13
i
Section 14
viii
Section 15
xxx
Section 16
11
Section 17
37
Section 26
9
Section 27
12
Section 28
15
Section 29
15
Section 30
19
Section 31
20
Section 32
20
Section 33
20

Other editions - View all

Drug Discovery Strategies and Methods
Alexandros Makriyannis,Diane Biegel
Limited preview - 2003
Drug Discovery Strategies and Methods
Alexandros Makriyannis,Diane Biegel
Limited preview - 2003
Drug Discovery Strategies and Methods
Alexandros Makriyannis,Diane Biegel
No preview available - 2003

Common terms and phrases

Acad Sci USA activity agonist allosteric Alzheimer’s disease amide amines amino acid analogues anandamide antagonist antiviral atoms Balzarini Biochem Biol Chem C-terminal cannabimimetics cannabinoid receptor catalytic domain CB1 receptor cells Chem cleavage Clercq clinical complex compounds concentration conformational crystal structure crystallography derivatives drug design drug discovery effects endocannabinoid enhanced fibril formation Figure function human immunodeficiency virus hydrogen bonds hydrophobic immunodeficiency virus type inhibition inhibitors interactions isoxazole ligand linker Makriyannis marijuana Mechoulam membrane metabolic mice Mol Pharmacol molecular molecules muscarinic receptors mutation Natl Acad Sci neuronal NNRTIs nonpeptide novel opioid peptides opioid receptor Pertwee phase synthesis phenyl potent prion Proc Natl Acad protein pTyr pY+3 radioligand reaction residues resin reverse transcriptase Scheme Schiller PW selective SH2 domain signal transduction solid-phase synthesis specific stromelysin-1 studies target Tetrahedron Lett therapeutic TIPP Tyr1 viral vitro vivo x-ray

About the author (2003)

Alexandros Makriyannis University of Connecticut, Storrs, Connecticut, U.S.A.

Bibliographic information

TitleDrug Discovery Strategies and Methods
AuthorsAlexandros Makriyannis, Diane Biegel
PublisherCRC Press, 2003
ISBN1135523479, 9781135523473
Length348 pages
  
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