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augmented by the blood counts made by Dr. M. D. Hoge, Jr., Professor of Pathology in the University College of Medicine.

When it is remembered that the patients were all confined to bed; that they were recovering from the effects of serious surgical operations, and that they were subjected to the depressing influence of hospital life, the average increase of red blood corpuscles is remarkable. Had the cases been selected, and only anaemic patients tested, the results would have been showier.

CASE I. Miss E. G., aged 20; patient St. Luke's Hospital. Struck on back by windlass of well, four months prior to admission. Laminectomy and removal of carious bone and clotted blood. Gave Gude's Pepto-Mangan 60 days. First count, 1,500,000 red corpuscles to the cubic millimetre. Second count, 3,300,000 to the cubic millimetre. Rapidly improving, and recovery assured.

CASE II. Mrs. M. K., aged 29; patient St. Luke's Hospital. Cystic disease of ovaries and chronic inflammation of the appendix. Double Beattie-Tait, and appendectomy. Gave Gude's Pepto

Mangan 20 days. First count, 3,950,000 red corpusclea to the cubic millimetre. Second count, 4,000,000 to the cubic millimetre. Discharged well.

CASE III.-Miss C. H., aged 22; patient St. Luke's Hospital. History of frequent attacks of hepatic colic-no jaundice. Opened the gall-bladder and removed a calculus one inch in diameter. Gave Gude's Pepto-Mangan 28 days. First count, 3,940,000 red corpuscles to the cubic millimetre. Second count, 3,900,000 to the cubic millimetre. Bile still escaping from fistula, but patient otherwise well.

CASE IV.-Miss A. N., age 32 years; patient St. Luke's Hospital. History of sudden peritonitis, accompanied by profound sepsis. Exploratory incision revealed a pedunculated fibroid tumor of uterus, gangrenous from twisted pedicle. Myomectomy. Gave Gude's Pepto-Mangan 36 days. First count, 3,800,000 red corpuscles to the cubic millimetre. Second count, 4,000,000 to the cubic millimetre. Good recovery.

CASE V.-Miss E. J., aged 17; patient St. Luke's Hospital. Spinal irritation from a fall. Anaemic, emaciated, and confined to bed for more than a year from contraction of ham-string muscles. Electricity, massage and passive movements. Gave Gude's PeptoMangan 40 days. First count, 3,500,000 red corpuscles to the cubic millimetre. Second count, 4,425,000 to the cubic millimetre. Her menses, which had been suppressed, became regular. She fattened 20 pounds, and left the hospital walking with a cane.

CASE VI. Miss T. B., aged 21; patient St. Luke's Hospital. Retroverted uterus, bound down by adhesions. Opened abdomen,

freed organ and stitched it to anterior abdominal wall. Gave Gude's Pepto-Mangan 30 days. First count, 3,900,000 red corpuscles to the cubic millimetre. Second count, 3,950,000 to the cubic millimetre. Complete relief from spmptoms.

CASE VII.-Master D. S. J., aged 9; patient St. Luke's Hospital. Acute suppurative osteomyelitis of femur, tibia and tarsus on one side and of tibia and tarsus on the other. Amputated one limb and used chisel and curette on the other. Gave Gude's PeptoMangan 45 days. First count, 3,720,000 red corpuscles to the cubic millimetre. Second count, 4,600,000 to the cubic millimetre. Patient discharged with well healed stump, but incision in ankle still draining.

CASE VIII.-Mrs. H. E. W., aged 48; patient St. Luke's Hospital. Carcinoma of cervix; vaginal hysterectomy by clamp method. Had a bad liver and an irritable stomach, and though Pepto-Mangan was tried in varying doses, and at different times during convalescence, she was never able to take it for more than a day or two consecutively. First count, 3,400,000 red corpuscles to the cubic millimetre. Second count not made. Case made a slow recovery, but is now well.

CASE IX.-Master R. G., aged 14; patient St. Luke's Hospital. Compound depressed fracture of skull from a three-pound mass of type metal falling five stories. Trephined and removed blood clot and spiculae of bone. Gave Gude's Pepto-Mangan 21 days. First count, 3,900,000 red corpuscles to the cubic millimetre. Second count, 3,800,000 to the cubic millimetre. The loss was less than anticipated, as the boy was injured while in vigorous health. Recovery rapid and complete.

CASE X.-Miss A. E. S., aged 27; patient St. Luke's Hospital. Indigestion, constipation and dysmenorrhoea. Rapid dilatation of cervix. Gave Gude's Pepto-Mangan 34 days. First count, 3,900,000 red blood corpuscles to the cubic millimetre. Second count, 4,400,000 to the cubic millimetre. Bowels became regular, menstruation painless, and strength and weight increased.

CASE XI. Mrs. W. A. M., aged 29; patient St. Luke's Hospital. Symptoms of long-existing ovarian and uterine trouble, to which had recently been added those of inflammation of the appendix. On section, the uterus was found retroverted, the ovaries cystic, the appendix impacted and adherent, and the intestines filled. with lumbricoids. The uterus was righted and stitched to the anterior abdominal wall, the ovaries and appendix removed, and later a brisk purgative expelled the worms. Gave Gude's PeptoMangan 18 days. First count, 4,200,000 red corpuscles to the cubic millimetre. Second count, 4,310,000 to the cubic millimetre. Recovery and complete relief from symptoms.

CASE XII.—Mrs. L. A. W., aged 44; patient Virginia Hospital. Carcinoma of breast, with extensive lymphatic involvement. Radical extirpation of disease. Gave Gude's Pepto-Mangan 10 days. First count, 4,550,000 red corpuscles to the cubic millimetre. Second count, 4,620,000 to the cubic millimetre. Case discharged in two weeks and not heard from since.

CASE XIII. Mrs. L. J., aged 25; patient Virginia Hospital. Pyosalpinx, following puerperal septicaemia. Opened abdomen, freed numerous intestinal adhesions, enucleated pus tubes, and removed uterus by Baer's method. Gave Gude's Pepto-Mangan 28 days. First count, 3,410,000 red corpuscles to the cubic millimetre. Second count, 4,100,000 to the cubic millimetre. Perfect recovery.

CASE XIV.-Master J. F. S., aged 11; patient Virginia Hospital. Tuberculosis of the knee and femur, with secondary infection and profuse suppuration. Amputation. Gave Gude's PeptoMangan 24 days. First count, 4,005,000 red corpuscles to the cubic millimetre. Second count, 4,300,000 to the cubic millimetre. Rapid recovery and marked constitutional improvement.

CASE XV.-Miss A. H., aged 25; patient Virginia Hospital. Diseased ovaries and retroverted uterus. Double ovariotomy and ventro-suspension of uterus. Gave Gude's Pepto-Mangan 30 days. First count, 4,300,000 red corpuscles to the cubic millimetre. Second count, 4,200,000 to the cubic millimetre. Patient a hypochondriac and still complains.

CASE XVI. Mrs. E. B., aged 36; patient Virginia Hospital. Cirsoid aneurism of scalp and forehead, causing agonizing pain from involvement of orbit. Ligation of right common carotid artery. Gave Gude's Pepto-Mangan 16 days. First count, 4,400,000 red corpuscles to the cubic millimetre. Second count, 4,100,000 to the cubic millimetre. Force of pulsation diminished and pain completely relieved.

CASE XVII. Mr. P. S., aged 51; patient Virginia Hospital. Suppurative osteomyelitis of tibia. Amputation of limb. Gave Gude's Pepto-Mangan 28 days. First count, 3,400,000 red corpuscles to the cubic millimetre. Second count, 3,700,000 to the cubic millimetre. Recovery, with marked improvement in general health.

CASE XVIII.-Miss N. C., aged 30; patient Virginia Hospital. Rapidly growing fibroid tumor of uterus. Complete hysterectomy and removal of mass weighing forty pounds. Gave Gude's PeptoMangan 30 days. First count, 3,700,000 red corpuscles to the cubic millimetre. Second count, 3,750,000 to the cubic millimetre. Intercurrent attack of pneumonia, which retarded recovery and interfered with the regular administration of medicine.

CASE XIX.-Mrs. S. S., aged 50; patient Virginia Hospital. Carcinoma of breast. Amputated organ and dissected out adjacent

lymphatic glands. Gave Gude's Pepto-Mangan 10 days. First count, 4,200,000 red corpuscles to the cubic millimetre. Second count, 4,250,000 to the cubic millimetre. No report from case since discharge.

CASE XX.-Mrs. J. S., aged 31; patient Virginia Hospital. History of three acute attacks of appendicitis. Thin, anaemic and nervous. Appendectomy. Gave Gude's Pepto-Mangan 26 days. First count, 2,644,000 red corpuscles to the cubic millimetre. Second count, 3,950,000 to the cubic millimetre. Gained fifteen or twenty pounds in weight and is completely well.

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