a quiescent stage after the discharge, absorption or inspiration of the abscess contents, or when formed cavities become clean and dry. Usually, however, the tendency is to successive eruptions of tubercles during or soon succeeding excavation.

Phthisis, in a strictly pathologic sense, does not begin until the caseous tubercles commence to soften and break down. Acute diseases occurring during a latent tuberculosis are frequently followed by phthisis, since they check the natural encapsulating process of cure and set up liquefactive changes.

Toward the fatal end of phthisis the pathologic changes may include a variety of lesions, such as miliary tuberculosis; caseous, fibroid and calcareous degeneration; pneumonic infiltration; bronchial catarrh and ulceration; areas softening into excavations; and open and closed cavities in all stages of inflammation, ulceration and cicatrization.

The common associated changes of chronic ulcerative phthisis are catarrhal pneumonia, broncho pneumonia, purulent bronchial catarrh and pleuritis, and proliferation of the interstitial connective tissue. Pneumonias from mixed infection are markedly severe, causing a rapid advance of the tubercular disease and early decline. Tubercular children are particularly liable to attacks of localized pneumonia around the tubercular area.

The acute miliary, pneumonic and bronchopneumonic types, the ordinary caseous tuberculosis (chronic ulcerative phthisis), and the chronic fibroid form of the disease, represent, generally speaking, different degrees of infection and of individual resistance and reaction.

EDITORIAL ITEMS.

Idiopathic Amenorrhea.-Bushong recomends manganese binoxid in pill form in the dose of one to four grains three times a day.

Menopausal Menorrhagia.-Fordyce Barker employed rectal suppositories of 3 1-3 grains of aqueous extract of ergot thrice daily, for a week previous to the return of the expected period.

Menorrhagia of Chronic Endomertitis.—Thorough curettage often affects a cure. H. A. Davidson recommends local galvanization, with the positive pole in the uterus.

Tachycardia of Arteriosclerosis.-Vires (Medical Press) gives two grains of extract of convallaria and one grain of sparteine sulphate daily in pills.

Sudden Suppression of Menses from Chill.-Ringer recommends tincture of aconite, one drop every half hour or hour.

Uterine Hemorrhage for Pelvic Congestion.-In some cases, says Hare, dry cups over the sacrum give relief.

Menorrhagia from Atony of Uterus.—Potter prescribes one grain of extract of ergot and one-half grain extract of opium every hour for profuse menstruation.

American Medical. The next meeting of the American Medical Association will be held at New Orleans May 5th, 6th, 7th and 8th, 1903.

The Presbyterian Hospital of Philadelphia has received a gift of $30,000 from an anonymous donor for the purpose of building a new maternity house.

Respiration.-Guenther states that it may easily be calculated that man in 24 hours respires about 10,800 litres of air, which is equal to a space 7 1-3 feet in three dimensions.

Menorrhagia of Systemic Origin.-When occurring in young subjects, Hare advises potassium bromide, five or ten grains night and morning for a week before expected period.

Myomatous Metrorrhagia.-According to Brickner, the fluid extract of hydrastis candensis three or four times a day, controls irregular bleeding as a rule without resort to further measures.

Amenorrhea of Obesity.-Lustand prescribes a cachet twice or thrice daily containing 11⁄2 grains aloes and 1⁄2 grain each of rue, savin and saffron.

Editorial Items continued on Page 466

BOOKS.

LEA'S SERIES OF MEDICAL EPITOMES. MANTON'S ORSTETRICSA Manual of Obstetrics for Students and Practitioners. By W. P. Manton, M. D., Adjunct-Professor of Obstetrics and Professor of Clinical Gynecology, Detroit College of Medicine. In one 12mo. volume of 265 pages, with 82 illustrations. Cloth, $1.00. Lea Brothers & Co., Publishers, Philadelphia and New York, 1903.

This brief manual, with its 265 pages and 82 illustrations, is a good example of skillful condensation, containing a surprising amount of simply told and clearly connected information on the essentials of obstetrics. For convenience in quizzing, a series of questions are furnished at the end of each chapter.

LEA'S SERIES OF MEDICAL EPITOMES.-An Epitome of Physiology for Students and Practitioners of Medicine. By Theodore C. Guenther, M. D., of the Norwegian Hospital, Brooklyn, and Augustus E. Guenther, B. S., formerly Assistant in Physiology in the University of Michigan, Ann Arbor. In one 12mo volume of 250 pages, with 57 engravings. Cloth, $1.00, net. Lea Brothers & Co., Publishers, Philadelphia and New York, 1903.

This epitome is quite up to date. It is compactly written, carefully compiled and systematically arranged. Free use is made of italics in emphasizing important points. The ground of each chapter is well covered by questions at the end. The book is entirely suitable to the needs of medical and dental students.

INTERNATIONAL CLINICS.-A Quarterly of Illustrated Clinical

Lectures and Especially Prepared Articles on Medicine, Neurology, Surgery, Threapeutics, Obstetrics, Pediatrics, Pathology, Dermatology, Diseases of Eye, Ear, Nose and Throat, and Other Topics of Interest to Students and Practitioners. By Leading Members of the Medical Profession Throughout the World. Edited by Henry W. Cattell, A. M., M. D., Philadelphia. Volume IV. Twelfth Series. 1903. Philadelphia: J. B. Lippincott Company.

The demand for International Clinics has become so great, we understand, as to be difficult to fulfill. The present number has the usual quota of timely, interesting and instructive contributions. The first article, on "The Sanatory Tent and Its Use in the Treatment of Pulmonary Tuberculosis," by Charles Fox Gardiner, is of special interest to Colorado practitioners. Another helpful article is that on the differential diagnosis between tuberculosis of the lungs and diseases which resemble it, by Lawrence F. Flick. In a clinical lecture on scars and marks of clinical interest, Dr. J. N. Hall brings out a number of practical points with striking effect. Thomas R. Brown contributes an exhaustive monograph on the blood in health and in disease with a review of the recent important work on this subject.

THE PRACTICAL MEDICINE SERIES OF YEAR BOOKS-Comprising Ten Volumes on the Year's Progress in Medicine and Surgery. Issued monthly under the general editorial charge of Gustavus P. Head, M. D., Professor of Laryngology and Rhinology, Chicago Post-Graduate Medical School. Volume III. The Eye, Ear, Nose and Throat. December, 1902, Chicago. The Year Book, Publishers, 40 Dearborn Street. The year's progress of medicine in these three specialties is herein clearly and fairly outlined by Drs. Casey A. Wood (on the eye), Albert H. Andrews (on the ear) and T. Melville Hardie (nose and throat). The text comprises 309 pages, with 35 figures. The book is well printed on good paper. This series appears now to be an established success, and the issuance of a volume each month is very convenient for the busy practitioner.

SELECTIONS.

NEW ORLEANS POLYCLINIC.-Sixteenth annual session opens November 3, 1902, and closes May 30, 1903. Physicians will find the Polyclinic an excellent means for posting themselves upon modern progress in all branches of medicine and surgery. The specialties are fully taught, including laboratory work. For further information address New Orleans Polyclinic, Postoffice Box 797, New Orleans, La.

QUICK AND SURE AND TIME TRIED.-Many of our doctor friends will recognize in the following, from Chas. B. Forsyth, M. D. (Belle. Hosp. Med. Col., N. Y. City), dated Alexandria Bay, N. Y., Jan. 6th, '03, an expression which will recall their own experience. He says: "I can say no more than that I have used Antikamnia Tablets since I began practicing medicine. Several times I have switched to other preparations, but I invariably come back to Antikamnia Tablets."

The Antikamnia Chemical Company, St. Louis, Mo., is an old and responsible concern, and any of their specialties may be depended upon. The latest additions to their list are "Antikamnia and Heroin Tablets" and "Laxative Antikamnia and Quinine Tablets." Send for samples, mentioning "DENVER MEDICAL TIMES.

STEARNS' ANTITOXIN.-The expense of keeping a serum syringe for the administration of antitoxin is done away with by the employment of Stearns 'Antitoxin, which comes in the SyroBulb, from which it is injected just as from a syringe. An absolutely aseptic package and a product of high potency make it well worth the practician's while to give his preference to Stearns' Antitoxin.

SANMETTO IN ENLARGED PROSTATE COMPLICATED WITH CYSTITIS. Dr. J. M. Minick of Wichita, Kan., president of the Kansas State Board of Health, reporting his experience with Sanmetto, says: "I do not explain the action of Sanmetto from any ulterior motive or for publication any further than I candidly believe it is a God-send to men who are afflicted with enlarged prostate gland complicated with chronic cystitis, with a constant desire to micturate, especially at night."

PONCA COMPOUND. "I gave Ponca Compound a crucial test for an obstinate case of leucorrhoea of such long standing