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ERY, Report to the Wisconsin State Medi.., of Milwaukee, Chairman of the Commit--by the Sentinel Company, 1881.

"OR, for storing dynamical electricity for poses, by LOUIS ELSBERG, A. M., M. D. weirth street, 1881.

SURGEON GENERAL OF THE UNITED

THE

Chicago Medical Times.

WILSON H. DAVIS, M. D.,

Editor and Publisher.

No. 11.

VOL. XIII. CHICAGO, FEBRUARY, 1882.

ORIGINAL COMMUNICATIONS.

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PSEUDO-LEUCOCYTHÆMIA.

PROF. H. S. TUCKER, DEMOSTRATOR OF ANATOMY,

MEDICAL COLLEGE.

BENNETT

An affection in which anatomical changes, similar to those in leucocythæmia, are present, but without the variation in the relative proportion of the white and red blood globules.

My attention has been more especially directed to this comparatively rare affection by discovering unmistakable evidence of its having existed in a subject, which at the present writing is in the dissecting room of Bennett Medical College,

The anatomical changes which are characteristic of this disease are enlargement of the spleen, with the development of nodules, which are hypertrophied malpighian follicles, and also more or less enlargement of the lymphatics throughout the body.

In the case above mentioned, the spleen was greatly enlarged, weighing fifty-one ounces. The pancreas was also enlarged. The cervical, dorsal, lumbar and axillary glands were found to be similarly affected, varying in size from that of a pea to an English walnut.

The cut surface of an enlarged lymphatic, under the micro

out in book form, the first edition was speedily exhausted, and a second demanded. The book gives us a very good conception of the field occupied by electro-therapeutics, and brings out some points not touched upon by larger works. The use of Franklinic or static electricity is at the present time attracting much attention, and Dr. Rockwell's chapter on this subject will be read with interest.

SUPPRESSION OF URINE, clinical descriptions and analysis of symptoms, by E. P. FOWLER, M. D., ninety-three clinical cases, with illustrations, tables and diagrams. New York: William Wood & Co., 1881. Chicago: Jansen, McClurg & Co.

A very interesting work and one which shows great labor and pains-taking research on the part of the writer. It forms a valuable contribution to medical science.

WALSH'S PHYSICIANS' COMBINED CALL-BOOK AND TABLET. Sixth edition, published by RALPH WALSH, M. D., 332 C Street, Washington, D. C., mailed prepaid, upon receipt of $1.50.

In some respects, this book surpasses the visiting lists already noticed. It is of a very convenient size and shape, 74x4, and only of an inch in thickness. It is good for any year or portion of a year, and contains a choice selection of printed matter.

WALSH'S PHYSICIANS' HANDY LEDGER, a companion to the Call-Book and Tablet, published by RALPH WALSH, M. D., 332 C Street, Washington D. C., mailed prepaid, upon receipt of $3.50.

A day book and ledger combined, constructed upon a plan so simple and practical, that little time is required to keep the details of a large practice posted up. We have had one in use for three years, and find it a very great saving of time and labor.

THE STUDENTS' MANUAL OF VENEREAL DISEASES, being a concise description of those affections and of their treatment, by BERKLEY HILL, Professor of Clinical Surgery in University College, London, etc., and by ARTHUR COOPER, late Surgeon to the Lock Hospital. Second edition, New York: William Wood & Co., 1881. Chicago: Jansen, McClurg & Co. Price, 10 cents.

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RECENT PROGRESS IN SURGERY, Report to the Wisconsin State Medical Society, by N. SENN, M. D., of Milwaukee, Chairman of the Committee. Milwaukee: Printed by the Sentinel Company, 1881.

THE GALVANIC ACCUMULATOR, for storing dynamical electricity for cautery and illuminating purposes, by Louis ELSBERG, A. M., M. D. New York: 201 to 213 East Twelfth street, 1881.

ANNUAL REPORT OF THE SURGEON GENERAL OF THE UNITED STATES ARMY, 1881.

MANSILLS' ALMANAC AND WEATHER GUIDE, Price 25 cents. R.

THE

Chicago Medical Times.

WILSON H. DAVIS, M. D.,

Editor and Publisher.

VOL. XIII. CHICAGO, FEBRUARY, 1882.

No. 11.

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An affection in which anatomical changes, similar to those in leucocythæmia, are present, but without the variation in the relative proportion of the white and red blood globules.

My attention has been more especially directed to this comparatively rare affection by discovering unmistakable evidence of its having existed in a subject, which at the present writing is in the dissecting room of Bennett Medical College,

The anatomical changes which are characteristic of this disease are enlargement of the spleen, with the development of nodules, which are hypertrophied malpighian follicles, and also more or less enlargement of the lymphatics throughout the body.

In the case above mentioned, the spleen was greatly enlarged, weighing fifty-one ounces. The pancreas was also enlarged. The cervical, dorsal, lumbar and axillary glands were found to be similarly affected, varying in size from that of a pea to an English walnut.

The cut surface of an enlarged lymphatic, under the micro

velopment of a delicate reticulum, with wide meshes. The distinction between the cortex and medulla is usually obliterated.

In the majority of cases, the affection commences in the cervical glands, and attacks by preference the glands in the vicinity of the great blood vessels. Why this should be so, with our present knowledge, it would be difficult to decide, as we do not know what changes in the blood are necessary to affect the nutrition of the lymphoid cells by altering their relation with the cell-fluid or blastema.

The bronchial glands in the subject under discussion were enlarged to a great extent, and, judging from the post mortem appearances, must have produced considerable pressure on the air passages, interfering somewhat with respiration.

As no section was made of the bones, cannot say just what changes might be apparent should such section be made; but should expect to discover, where the spleen and lymphatics are involved to such an extent, lymphoma developed in the medullary substance.

The spleen had whitish growths disseminated throughout its substance, which are hypertrophied malpighian follicles and growths in the sheaths around the blood vessels.

These growths were also found pretty generally distributed throughout the peritoneum at the posterior part of the abdominal cavity. Pseudo-leucocythæmia includes splenic anæmia, lymphatic anæmia, and at least some cases of pernicious anæmia.

The duration of the disease is variable, in some cases lasting but a few weeks, and in other cases years.

In the majority of cases, it occurs in persons between the ages of ten and thirty, and is developed more often in the male than in the female.

The development of the disease is usually slow and imperceptible-general debility and disordered digestion and other indefinite ailments may have been apparent for one or two years. In exceptional cases, it may have been developed in a few weeks. With the occurrence of anæmic symptoms, we

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