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Pilula

ANTIPERIODICE (Warburg's Pills).—1. With Aloes: Aqueous
Extract of Aloes, grain 1 (0.06); Rhubarb, grain 1 (0.03);
Elecampane, Saffron, Fennel, each, grain (0.015); Zedo-
ary, Cubebs, Myrrh, White Agaric, Camphor, each, grain
(0.008); Quinine Sulphate, grains 1 (0.085); Extract of
Gentian, a sufficient quantity.

2. Without Aloes: The same formula as above, with omission of the Aqueous Extract of Aloes. These pills have been introduced for the purpose of facilitating the administration of Warburg's Tincture in a solid form. When "Warburg's Pills" or "Pills of Warburg's Tincture" are prescribed, without further specification, those containing Aloes are recommended to be dispensed-those without Aloes only when they are expressly demanded.

Each Warburg's Pill represents about 1 fluidrachm (4) Cc.) of Warburg's Tincture. (See Tinctura Antiperiodica.) COLOCYNTHIDIS COMPOSITE (Pilulæ Cochia).-Extract of Colocynth, grain (001); Aloes, Resin of Scammony, of each, grains 2 (0.13); Oil of Cloves, min. † (0.015). COLOCYNTHIDIS ET HYOSCYAMI.-Extract of Colocynth, grain

(0.006); Aloes, Resin of Scammony, Ext. Hyoscyamus,
each, grains 1 (0.1); Oil of Cloves, min. (0.01).
COLOCYNTHIDIS ET PODOPHYLLI.-Compound Extract of Colo-
cynth, grains 1 (0.16); Resin of Podophyllum, grain
(0.015).

FERRI COMPOSITE (U. S. P. 1880).-Myrrh, 1 grains (0.1);
Ferrous Sulphate, Sodium Carbonate, each, grains (0.048).
GALBANI COMPOSITE (U. S. P. 1880).-Galbanum, Myrrh,
each, 1 grains (0.1); Asafoetida, grain (0.03).

GLONOINI (Nitroglycerin).—Spirit of Glonoin (1 per cent.),
Athæa, each, grains 200 (13.0); Confection of Rose, a suf-
ficient quantity. Make a mass and divide it into two hun-
dred (200) pills. Each pill contains grain (0.0007) of
Glonoin (Nitro-glycerin).

LAXATIVE POST-PARTUM (Barker's).—Ext. Colocynth. Comp., grains 1 (0.1); Aloes, grain & (0.05); Res. Podoph., Ipecac., each, grain (0.005); Ext. Nux Vomica, grain (0.03); Ext. Hyoscyamus, 14 grains (0.8).

This is the formula generally employed by Dr. Fordyce Barker, except where special circumstances render modi

Pilula

fications necessary. The formula usually quoted in manufacturers' lists and some formularies is not correct. METALLORUM (Metallorum Amara).- Reduced Iron and Quinine Sulphate, each, grain I (0.06); Strychnine and Arsenous Acid, of each, grain

(0.003).

Aitken's Tonic Pill is a similar combination:

Reduced Iron, grain

(0.04); Quinine Sulphate, grain 1

(0.06); Strychnine, Arsenous Acid, each, grain (0.0012). OPII ET CAMPHORE.-Powdered Opium, I grain (0.06); Camphor, grains 2 (0.13).

OPII ET PLUMBI.-Powdered Opium and Acetate of Lead,
each, grain I (0.06).
PODOPHYLLI, BelladonnÆ et CAPSICI (Squibb's Podophyllum
Pills).-Resin Podophyllum, grain (0.015); Capsicum,
grain (0.03); Ext. Bellad. Alc., grain (0.008); Sugar of
Milk, grain 1 (0.06); Acacia, Glycerin, and Syrup, each,
a sufficient quantity.
QUADRUPLICES (Ferri et Quininæ Compositæ).-Ferrous Sul-
phate, Quinine Sulphate, Aloes, each, grain 1 (0.06); Ext.
Nux Vomica, grain (0.015); Ext. Gentian, sufficient.
TRIPLICES (Triplex).—Aloes, grains 2 (0.13); Resin Podo-
phyllum, grain (0.015); Mass of Mercury, grain 1 (0.06).

When Pilula Triplex, under this name or some equiva-
lent, is prescribed without further specification, the N. F.
recommends that the above preparation be dispensed. A
formula devised by John W. Francis is also in use:
2. Francis's Triplex Pill.-Aloes, Scammony, Mass of
Mercury, of each, grain (0.05); Croton Oil, min. (0.003);
Oil of Caraway, grain

(0.015); Tincture of Aloes and

Myrrh, a sufficient quantity.

UNOFFICIAL FORMS OF MIXTURES OF SOLIDS FOR INTERNAL

USE.

Granules are small pills, less than I grain (0.06) in weight, usually sugar-coated and containing alkaloids and other active drugs.

Parvules are identical with granules. They are usually colored red or pink.

Globules (Orbicula) are sugar pellets to be saturated with alcoholic solutions of medicinal agents, chiefly in Homœopathy.

Compressed Pills are made by compressing powders into disks not exceeding 5 grains (0.3) in weight, without any excipient.

Friable Pills are made by aggregation, spreading the powdered mixture upon nuclei or sugar granules in a revolving pan until the pills are formed.

Bolus is the name given to pills exceeding 5-10 grains (0.3-0.6) in weight, used in veterinary practice. A sugar-coated bolus is called a Dragee.

Rotula are disk-shaped forms of sugar about 1 grains (0.1) in weight, which may be flavored with alcoholic solution (spirits).

Bacilli are cylindrical sticks, a form of lozenge (Licorice). Lamelle, thin squares of gelatin in which the active agent has been incorporated, intended for solution in the eye.

PREPARATIONS FOR EXTERNAL USE.

To this group belong the liquid preparations: Liniments, Oleates and Collodions, and the mixtures of solids: Ointments, Cerates, Suppositories, Plasters, and Papers. The Vehicle, sometimes incorrectly called the "base," consists chiefly of fatty substances which serve as protectives or facilitate absorption. The Collodions are, however, an exception.

The solid mixtures may be classified according to their fusibility, or melting-points, because their therapeutic uses, as well as their pharmaceutical forms, are through this quality respectively determined.

Ointments fuse at the body-temperature, and therefore produce an emollient effect, or induce absorption of the medicinal substance by the system. They are applied by rubbing or inunction.

Cerates have a higher fusing-point, due to Wax they contain; the medicinal agent is not so readily absorbed, and they are therefore used to produce local effects, being spread on cloth and applied as dressings.

Suppositories have the same fusibility as cerates, and may be said to be cerates intended for application to the orifices of the body, both for absorption and local effect.

Plasters have a still higher fusibility; they do not melt, but become adhesive by the body-temperature, and are intended to produce local effects and afford mechanical support to the parts affected.

The fusibilities of these various preparations are likewise governed by the respective vehicles employed.

LINIMENTA-LINIMENTS.

The Liniments are liquid preparations for external use, consisting of solutions of oily or resinous constituents in Alcohol or Oils, or mixtures of liquid Soaps. The nine official Liniments are prepared by simple admixture or solution.

Linimentum—

Ammonia.

cotton seed oil 60 Cc.; ammonia water 35 Cc.; alcohol 5 Cc.

Belladonnæ
Calcis (Carron Oil)
Camphoræ .
Chloroformi
Saponis

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fl. ext. belladonna 95 Cc.; camphor 5 Gm. .. linseed oil 50 Cc.; lime solution 50 Cc. cotton seed oil 80 Gm.; camphor 20 Gm.

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soap liniment 70 Cc.; chloroform 30 Cc. camphor 4.5, soap 7,

rosemary oil I; alcohol 75; water, to 100 Cc. Saponis Mollis, alcohol 35 Cc.; lavender oil 2; soft soap 65 Gm. Sinapis Comp. . . fl. ext. mezereum 20; mustard oil, vol. 3, camphor 6; castor oil 15; alcohol, to 100 Cc. resin cerate 65 Gm.; turpentine oil 35 Gm.

Terebinthinæ.

Unofficial Liniments of the National Formulary.

Linimentum

ACONITI ET CHLOROFORMI.-Tincture of Aconite, Chloroform,
each, 2 fluidounces (60 Cc.); Soap Liniment, 12 fluidounces
(355 Cc.).
AMMONII IODIDI.-Iodine, 30 grains (2.); Oil of Rosemary,
Oil of Lavender, each, 110 minims (7 Cc.); Camphor, 220
grains (15.); Water of Ammonia, 1 fluidounces (50 Cc.);
Alcohol, enough to make 16 fluidounces (473.17 Cc.). On
standing, it becomes colorless.

CANTHARIDIS (U. S. P. 1880).—Oil of Turpentine containing
15 per cent. of Cantharides.

IODI (similar to Ph. Br.).—Iodine, 900 grains (60.); Potassium

Iodide, 360 grains (24.); Glycerin, fluidounce (15 Cc.); Water, I fluidounce (30 Cc.); Alcohol, enough to make 16 fluidounces (473.17 Cc.).

OPII COMPOSITUM (Canada Liniment).-Tincture of Opium, 1 fluidounces (45 Cc.); Camphor, 120 grains (8.); Alcohol, 4 fluidounces (118 Cc.); Oil of Peppermint, 180 minims.

Linimentum

(12 Cc.); Water of Ammonia, 6 fluidounces (180 Cc.);
Oil of Turpentine, enough to make 16 fluidounces.
(473.17 Cc.).

PLUMBI SUBACETATIS (U. S. P. 1880).—Solution of Lead Sub-
acetate, 35 parts; Cotton Seed Oil, 65 parts.
SAPONATO-CAMPHORATUM (Opodeldoc; Solid Opodeldoc).—
White Castile Soap, 1 ounces (45.); Camphor, ounce
(15.); Alcohol, 20 fluidounces (592 Cc.); Oil of Thyme, 30
minims (2 Cc.); Oil of Rosemary, 60 minims (4 Cc.); Water
of Ammonia, Fort., I fluidounce (30 Cc.).
TEREBINTHINÆ ACETICUM (Linimentum Album., Stokes' Lini-
ment; St. John Long's Liniment).-Oil of Turpentine, 3
fluidounces (89 Cc.); Fresh Egg, 1; Oil of Lemon, 60
minims (4 Cc.); Acetic Acid, 300 minims (20 Cc.); Rose
Water, 2 fluidounces (75 Cc.).

TIGLII (Linimentum Crotonis, Ph. Br.).-Croton Oil, 2 fluid-
drachms (8 Cc.); Oil of Cajuput, 7 fluidrachms (27.5
Cc.).

TIGLII COMPOSITUM.-Croton Oil, I fluidounce (30 Cc.); Oil of Sassafras, 1 fluidounce (30 Cc.); Oil of Turpentine, I fluidounce (30 Cc.); Oil of Olive, 2 fluidounces (60 Cc.).

Lotio

LOTIONES-WASHES.

ADSTRINGENS (Warren's Styptic).-A mixture of Sulphuric
Acid, Oil of Turpentine, and Alcohol.

FLAVA (Yellow Wash, Aqua Phagedænica Flava, Ph. Ger.).
-Corrosive Mercuric Chloride, 24 grains (1.5), in Lime
Water, 16 fluidounces (473 Cc.).

NIGRA (Black Wash; Aqua Phagedænica Nigra, Ph. Ger.).
-Mild Mercurous Chloride, 64 grains (4.), in Lime Water,
16 fluidounces (473 Cc.).

PLUMBI ET OPII (Lead-and-Opium Wash).-Lead Acetate, 120 grains (8.); Tincture of Opium, fluidounce (15 Cc.);

in Water, 16 fluidounces (473 Cc.). To be shaken when dispensed.

The following are unofficial solutions and mixtures for external

use:

Injectio, -ones-Aqueous solutions for introduction by means of a syringe in the orifices of the body.

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