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sumptives at Blackwell's Island. The book is well worth a perusal by those interested in consumption, but we fear the redfaced, robust Irishman will hardly agree with the author when he says: "It would be a blessing to the race if potatoes were banished from the planet and the more easily-digested rice substituted." Nor do we think our hardy lumbermen in the backwoods will agree with the quotation adopted from Dr. Kellogg, in which he says: "Hogs are very prone to tuberculosis, and that a slice of fat pork is concentrated, consolidated filth.

W. J. W.,

A Compound of Pathology, General and Special. A Student's Manual in One Volume. By ALFRED EDWARD THAYER, M.D., Professor of Pathology, University of Texas. Second Edition, containing 131 illustrations. Philadelphia: P. Blakiston's Son & Co., 1012 Walnut Street. 1903. Canadian Agents: Chandler & Massey Limited, Toronto, Montreal and Winnipeg.

An abridgment such as this work is, containing reliable statements and facts, with the latest recognized theories and practical methods, will be invaluable to the student of pathology of to-day.

The author has amalgamated two compends of a former edition with this one of 692 pages, and has added a chapter on the nervous system and many fresh illustrations. The chapter on "Methods," containing a capital description of how a post-mortem examination, from beginning to end, should be conducted, will be found exceedingly useful.

The "get up" of the book is really unique as compared with medical works generally, being handsomely bound in the best loose leather style, and opens like a book should. We congratulate the publishers.

W. II. P.

A Practical Treatise on Smallpox. Illustrated by Colored Photographs from Life. By GEO. HENRY FOX, A.M., M.D., Consulting Dermatologist to the Health Department of New York City, with the collaboration of S. D. Hubbard, M.D., S. Pollitzer, M.D., and J. H. Huddleston, M.D. In two parts. Philadelphia and London: J. B. Lippincott Company. 1902. It does not fall to the lot of many to have the opportunity of studying smallpox in its different phases, and at its several stages, in life, so that the question of diagnosis depends largely upon the study of variola from plates. After studying those in Dr. Fox's two volumes, we do not hesitate to say that every general practitioner should expend the necessary amount to purchase the work, the plates being so excellent, so delicately tinted, and so true to life, that they are almost as valuable for diagnostic purposes as

the cases themselves could be. They are, in reality, works of art, and the firm of J. B. Lippincott & Co. are deserving of congratulation for their part of the work, and have proved that they turn out the very highest-class printing and lithography. The Canadian agent, from whom all the books of this firm can be obtained, is Chas. B. Roberts, Montreal.

A Manual of Medicine. Edited by W. H. ALLCHIN, M.D. (Lond.), F.R.C.P., F.R.S. (Edin.), Senior Physician and Lecturer on Clinical Medicine, Westminster Hospital; Examiner in Medicine in the University of London, and to the Medical Department of the Royal Navy. Volume II.-General Diseases Continued; Diseases Caused by Parasites, Diseases Determined by Poisons Introduced into the Body, Primary Perversions of General Nutrition, Diseases of the Blood. London: Macmillan & Co., Limited. New York: The Macmillan Company. 1900.

Through some mistake Volume II., a continuation on general disease, did not come to hand till this month, although Vols. I., III., IV., and, lately, V., were previously reviewed. We are always pleased to receive this work. The articles are short and to the point. They give you all you want on the subject, without tiresome reading. The work is thoroughly up-to-date, and we can with confidence recommend it to our friends. W. J. W.

Facetic Medicorum. The wit and humor of medicine in prose, poem and picture, gleaned from various sources and selected and reprinted from the files of "The Doctor's Factotum." Yonkers, N.Y.: The N. Y. Pharmacal Association.

This is worth sending for, and any physician enclosing his card to the publishers at Yonkers, N.Y., can receive a copy of " Facetiæ Medicorum." It will while away a pleasant hour on a winter's evening and cause many a healthy, hearty laugh.

Handsome Booklets on Antitoxin and Vaccine.--The firm of H. K. Mulford & Co., of Philadelphia, Pa., have recently issued exceedingly handsome booklets setting forth in full detail the manufacture of their different Serums from start to finish. The firm have certainly spared no expense in the work, and it will repay any physician to send for copies, which will be furnished him on application by remitting his professional card.

Listerine

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Listerine is a well-proven antiseptic agent-an antizymotic-especially useful in the management of catarrhal conditions of the mucous membrane, adapted to internal use, and to make and maintain surgically clean-aseptic -all parts of the human body, whether by spray, injection, irrigation, atomization, inhalation, or simple local application.

Listerine is a swift and sure destroyer of infusorial life; it prevents the various fermentations, preserves animal tissues and inhibits the activity, growth and motion of low forms of vegetable life: hence Listerine may be relied upon to destroy the activity of the living particles which constitute contagion whenever brought into intimate contact therewith.

For diseases of the uric acid diathesis: Lambert's Lithiated Hydrangea

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Be assured of genuine Listerine by purchasing an original package.

When writing advertisers, please mention THE CANADIAN JOURNAL OF MEDICINE AND SURGERY.

ALKALOIDAL THERAPY.*

BY C. L. EVANS, M.D.

It is an axiom that "a good thing can never grow old; " old enough, that is, I suppose, to cease to be good through age. This applies to my subject, "Alkaloidal Therapy," for, far from deteriorating with time and test, it, now no longer in swaddling clothes, becomes better and more alluring as one knows it more intimately.

"Alkaloidal Therapy" means to those who know it well, the quintessence of perfection in the exhibition of remedies; the most absolute certainty of the effect obtainable from such exhibition, and yields to those who use it with a positive knowledge of pathologic condition, the most remarkable curative results.

These may be, and indeed are, bold statements, which undoubtedly appear to the practician who still opposes to the certainties of disease the uncertainties of the old-time therapy, exaggerated or even absurd. But, gentlemen, each word I have used has been scrupulously weighed and is supported by actual experience, and my one object in presenting this paper is to induce you (or those of you who have not already done so) to apply that test yourselves, knowing that the adoption of the system by yourselves must follow.

In the very beginning "Alkaloidal Therapy" had for its parent dissatisfaction. A busy and thoughtful doctor fought, day by day, his hereditary enemy, with weapons which time and again proved "base metal." unreliable and ineffective, That which cut true to-day failed dismally to-morrow, and the most trusted weapon proved worthless in the most dire emergency. Then followed a period of casting away, of elimination. Gradually the doctor reduced his armamentarium to a few weapons (drugs) the composition and principles of which he thoroughly understood. And then, suddenly came light. Those weapons which proved true, were so, because he knew themknew just what they could and would do, and when they would do it. The others, those which had failed him, and the patients he would have protected so often, he had never understood.

They were complex; they were many-sided. Though they bore the same. name and appearance, they varied continuously in strength and usefulness. He gave opium which contains no less than 14 alkaloids; perchance the morphine salt was present in proper proportion and his patient, quieted and eased from pain, slept. He gave it again; morphine was lacking but the convulsive principles were there in full strength, and his patient trembled, tossed and tumbled into a delirium. He procured more and doubled the dose; in this specimen of the drug there was an excess of morphine and the patient died.

The doctor knew why he had been worsted in the battle with death sorely and so often; so being a wise man he hunted until he found and had properly labelled the active principle of the drugs he used. Some of these, present together, often in widely varying proportions, he found diametrically opposite to each in effect. Was it to be wondered at, that in administering them to get one result, another totally undesired developed?

What else could happen? What else does happen every day from the use of crude drugs, fluid extracts and tinctures? The answer is within your own hearts. But since that dissatisfied doctor isolated and studied the effects of

* Read before the Holt County Medical Society, Craig, Mo., April 7th, 1903.

Doctor I Need a Tonic.

The next time a patient says this to you, write a prescription for Colden's Liquid Beef Tonic. The patient may be right. He may be mentally and physically in a state of morbid depression. Everything may "go wrong" with him. A tissue-forming, stimulating restorative may be exactly the indication.

Order Colden's Liquid Beef Tonic in addition to your specific medication. There can be no mistake if you specify "Ext. carnis fl. Comp. (Colden)." Literature mailed to physicians on request.

THE CHARLES N. CRITTENTON CO.

115 117

Sole Agents for the United States,

FULTON STREET, NEW YORK.

Maltine

WITH

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Peristalsis Re-established and Permanently Maintained. Rendered Palatable by Combining the Bitter with the Sweet It is Especially Indicated in Constipation of Pregnancy. No Griping: No Nausea: nor any Distressing Re-action The System Nourished by Tonic Properties of Maltine. The Ideal Laxative for Children.

Upon application we will send to any physician who will pay express charges a case containing an eight ounce bottle of MALTINE with CASCARA SAGRADA and an eight ounce bottle of MALTINE, FERRATED, also a pamphlet on MALTINE and its Compounds with their formula.

THE MALTINE MANUFACTURING CO.

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