said, with the most serious and solemn aspect of countenance, that I was hysterical, which I knew was not so, for I was real sick, and he brought me around. a bottle of medicine, which had the most awful, horrid smell that I have ever experienced, and when I expressed my extreme disgust, he said with an utterly benign and unflinching face, 'that the medicine he was giving me had absolutely no odor at all,' and he smelt it time and time again, and kept on averring it; and by his intense look made me think that I might be mistaken, but still I could smell it, and when I took it to the druggist, he told me what it was, and said that its odor was sufficient, if I put it in the back yard, to attract every cat within twelve miles to that back yard. Now, he certainly lied to me, yet a more persistent and innocent looking liar, I never

saw.

Doctor Galen, again to his father: "Mrs. B. had hysterics last night, and she, like all hysterical women, imagines everything without there being any real element of truth of it, but I do candidly believe that it would take but little to convince that woman that I lied to her about the valerrianate of amonia not smelling.

Dr. Galen's diagnostic sense gradually became more and more pronounced. He could continually see defects where no one else could see them, and in his monomania, not infrequently proceeded with all due solemnity to diagnosticate normal human beings. His function

now seemed to grow largely in the realm of diagnosis and pathology; normal humanity were to him apparently few and far between, and so deeply became this pronounced monomania that he was constantly getting himself into trouble, from his misapplied, exalted and determined diagnostic application. He would constantly and unceasingly diagnosticate disease upon those who never complained nor sought his advice. The tales of his vagaries and mischievously applied suggestions spread rapidly amongst the people, so that his business began to suffer seriously, and this was viewed by his father, not only with alarm, but with the deepest concern. Said his father, "I do not know where this is going to end. His intensity and determination seem to be continued and serious, and I am in dread that he will do some bodily harm to some one, or some one will be compelled to defend themselves from him.” "Well," said Galen to his father, "I have just come from Mc's.; I found him suffering plainly from acute delirium, for when I arrived in the house he informed me that I was not wanted, but that you, yourself, must come at once. He positively and forcibly refused my attenticn, but when I saw the dangerous condition he was in, I proceeded to fill my hyperdermic syringe, determined to quiet him at any and all hazards by giving him an injection of atrophia and morphia; but to my utter surprise, when I endeavored to give him the injection, I was

knocked down by McS., and as I was held by his two neighbors, I was forcibly told that I was crazy; then I told him that I must be permitted to modify my diagnosis; that I certainly thought that he had symptoms of immortality; that even I might be an instrument to fix it so that he would never die again, but eternally live in a world of infinity. This man is certainly seriously delirious, hence I insist upon your going to see him, for I feel it imperative upon myself to control my anger, delirium or no delirium; for I am sad to confess to you, that I have an unusually aching desire to immortalize him."

McS. to Galen's father: "Why, my dear doctor, your son is, I am sorry to say, crazy, for no sane man would have acted as he did. Why, no matter what I said, he still continued to gaze at me with a fixed gaze of a lunatic; I told him that I was not sick, but that I had sent for you to see my wife, and that I only wanted you; but he insisted with that fixed stare, that almost influenced me, that I was in a dangerous condition, and he proceeded, in spite of all of our protestations, to treat me. He filled his hypodermic syringe, and with a glare of an angered tiger, came silently and insidiously towards me. I had to act, and found no other way of preventing him from injuring me than by knocking him down, aud calling the assistance of my two neighbors who are here to help me. It was with the utmost difficulty that we got him outside,

and as he stood outside, he very gravely said, that I had the symptoms of immortality and must surely die, even if he had to bring eternal life to me."

Galen's father to Professor L., to whom he had written for advice: "There has been, as I can plainly see, a constant and rapid change in Galen. in Galen. I have been compelled to keep him in the house, and will not permit him to attend to any one. I can see the change gradually come; he has become markedly unfeeling; he now inflicts absolute punishment and torture upon living animals. He not only treats cruelly these animals, but even seems to try and torture inanimate things. I found him out in the orchard cutting and bending down a series of small trees, so that they would bend and not stand erect; for, he said, 'that they were rigidly and cruelly upright.' Everything frets him, the movement of the leaves, the wind, the bellowing of a cow, or the neigh of a horse; he seems to be constantly fighting imaginary ills. It was only yesterday that I saw him start up wildly, talk aloud and gesticulate towards heaven. He is now busily engaged and trying to define various pathological conditions in insects. Again, he seems to be determinedly destructive, becoming more pessimistic than ever; everything is coming to destruction; his always pale face seems to be more elongated and misanthropic than ever. His fantacies and peculiarities are markedly profound. He

Sanmetto in Kidney and Bladder Affections and Enlarged Prostate.

J. Paterson Lewis, M.D., member British Medical Association, Medical Association, Alma, Dalbeattie, Scotland, says: "I have used Sanmetto in a large

number of cases of kidney and bladder affections with invariably good results. In several cases of old men, with enlarged prostrate, unable to keep their bed for only an hour or so during the night, it has given an amount of relief I could not have believed, seeing the supposed fixed cause, enlarged prostate; reducing their getting out of bed to one, two or three times during the night."

Illinois Central Hospital for the

Insane.

I have repeatedly prescribed Antikamnia for various neuroses with

upon the railway track and was killed by being run over: I learned in a letter from Dr. S., surgeon of the road, that, according to the engineer's report, when he saw this man, my son, that he was walking down the track with his back towards the engine, but turned when he heard the blowing of the whistle of the engine. fore the engine struck him, he never seemed to quail, but defiantly shook his fist, and started for the engine as though he would demolish it. After being picked up, when cruelly crushed, his only words were: 'Killed, killed, my God, by corporation's juggernaut.'

Be

good effect. Recently prescribed it in a it in a case of croupous enteritis, patient adult, highly nervous, and during continuance of paroxysms, and preceeding it, is nervous and hypochondriacal, suffering intense pain. The case is one of long standing, and one where opium was objectionable, because of the tendency toward forming opium habit. However, opium has been used, but the effect of Antikamnia has been more magical, more persistent, and followed by no digestive disturbance, as has been the case when opium was used.

My directions have been to use Antikamnia whenever a paroxysm occurs. Have also found it invincible in protracted neuralgia.

FRANK P. NORBURY, M.D. Jacksonville, Ills., September 19, 1891.

heart, thus giving us the trinity of modern surgery. We have mentioned these names, not in any invidious sense, or in any reflection upon others who are equally as

well qualified, perhaps, throughout the length and breadth of the land, but facts are facts, and must be acknowledged.

It is indeed with profound regret that we note the death of another of the great medical teachers of the world. Prof. Semmola became well known to American medical men through his paper read before the 9th Intarnational Congress, at Washington, and the sensational scene at that time will not be forgotten by those who participated in it.

We cannot do better in our obituary notice than to give to our readers the following most excellent editorial from The Medical Bulletin, of Philadelphia, edited by Dr. John V. Shoemaker.

DEATH OF PROF. MARIANO SEM

MOLA.

We have received with sorrow news of the death of Professor Semmola, of Naples. We learn from the Lancet that this distinguished teacher succumbed to a second apoplectic seizure. The deceased was born at Naples on January 31,

1831.

When 20 years old he presented to the Accademia di Medicina di Napoli three papers on Bright's Disease and and Albuminuria, and brought out in a striking manner

the great influenca of the azotized and non-azotized regimen on the quantity of albumin eliminated by the kidney in the twenty-four hours by sufferers from morbus Brightii. Proceeding to Paris he plunged into steady work, experimental and clinical, under Rager, Troussseau and Bernard, and earned the plaudits of a distinguished auditory at the institute for a monograph on Pathological Glycogenesis. On his return to Italy he resumed with increased knowledge and unabated ardor, his studies in albuminuria, a subject with which from 1861 to 1893, his name has been identified with numerous papers read before scientific bodies and medical congresses, national and international. In 1883 he had so favorably impressed the Paris school by what he had contributed to the pathology and therapeutics of the subject that at its instance the French Government decorated him with the "Legion of Honor" and the Academie de Medicine elected him corresponding member.

Academic employment came to him early and in abundance. In 1865 we find him in the chair of