called to the case. I found it in an emaciated condition, unable to move a limb, the bowel movements were frequent and watery; the little one was on the point of collapse: strychnia was administered hypodermically to stimulate the heart, after which diluted brandy was given every half hour. The colon was irrigated with 24 oz. of a 50 per cent aqueous solution of Glyco-Thymoline; I had the child under my observation for two and one-half weeks and with proper food and fresh air, the child made a good recovery.

Case No. 5.-M. M., a boy baby seven months of age, teething and causing all

NEW PHARMACEUTICAL LABORA-
TORIES.

The attention of the readers of this journal is directed to the catalogue recently issued by the H. K. Mulford Company.

The catalogue is completely classified and contains a full and complete table of contents and Therapeutic Index. Every physician should have a copy of this new list, as he will find it a ready and valuable book of reference.

For the more general introduction of the metric system, metric dosage on Fluid Extracts is included. This no doubt will be followed out more largely in future lists.

sorts of trouble for its parents, who were well-to-do. Was summoned to the house early one morning, found the little one vomiting quantities of curdled milk, and movements having a decidedly fetid odor. I tried most everything in this case and received but small relief by the use of Glyco-Thymoline. Upon careful investigation I found that the teeth were causing the trouble; the gums were then lanced, and the child's diet restricted; that is, the breast feedings were given at three hour intervals and only lasting five minutes at a time. Glyco-Thymoline was kept up with perseverance. With this and good nursing our little one soon got well.

Much space has been allowed in the new catalogue to special products and valuable information is furnished as to therapeutic action, dosage, etc.

Of special value and importance to the Medical Profession are the departments devoted to antitoxins and vaccines, describing fully the method of preparing the various biological products, in the preparation of which the Mulford Company have taken a most active part. To enhance and beautify the appearance of the catalogue, and to bring more vividly before its patrons the unsurpassed facilities which the H. K. Mulford Company enjoy for the scientific preparation of these products,

half-tone reproductions appear to illustrate the subject. The reproductions of the firm's new laboratories at Glenolden are convincing proofs of the sole purpose and desire of the firm to keep step with scientific advancement. In these new laboratories, entirely separate and removed from each other, and from the general pharmaceutical laboratories, all the antitoxin, vaccine, and various biological work is carried on. The very complete and thorough equipment, and the fact that each department is under the direction of scientific men, with world-wide reputations, is another sure evidence of the firm being in fullest accord with the latest scientific advancement.

The pharmaceutical laboratories of the firm, in Philadelphia, have by no means been overlooked in the work of improvement. A handsome new eight story building, with two basements, has been erected, adjoining their old pharmaceutical laboratories, and all the buildings have been equipped with the latest electrical devices, thus reducing the cost of manufacture to a minimum. In short, their entire mechanical equipment has been completely reconstructed, and brought up to the highest state of efficiency attainable. Economy has not been observed where improvements could be made.

While the growth of this firm is very unusual, yet it is not remarkable, because it is only the natural result and reward of the energy and honest effort put forth. The firm has only one aim, viz. to bring before the Medical and Pharmaceutical Professions the direct results of the latest scientific research work in the lines of bacteriology, pharmacology, and physiological chemistry.

Of much importance to the medical profession are some of the newer products of the firm, which are fully described in the catalogue, of which Somnos and Protan are being most favorably received.

Somnos is a definite synthetic product formed by the synthesis of chloræthanal alcoholate with a polyatomic alcohol radical.

This product gives prompt sedative and quieting effect and produces natural

sleep without affecting the heart or general circulation.

Protan is formed by the synthesis of tannin with nucleo-proteid. The astringent effects are not imparted to the system until the intestinal tract is reached where the tannic acid is slowly evolved and its astringent properties exerted exclusively upon the entire intestinal tract from the duodenum to the colon. Protan is of especial advantage in the treatment of children's diseases peculiar to the summer

season.

The firm of H. K. Mulford Company is to be congratulated upon the successful development of its business and the rapid strides it is making in advancing scientific work.

AN ASEPTIC THERMOMETER CASE. There is no doubt, as shown by repeated tests, that the bacterial flora found in the oral cavity can be transmitted by clinical thermometers. The question of preventing infection through the use of these instruments has long engaged the attention of thoughtful physicians; furthermore, so much has been written about the germ theory of disease that the laity, too, are becoming more concerned about the absolute cleanliness of instruments which pass from mouth to mouth. We believe, therefore, that the medical profession will welcome a practical pocket device for sterilizing clinical thermometers.

Heretofore, extreme and continued care have been necessary to keep thermometers sterile. Ordinary washing in water and then wiping upon a towel or handkerchief, will not free them from bacteria; neither will a few drops of antiseptic solution on a pledget of cotton carried in the thermometer case. To properly sterilize the thermometer, it must be immersed in an antiseptic solution or bath, strong enough to kill the germs, and be allowed to stay there for a sufficient length of time. The custom, adopted by hospitals, of keeping thermometers in a disinfecting solution is effective, but is not adapted to the needs of the general practitioner. The only practical and convenient device for the practicing

physician is the "Norwich" Antiseptic Thermometer Case. It is a pocket sterilizer that works while the thermometer is idle. It carries the thermometer immersed in an antiseptic solution and at the same time always available for use; is of convenient size and shape for vest pocket; will not leak or become broken in use; renders your thermometer sterile and keeps it so. It is, in effect, a pocket sterilizer; easy, automatic, and positive in its action. You simply return the thermometer to the case after use and it does the rest. The "Reporter" has arranged to supply its readers with this valuable instrument. See advertisement in another column.

ACNE DUE TO GENERAL WASTE. A. H. Ohmann-Dumesnil, A. M., M. D., St. Louis, Mo. Mrs. B., a pale blonde of twenty-six, came to see me for a cachectic acne with which she had suffered for several years. Her nourishment appeared below par and she steadily and slowly decreased in weight, complaining of lassitude and a general feeling of being unable to get about as she should. She was given the regular treatment for acne which I am in the custom of using, but it did not seem to produce the desired effect. Deeming that an improvement in her nutrition and assimilation would exercise a beneficial effect upon her cutaneous trouble, I ordered the following:

Rx Cord. ol morrhuae comp. (Hagee)-OZ xvi.

Sig. Tablespoonful after each meal and at

night.

In one week she reported a net gain of four pounds and the eruption was in better condition, so much so that the effect of the cordial was patent. From inquiry I elicited the fact that the appetite had increased, assimilation was better and a general sense of comfort had replaced the bad feeling which had formerly prevailed. At the present date, three months after the inception of the treatment, my patient weighs twenty-six pounds more and is rid of her acne.

I have used Hagee's Cordial with uniform good results, and it is without doubt

one of the best reconstructives now offered to the profession.

FERROLEUM AS A LIFTING POWER. The U. S. Ferrol Co., of Buffalo, publish by consent an interesting Clinical Report of their preparation "Ferroleum," made by the late Dr. Maurice Bucke, of London, Canada, at that time Medical Superintendent of the Asylum for the Insane. Dr. Bucke was well and favorably known to the medical profession throughout the United States and Canada and was acknowledged to be one of the foremost alienists of the day, besides being an author of considerable repute.

The test made by Dr. Bucke was a severe one and was made for the purpose of demonstrating the "lifting" power of the preparation. Ten patients were selected, all chronics, with weight and physique generally, stationary. No change was made in their diet or treatment in any way except to add "Ferroleum" to whatever was being done for them. The result is given in Dr. Bucke's own words, "In this experiment 25 bottles were given to ten patients and the aggregate weight of the patients was increased 951⁄2 lbs.

If these patients had been convalescing from an acute disease we should not be surprised at the effect produced; but considering all the circumstances I think that without any exaggeration it may be called extraordinary."

A FAMOUS EXPRESSION.

Prof. Gibson, one of the pioneers in the development of scientfic medical teaching in the United States, was asked, by one of his students at the University of Pennsylvania, how to obtain a comprehensive, accurate knowledge of medicine that would enable the physician to make a correct diagnosis, and execute proper treatment. Dr. Gibson's reply has become inseparably connected with his name and memory. It was "Principles, principles, principles." By this, of course, was meant that however varied were the manifestations of disease, they were to be comprehensively grasped only by a knowledge of the fun

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damental principles of physiology, pathology and therapeutics. The symptoms of disease, however manifold, could be intelligently interpreted only on this philosophic basis. Strictly consistent with this inexorable law is the fact that all conditions of depression and exhaustion of the system can be appropriately and effectively treated only by re-awakening the dormant and torpid nutritive functions. The crying need of the emaciated tissues and impaired vital functions is for food, the natural restorative. In most cases, however, there is not only an indisposition to take food, but the digestive organs are so enfeebled that they cannot digest and assimilate food-their functions are suspended.

The first indispensable step is to restore these functions. The ordinary tonics-iron, arsenic, strychnine, hypophosphites, etc.-fail entirely to accomplish this object.

No Collection, No Charge.

Cod liver oil is the heaviest burden on even the strongest digestive powers to prepare for assimilation; on the atonic stomach it is an irritant-it aggravates the existing trouble. The digestive organs must be gradually coaxed into a condition of restored functions; they need stomachic alteratives, tonics and stimulants.

The best of these, as proven by experience, is Gray's Glycerine Tonic Comp. It has a specific, selective action upon the atonic digestive organs; it not only enables them to digest food, but it invariably promotes assimilation, so that reconstruction of wasted tissues and nervous force is absolutely assured. For this reason Gray's Glycerine Tonic Comp. is the most rational, scientific and effective remedy in all conditions of malnutrition, anæmia and nervous exhaustion, occurring either independently as a consequence of organic disease, such as tuberculosis, Bright's disease, or as the result of acute infectious diseases.

Vol. X.

No. 9

SYSTEMATIC WORK IN COLLEGES. How many physicians who have students in attendance at college, investigate for themselves the way in which instruction is imparted to them? We raise the point because we are convinced that a large number of preceptors get their information as to the details of college work from the students themselves and not from a careful study of the curriculum of the college and the methods of instruction. do not underestimate the opinion of students, but at best their judgment, at least until it is retrospective, cannot be a safe one to follow.

We

We believe that the most vital part of college work is the curriculum. We assume, of course, that the teaching corps is competent, that the clinical and laboratory facilities are adequate and that the work as scheduled is honestly carried out. These are the points upon which the student's testimony is competent. The details of the curriculum, however, require the mature consideration of one who has graduated in medicine and knows what ought to be and ought not to be.

It is manifestly impossible to incorporate in a four years' course, all or even a large part of present medical knowledge.

The

task of choosing essential subjects, the arrangement of their sequence and the time allotted to each are of vital importance in making up the curriculum. It is to these facts that the preceptor should direct his attention in considering the work of a college. An examination of the curricula of some of our colleges will show that little attention has been given to the systematic arrangement of the work. It is true that in the first and second years some preliminary work is done, but the arrangement is not systematic and hours are filled with advanced studies. Over half of our homeopathic colleges double up a large part of their classes. Their schedules show that the two classes are together taking the same work. It is to be hoped that in all of them there is an arrangement of subjects so that the student does not receive the same lectures or text-book work twice, for such methods are not consistent with the theories of a graded course.

The institution of a graded course in medical colleges was one of the distinct steps forward in medical education. Its results to the student are incalculable and in no other way could it have been possible to cover in an adequate way the range of present medical knowledge.